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Show Results For
- All HBS Web
(942)
- People (3)
- News (246)
- Research (503)
- Events (4)
- Multimedia (6)
- Faculty Publications (262)
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- Research Summary
Clinical Trials as a setting for Health Policy and Management Research
The clinical trial marketplace is in flux. A decade ago, pharmaceutical firms almost exclusively conducted the study of their novel drug compounds within major academic medical centers. But today, industry-sponsored clinical trials are increasingly using community... View Details
- December 1999 (Revised August 2001)
- Case
Millennium Pharmaceuticals, Inc. (A)
By: Stefan H. Thomke and Ashok Nimgade
Focuses on Millennium's strategy to grow and revolutionize drug development through the use of new technologies such as genomics. Describes how Millennium Pharmaceuticals--a fast-growing biotechnology firm in Cambridge, MA--has used strategic alliances to finance the... View Details
Keywords: Cost Management; Financing and Loans; Medical Specialties; Retention; Growth and Development Strategy; Time Management; Product Development; Problems and Challenges; Alliances; Technology; Biotechnology Industry; Pharmaceutical Industry; Cambridge
Thomke, Stefan H., and Ashok Nimgade. "Millennium Pharmaceuticals, Inc. (A)." Harvard Business School Case 600-038, December 1999. (Revised August 2001.)
- 09 Mar 2009
- Research & Ideas
How to Revive Health-Care Innovation
fundamental question: How do we make health care affordable? Most disruptions have three enablers: a simplifying technology, a business model innovation, and a disruptive value network. The technological enabler transforms a View Details
- 19 Jun 2018
- First Look
New Research and Ideas, June 19, 2018
much more limited application. Early diffusion was accordingly rapid in these narrower applications but limited in scope until tractor technology generalized. The sequence of diffusion is consistent with a model of research and... View Details
Keywords: Dina Gerdeman
- 2019
- Working Paper
Soul and Machine (Learning)
By: Davide Proserpio, John R. Hauser, Xiao Liu, Tomomichi Amano, Alex Burnap, Tong Guo, Dokyun Lee, Randall Lewis, Kanishka Misra, Eric Schwarz, Artem Timoshenko, Lilei Xu and Hema Yoganarasimhan
Machine learning is bringing us self-driving cars, improved medical diagnostics, and machine translation, but can it improve marketing decisions? It can. Machine learning models predict extremely well, are scalable to “big data,” and are a natural fit to rich media... View Details
Proserpio, Davide, John R. Hauser, Xiao Liu, Tomomichi Amano, Alex Burnap, Tong Guo, Dokyun Lee, Randall Lewis, Kanishka Misra, Eric Schwarz, Artem Timoshenko, Lilei Xu, and Hema Yoganarasimhan. "Soul and Machine (Learning)." Harvard Business School Working Paper, No. 20-036, September 2019.
- May 2021
- Article
Value-Based Healthcare in Urology: A Collaborative Review
By: Chanan Reitblat, Paul A. Bain, Michael E. Porter, David N. Bernstein, Thomas W. Feeley, Markus Graefen, Santosh Iyer, Matthew J. Resnick, C.J. Stimson, Quoc-Dien Trinh and Boris Gershman
Context:
In response to growing concerns over rising costs and major variation in quality, improving value for patients has been proposed as a fundamentally new strategy for how healthcare should be delivered, measured, and... View Details
In response to growing concerns over rising costs and major variation in quality, improving value for patients has been proposed as a fundamentally new strategy for how healthcare should be delivered, measured, and... View Details
Keywords: Value-based Healthcare; Integrated Practice Units; Outcome Measurement; Time-Driven Activity-Based Costing; Health Care and Treatment; Value; Cost Management; Strategy; Outcome or Result; Measurement and Metrics
Reitblat, Chanan, Paul A. Bain, Michael E. Porter, David N. Bernstein, Thomas W. Feeley, Markus Graefen, Santosh Iyer, Matthew J. Resnick, C.J. Stimson, Quoc-Dien Trinh, and Boris Gershman. "Value-Based Healthcare in Urology: A Collaborative Review." European Urology 79, no. 5 (May 2021): 571–585.
- 26 Apr 2023
- Cold Call Podcast
How Martine Rothblatt Started a Company to Save Her Daughter
- 27 Feb 2007
- First Look
First Look: February 27, 2007
instead reflect more "top-down" interventions. We conclude with a discussion of some of the historical evidence on top-down interventions. Illicit Invention: Tracing Technological Development in the Shadow of the Law... View Details
Keywords: Martha Lagace
- Article
National Trends in the Safety Performance of Electronic Health Record Systems From 2009 to 2018
By: David Classen, A Jay Holmgren, Zoe Co, Lisa Newmark, Diane Seger, Melissa Danforth and David Bates
Importance Despite the broad adoption of electronic health record (EHR) systems across the continuum of care, safety problems persist.
Objective To measure the safety performance of operational EHRs in hospitals across the country during a 10-year period.
Design,... View Details
Keywords: Electronic Health Record Systems; Health Care and Treatment; Information Technology; Performance; Safety; Measurement and Metrics; United States
Classen, David, A Jay Holmgren, Zoe Co, Lisa Newmark, Diane Seger, Melissa Danforth, and David Bates. "National Trends in the Safety Performance of Electronic Health Record Systems From 2009 to 2018." JAMA Network Open 3, no. 5 (May 2020).
- 23 Jan 2008
- First Look
First Look: January 23, 2008
Authors:Michel Anteby and Mikell Hyman Periodical:Social Science & Medicine (forthcoming) Abstract Human cadavers are crucial to medical science. While the debate on how to secure sufficient cadavers has focused primarily on donors'... View Details
Keywords: Martha Lagace
- Article
Advancing Digital Health Applications: Priorities for Innovation in Real-World Evidence Generation
By: Ariel Dora Stern, Jan Brönneke, Jörg F Debatin, Julia Hagen, Henrik Matthies, Smit Patel, Ieuan Clay, Bjoern Eskofier, Annika Herr, Kurt Hoeller, Ashley Jaksa, Daniel B Kramer, Mattias Kyhlstedt, Katherine T Lofgren, Nirosha Mahendraratnam, Holger Muehlan, Simon Reif, Lars Riedemann and Jennifer C Goldsack
In 2019, Germany passed the Digital Healthcare Act, which, among other things, created a “Fast-Track” regulatory and reimbursement pathway for digital health applications in the German market. The pathway explicitly provides for flexibility in how researchers can... View Details
Stern, Ariel Dora, Jan Brönneke, Jörg F Debatin, Julia Hagen, Henrik Matthies, Smit Patel, Ieuan Clay, Bjoern Eskofier, Annika Herr, Kurt Hoeller, Ashley Jaksa, Daniel B Kramer, Mattias Kyhlstedt, Katherine T Lofgren, Nirosha Mahendraratnam, Holger Muehlan, Simon Reif, Lars Riedemann, and Jennifer C Goldsack. "Advancing Digital Health Applications: Priorities for Innovation in Real-World Evidence Generation." Lancet Digital Health 4, no. 3 (March 2022): e200–e206.
- September 2014
- Case
FormPrint Ortho500
By: Frank V. Cespedes and Alisa Zalosh
The Senior Vice President of FormPrint's Medical Products business unit is considering issues raised by the upcoming introduction of a new 3D printing system, the Ortho500, which could print custom exoskeletal orthopedic splints, braces, and casts that conformed to a... View Details
Keywords: B2B Marketing; Technological Innovation; Market Entry and Exit; Marketing Strategy; Distribution Channels; Product Development; Medical Devices and Supplies Industry
Cespedes, Frank V., and Alisa Zalosh. "FormPrint Ortho500." Harvard Business School Brief Case 915-535, September 2014.
- July–August 2021
- Article
Lowering the Bar? External Conditions, Opportunity Costs, and High-Tech Startup Outcomes
By: Annamaria Conti and Maria P. Roche
We assess the heterogeneous impact of economic downturns on individuals’ decisions to bring high-technology ideas to the market in the form of new ventures. We thereby examine how worsening labor market conditions influence individuals’ opportunity costs of starting... View Details
Keywords: Necessity Entrepreneurship; Economic Conditions; Recessions; High-tech Startups; Opportunity Costs; Entrepreneurship; Economic Slowdown and Stagnation; Business Startups; Information Technology; Performance; Labor
Conti, Annamaria, and Maria P. Roche. "Lowering the Bar? External Conditions, Opportunity Costs, and High-Tech Startup Outcomes." Organization Science 32, no. 4 (July–August 2021): 965–986.
- Article
Soul and Machine (Learning)
By: Davide Proserpio, John R. Hauser, Xiao Liu, Tomomichi Amano, Burnap Alex, Tong Guo, Dokyun (DK) Lee, Randall Lewis, Kanishka Misra, Eric Schwarz, Artem Timoshenko, Lilei Xu and Hema Yoganarasimhan
Machine learning is bringing us self-driving cars, medical diagnoses, and language translation, but how can machine learning help marketers improve marketing decisions? Machine learning models predict extremely well, are scalable to “big data,” and are a natural fit to... View Details
Keywords: Machine Learning; Marketing Applications; Knowledge; Technological Innovation; Core Relationships; Marketing; Applications and Software
Proserpio, Davide, John R. Hauser, Xiao Liu, Tomomichi Amano, Burnap Alex, Tong Guo, Dokyun (DK) Lee, Randall Lewis, Kanishka Misra, Eric Schwarz, Artem Timoshenko, Lilei Xu, and Hema Yoganarasimhan. "Soul and Machine (Learning)." Marketing Letters 31, no. 4 (December 2020): 393–404.
- July 2002 (Revised August 2002)
- Case
Washington Hospital Center (C): Progress and Prospects, 1995-2001
By: Rosabeth M. Kanter and Michelle Heskett
Dr. Craig Feied and Dr. Mark Smith have already transformed a "worst-in-area" emergency medicine department into the best in the area. Industry-wide and hospital system-specific challenges remain, including their newest project of national importance--creating an... View Details
- 14 Dec 2021
- Op-Ed
To Change Your Company's Culture, Don't Start by Trying to Change the Culture
something you fix Consider Vince Forlenza’s experience, as former CEO of medical technology maker Becton Dickinson, in developing a more innovative culture to meet the changing competitive landscape. He... View Details
Keywords: by Michael Beer
- 23 Jun 2009
- First Look
First Look: June 23
to choose a home page provided by a competitor). The second principle focuses on opportunity: specifically, opportunity that is facilitated by giving developers platform access and the ability to innovate and build on platform View Details
Keywords: Martha Lagace
- Article
The IT Transformation Health Care Needs
By: Nikhil R. Sahni, Robert S. Huckman, Anuraag Chigurupati and David M. Cutler
In recent years, health care organizations have made sizable investments in information technology. They’ve used their IT systems to replace paper records with electronic ones and to improve billing processes, thereby boosting revenue. But so far, IT has been of little... View Details
Keywords: Health Care and Treatment; Information Technology; Performance Improvement; Business Model
Sahni, Nikhil R., Robert S. Huckman, Anuraag Chigurupati, and David M. Cutler. "The IT Transformation Health Care Needs." Harvard Business Review 95, no. 6 (November–December 2017): 128–136.
- December 2010
- Case
Oral Rehydration Therapy
By: Nava Ashraf and Claire Qureshi
This case highlights the puzzlingly high rate of diarrhea-related child mortality in developing countries despite the existence of a simple, effective treatment: oral rehydration therapy (ORT). ORT treated extreme dehydration caused by diarrhea, which was a leading... View Details
Keywords: Health Care and Treatment; Innovation Strategy; Problems and Challenges; Developing Countries and Economies; Technological Innovation; Distribution Channels; Emerging Markets; Consumer Behavior; Performance Consistency; Performance Evaluation; Health Industry; Africa; Asia
Ashraf, Nava, and Claire Qureshi. "Oral Rehydration Therapy." Harvard Business School Case 911-035, December 2010. (Request a courtesy copy.)
- January 2025
- Technical Note
AI vs Human: Analyzing Acceptable Error Rates Using the Confusion Matrix
By: Tsedal Neeley and Tim Englehart
This technical note introduces the confusion matrix as a foundational tool in artificial intelligence (AI) and large language models (LLMs) for assessing the performance of classification models, focusing on their reliability for decision-making. A confusion matrix... View Details
Keywords: Reliability; Confusion Matrix; AI and Machine Learning; Decision Making; Measurement and Metrics; Performance
Neeley, Tsedal, and Tim Englehart. "AI vs Human: Analyzing Acceptable Error Rates Using the Confusion Matrix." Harvard Business School Technical Note 425-049, January 2025.