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  • November 2009 (Revised March 2010)
  • Case

Managing Drugs on the Forefront of Personalized Medicine: The Erbitux and Vectibix Story

By: Richard G. Hamermesh, Raju Kucherlapati and Rachel Gordon
In May 2007, Amgen Inc. (Amgen) received disappointing news from the European Medicines Agency (EMEA) that its drug Vectibix, developed to fight metastatic colorectal cancer, had been rejected. This was especially surprising news given that a similar rival drug had... View Details
Keywords: Entrepreneurship; Governing Rules, Regulations, and Reforms; Health Testing and Trials; Marketing Strategy; Product Positioning; Genetics; Biotechnology Industry; Europe; United States
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  • 04 Sep 2019
  • News

Advancing Diagnostics that Can Save Lives

facilities detect and control outbreaks of health care–associated infections. Lee notes that services like epiXact are not DZD’s primary objective, but they are critical to “developing customer instincts and building commercial muscle”... View Details
Keywords: Susan Young
  • Web

Teaching Cases - Institute For Strategy And Competitiveness

joint venture with a community hospital to establish Hoag Orthopedic Institute, a for-profit hospital and two ambulatory service centers. By controlling and integrating all aspects of the patients' medical treatment, the physicians... View Details
  • 10 Nov 2015
  • First Look

November 10, 2015

communication and collaboration between practitioners and academics by introducing key vocabulary and concepts used in rigorous impact evaluation methods, starting with randomized controlled View Details
Keywords: Sean Silverthorne
  • 01 May 2007
  • First Look

First Look: May 1, 2007

that firms focusing on a particular task—at either a divisional or firm level—experience higher output and productivity with respect to that task than unfocused firms. After controlling for selection, scale, and learning effects, we find... View Details
Keywords: Sean Silverthorne
  • 24 Jul 2019
  • Lessons from the Classroom

Can These Business Students Motivate Londoners to Do the Right Thing?

unintended consequences..." The approach has really taken hold in policy settings, and there are now many teams in governments focused on bringing behavioral insights and randomized controlled View Details
Keywords: by Dina Gerdeman
  • 13 Aug 2018
  • Blog Post

Following My Dream: Launching a Venture

smoothie increases happiness and is also a great socializing experience: more than 40% of our users stated to have met someone new or interacted with a colleague they had not talked to for a long time. The highlight so far was certainly a weeklong View Details
Keywords: Entrepreneurship
  • 2010
  • Chapter

From Visible Harm to Relative Risk: Centralization and Fragmentation of Pharmacovigilance

By: Arthur A. Daemmrich
Adverse drug reactions pose distinct but potentially catastrophic risks to patients, physicians, pharmaceutical firms, and regulators. Between the early 1960s and the present, national systems were built to collect, standardize, and respond to individual reports of... View Details
Keywords: Governing Rules, Regulations, and Reforms; Health Testing and Trials; Business and Government Relations; Risk and Uncertainty; Safety; Pharmaceutical Industry; United States
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  • 01 Jun 2012
  • News

Pitfalls, Trade-Offs, Dreaming Big

entrepreneurs such as Tim Westergren of Pandora and Evan Williams of Twitter. YouTube cofounder and former CEO Chad Hurley has called the book “an invaluable alternative to real-world trial and error.” A past recipient of the HBS... View Details
Keywords: Garry Emmons; Health, Social Assistance; Data Processing, Hosting, and Related Services; Information; News, Library, Internet, and Other Services; Information
  • 01 Mar 2016
  • News

Off Script

control. They also control health funding deficits by encouraging, or even requiring, their main populations to aggressively set aside medical savings during their earning years to help with older age health care. Such actions are much... View Details
Keywords: Insurance Carriers and Related Activities; Finance
  • 2013
  • Working Paper

What Makes the Bonding Stick? A Natural Experiment Involving the U.S. Supreme Court and Cross-Listed Firms

By: Amir N. Licht, Christopher Poliquin, Jordan I. Siegel and Xi Li
On March 29, 2010, the U.S. Supreme Court signaled its intention to geographically limit the reach of the U.S. securities antifraud regime and thus differentially exclude U.S.-listed foreign firms from the ambit of formal U.S. antifraud enforcement. We use this legal... View Details
Keywords: Crime and Corruption; International Finance; Investment; Corporate Governance; Governing Rules, Regulations, and Reforms; Courts and Trials; Legal Liability; United States
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  • 17 Jul 2012
  • First Look

First Look: July 17

institutional appropriateness was the stronger requirement; the lack of it prevented an otherwise informationally relevant risk control system from prevailing as an interactive control system. Download the... View Details
Keywords: Sean Silverthorne
  • 17 Mar 2009
  • First Look

First Look: March 17, 2009

Microfinance in particular has often been argued, but not without controversy, to be a tool for empowering women. Here, using a randomized controlled trial, we examine whether access to, and marketing of, an... View Details
Keywords: Martha Lagace
  • 18 Oct 2024
  • News

My Worst Job

ended up, buying a piece of and running a dredging marine construction company for about 12 years, which I sold in 2018. It ended up coming a little more full circle. It certainly was not part of the grand career plan. But I've had a little bit of a View Details
  • 13 Feb 2013
  • Research & Ideas

5 Weight Loss Tips From Behavioral Economists

The researchers found that the financial incentive group lost significantly more weight in 32 weeks than did the control group. (Unfortunately, much of the weight came back after the eight-month trial was... View Details
Keywords: by Carmen Nobel
  • 10 Oct 2000
  • Research & Ideas

Cross-Sector Collaboration: Lessons from the International Trachoma Initiative

scientific field of trachoma control forward and now had the opportunity to "finish the job." That is, it could help to make operational its research in a way that directly improved the lives of disadvantaged people, the core... View Details
Keywords: by Diana Barrett, James Austin & Sheila McCarthy
  • 01 Dec 2020
  • News

New Releases: Alumni and Faculty Books

help you take active steps toward achieving your dream life. Former Wall Street investor, adviser, and author Tiffany Kent infuses specific investment advice with her personal story to show you how to take control of your finances and... View Details
Keywords: Margie Kelley
  • Web

Israel - Global Activities 2021

incompletely understood notion,” explains Reinhardt. Netafim was founded in Israel’s Negev desert in 1965. Since then, the firm, whose tagline is “grow more with less,” has learned through trial and error how to combine precision... View Details
  • 10 May 2016
  • First Look

May 10, 2016

Publisher's link: https://www.hbs.edu/faculty/Pages/item.aspx?num=51040 forthcoming American Journal of Health Promotion The Effect of Cost Sharing on an Employee Weight Loss Program: A Randomized Trial By:... View Details
Keywords: Carmen Nobel
  • 22 Apr 2014
  • First Look

First Look: April 22

Nava, Diego Aycinena, Claudia Martínez A., and Dean Yang Abstract—While remittance flows to developing countries are very large, it is unknown whether migrants desire more control over how remittances are used. This research uses a View Details
Keywords: Sean Silverthorne