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- All HBS Web
(1,833)
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- News (171)
- Research (1,465)
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- Faculty Publications (1,157)
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- March 2010 (Revised May 2012)
- Case
Myelin Repair Foundation: Accelerating Drug Discovery Through Collaboration
By: Karim R. Lakhani and Paul R. Carlile
This case presents the Myelin Repair Foundation's accelerated research collaboration model for drug discovery. It highlights the challenges of building a multi-disciplinary and multi-institutional research collaboration that is attempting to create a treatment for... View Details
Keywords: Research and Development; Intellectual Property; Risk and Uncertainty; Strategic Planning; Collaborative Innovation and Invention; Health Disorders; Pharmaceutical Industry; Biotechnology Industry; Health Industry
Lakhani, Karim R., and Paul R. Carlile. "Myelin Repair Foundation: Accelerating Drug Discovery Through Collaboration." Harvard Business School Case 610-074, March 2010. (Revised May 2012.)
- April 2002
- Teaching Note
Managing Technology Ventures - Module Teaching Note (TN)
Describes the conceptual foundations for a module on venture design, which forms part of an MBA course called Managing Technology Ventures. The objective of the course is to teach students how to think critically about the design of a technology venture, using cases... View Details
- January 2018 (Revised April 2021)
- Case
Capital Allocation at HCA
By: W. Carl Kester and Emily R. McComb
In early 2017, HCA Holdings, an investor-owned hospital management company, faced a strategically important capital allocation decision. After the exit of its private equity sponsors in 2016, HCA had to determine how best to allocate its substantial annual free cash... View Details
Keywords: Capital Allocation; Cash Distribution Policy; Dividends; Share Repurchases; Growth Strategy And Execution; Growth Investing; Capital Expenditures; Debt Management; Debt Reduction; Debt Policy; Hospital Management; Investor-owned Hospital Chains; Capital Budgeting; Capital Structure; Cash Flow; Corporate Finance; Decision Choices and Conditions; Health Industry; United States
Kester, W. Carl, and Emily R. McComb. "Capital Allocation at HCA." Harvard Business School Case 218-039, January 2018. (Revised April 2021.)
- October 2002 (Revised December 2003)
- Case
Collabrys, Inc. (A)-The Evolution of a Startup
By: Dorothy A. Leonard and Brian DeLacey
The CEO of a two-year-old start-up must now decide whether to become a technology provider or a service agency. In a time of enormous uncertainty about the viability of various business models for Internet-delivered services and products, Collabrys has survived the... View Details
Keywords: Risk and Uncertainty; Internet and the Web; Corporate Entrepreneurship; Corporate Strategy; Technological Innovation; Cost vs Benefits; Partners and Partnerships; Business Growth and Maturation; Business Startups; Corporate Finance; United States
Leonard, Dorothy A., and Brian DeLacey. "Collabrys, Inc. (A)-The Evolution of a Startup." Harvard Business School Case 603-064, October 2002. (Revised December 2003.)
- July 2003
- Article
Probabilistic Representation of Complexity
By: Nabil I Al-Najjar, Ramon Casadesus-Masanell and Emre Ozdenoren
We study individuals' behavior in an environment that is deterministic, but too complex to permit tractable deterministic representation. Under mild conditions, behavior is represented by a unique probabilistic model in which the agent's inability to think through all... View Details
Al-Najjar, Nabil I., Ramon Casadesus-Masanell, and Emre Ozdenoren. "Probabilistic Representation of Complexity." Journal of Economic Theory 111, no. 1 (July 2003): 49–87.
- July 2021 (Revised December 2021)
- Case
Pershing Square's Pandemic Trade (A)
By: Emil N. Siriwardane, Luis M. Viceira, Dean Xu and Lucas Baker
This case explores the decision that Bill Ackman, CEO and founder of the hedge fund Pershing Square Capital, was considering in late February 2020 about hedging the exposure of the fund’s portfolio from the potential financial fallout ensuing from an extreme event like... View Details
Keywords: Health Pandemics; Financial Liquidity; Cost Management; Decision Choices and Conditions; Risk Management
Siriwardane, Emil N., Luis M. Viceira, Dean Xu, and Lucas Baker. "Pershing Square's Pandemic Trade (A)." Harvard Business School Case 222-007, July 2021. (Revised December 2021.)
- 2023
- Working Paper
Complexity and Time
By: Benjamin Enke, Thomas Graeber and Ryan Oprea
We provide experimental evidence that core intertemporal choice anomalies -- including extreme short-run impatience, structural estimates of present bias, hyperbolicity and transitivity violations -- are driven by complexity rather than time or risk preferences. First,... View Details
Enke, Benjamin, Thomas Graeber, and Ryan Oprea. "Complexity and Time." NBER Working Paper Series, No. 31047, March 2023.
- January 2021 (Revised March 2021)
- Supplement
Juno (B): Leveraging Student Power
By: Joshua Schwartzstein, Kathleen L. McGinn and Amy Klopfenstein
In March 2020, Juno co-founders Chris Abkarians and Nikhil Agarwal decided to pitch banks in anticipation of their annual auction while negotiating directly with private lender Eager. Responses from the majority of private lenders—including Juno’s 2019 partner—were not... View Details
Keywords: Decision Making; Decision Choices and Conditions; Decisions; Cost vs Benefits; Judgments; Education; Higher Education; Finance; Borrowing and Debt; Strategy; Adaptation; Alignment; Negotiation; Negotiation Deal; Negotiation Offer; Negotiation Participants; Negotiation Process; Negotiation Types; Financial Services Industry; Education Industry; North and Central America; United States; Massachusetts; Boston
Schwartzstein, Joshua, Kathleen L. McGinn, and Amy Klopfenstein. "Juno (B): Leveraging Student Power." Harvard Business School Supplement 921-033, January 2021. (Revised March 2021.)
- Article
'Making Book Against Oneself,' the Independence Axiom, and Non-Linear Utility Theory
By: Jerry R. Green
An individual with known preferences over lotteries can be led to accept random wealth distributions different from his initial endowment by a sequential process in which some uncertainty is resolved and he is offered a new lottery in place of the remaining... View Details
Green, Jerry R. "'Making Book Against Oneself,' the Independence Axiom, and Non-Linear Utility Theory." Quarterly Journal of Economics 102, no. 4 (November 1987): 785–796.
- March 2006
- Module Note
Managing Innovation in an Uncertain World: Module 4: Sensing Opportunity
Describes the fourth module of the 30-session Harvard Business School elective course Managing Innovation in an Uncertain World. The course helps students understand the challenges that uncertainty implies for innovation and how to overcome them. The course emphasizes... View Details
Keywords: Innovation and Management; Problems and Challenges; Management Analysis, Tools, and Techniques; Projects; Opportunities; Risk and Uncertainty; Perspective; Value Creation; Networks; Alignment
MacCormack, Alan D. "Managing Innovation in an Uncertain World: Module 4: Sensing Opportunity." Harvard Business School Module Note 606-104, March 2006.
- March – April 2009
- Article
Market Research and Innovation Strategy in a Duopoly
By: Dominique Lauga and Elie Ofek
We model a duopoly in which ex-ante identical firms must decide where to direct their innovation efforts. The firms face market uncertainty about consumers' preferences for innovation on two product attributes and technology uncertainty about the success of their R&D... View Details
Keywords: Profit; Innovation and Management; Demand and Consumers; Duopoly and Oligopoly; Research and Development; Competitive Strategy
Lauga, Dominique, and Elie Ofek. "Market Research and Innovation Strategy in a Duopoly." Marketing Science 28, no. 2 (March–April 2009): 373–396.
- October 2024 (Revised May 2025)
- Case
Southern California Industrial: Freezer Drive
By: Arthur I Segel, Dwight Angelini and W. Matt Kelly
In the midst of the COVID-19 pandemic, a Boston based real estate private equity firm was seeking to make their very first West Coast investments in hopes of establishing their presence in the strategic region. An exciting property suddenly became available on the... View Details
Keywords: Real Estate Development; Acquisition; Health Pandemics; Risk and Uncertainty; Expansion; Cost vs Benefits; Investment Return; Real Estate Industry
Segel, Arthur I., Dwight Angelini, and W. Matt Kelly. "Southern California Industrial: Freezer Drive." Harvard Business School Case 225-015, October 2024. (Revised May 2025.)
- January 2014 (Revised June 2015)
- Case
Amgen Inc.: Pursuing Innovation and Imitation? (A)
By: Ian W. Mackenzie
Set in 2009, the (A) case explores whether Amgen, a leading innovator of biotech-based drugs, should enter the emerging business of biosimilars (BS), which are essentially 'me-too' products. There appear to be sound reasons to explore this related diversification:... View Details
Mackenzie, Ian W. "Amgen Inc.: Pursuing Innovation and Imitation? (A)." Harvard Business School Case 714-424, January 2014. (Revised June 2015.)
- 1977
- Working Paper
Mitigating Demographic Risk Through Social Insurance
By: Jerry R. Green
A two-period lifetime overlapping generations growth model is used to evaluate the possibility that social insurance can effectively offset economic risks associated with uncertainty about the rate of population growth. Crude measures of the seriousness of this type of... View Details
Keywords: Social Insurance; Econometric Models; Public Sector; Government Administration; Policy; Human Needs; Social Issues; Risk and Uncertainty
Green, Jerry R. "Mitigating Demographic Risk Through Social Insurance." NBER Working Paper Series, No. 215, November 1977.
- December 2021
- Article
Auctioneers Sometimes Prefer Entry Fees to Extra Bidders
By: Jiafeng Chen and Scott Duke Kominers
We investigate a market thickness–market power tradeoff in an auction setting with endogenous entry. We find that charging admission fees can sometimes dominate the benefit of recruiting additional bidders, even though the fees themselves implicitly reduce competition... View Details
Chen, Jiafeng, and Scott Duke Kominers. "Auctioneers Sometimes Prefer Entry Fees to Extra Bidders." Art. 102737. International Journal of Industrial Organization 79 (December 2021).
- January 2017 (Revised December 2020)
- Case
Turkey and Russia: Dangerous Liaisons
By: Rawi Abdelal, Esel Çekin, Eren Kuzucu and Gamze Yucaoglu
The case opens in November 2015, after the Turkish military’s shooting down of a Russian military airplane over the Turkish-Syrian border. The incident threatened to undermine the countries’ political and economic ties, and starting from late 2015, the dialogue between... View Details
Keywords: Business ＆ Government Relations; Politics; Natural Gas; Natural Resources; Nuclear Power; Business and Government Relations; Energy Policy; Infrastructure; Energy; Strategy; International Relations; Russia; Turkey
Abdelal, Rawi, Esel Çekin, Eren Kuzucu, and Gamze Yucaoglu. "Turkey and Russia: Dangerous Liaisons." Harvard Business School Case 717-035, January 2017. (Revised December 2020.)
- September 2016
- Case
Generali: Paving the Way for CEE Expansion
By: Dante Roscini and Emer Maloney
Generali was one of Italy’s largest companies and one of Europe’s largest insurers and had for decades been at the center of the web of cross-shareholding that has characterized the opaque brand of old Italian capitalism. This bred sub-par returns while serving to... View Details
Keywords: Joint Ventures; Transformation; Insurance; Emerging Markets; Negotiation Deal; Business and Shareholder Relations; Expansion; Business Strategy; Insurance Industry; Italy; Europe
Roscini, Dante, and Emer Maloney. "Generali: Paving the Way for CEE Expansion." Harvard Business School Case 717-016, September 2016.
- June 1999 (Revised March 2004)
- Case
Sirona
By: Walter Kuemmerle and Chad S Ellis
Sirona, the dental systems business of Siemans AG is being sold through an auction. In September 1997, buyout firm Schroder Ventures has to decide whether to make a binding offer for the business. Schroder has done extensive due diligence with support from a team of... View Details
- November 2003 (Revised August 2005)
- Case
Reinventing the Automobile: General Motors' AUTOnomy Project
By: Alan D. MacCormack and Kerry Herman
Describes the history of General Motor's attempts to develop a hydrogen fuel-cell powered car. As of 2003, GM developed several prototypes of such a vehicle to demonstrate the viability of the overall concept. Many uncertainties remained, however, with respect to the... View Details
Keywords: Problems and Challenges; Management; Information Technology; Transition; Competency and Skills; Disruptive Innovation; Machinery and Machining; Auto Industry
MacCormack, Alan D., and Kerry Herman. "Reinventing the Automobile: General Motors' AUTOnomy Project." Harvard Business School Case 604-064, November 2003. (Revised August 2005.)
- 17 Apr 2012
- Working Paper Summaries