Publications

September 2002
Case

Align Technology, Inc.: Matching Manufacturing Capacity to Sales Demand

By: H. Kent Bowen and Jonathan P Groberg

Align Technology is a four-year-old medical products company that has invented a new product requiring new manufacturing processes. Demand for the new product has grown more slowly than initial forecasts predicted, and the cost structure is preventing the company from... View Details

Keywords: Health Care and Treatment; Collaborative Innovation and Invention; Problems and Challenges; Product; Forecasting and Prediction; Marketing Strategy; Sales; Demand and Consumers; Production; Health Industry

02 Jul 2019
Working Paper Summaries

Risk-Mitigating Technologies: The Case of Radiation Diagnostic Devices

Keywords: by Alberto Galasso and Hong Luo; Medical Devices & Supplies

May 2023 (Revised June 2023)
Supplement

Novartis (C): Reimagining Medicine

By: Ramon Casadesus-Masanell, Claudio Feser, Karolin Frankenberger and David Redaschi

This case unfolds around the first-ever approved personalized cancer treatment, how Novartis wrapped it into a new business model design, and how Novartis scaled it. Novartis — one of the largest pharmaceutical companies in the world — is, among other ventures,... View Details

Keywords: Health Testing and Trials; Health Care and Treatment; Business Model; Problems and Challenges; Pharmaceutical Industry; Switzerland

March 2023 (Revised June 2025)
Case

Close Concerns: Diabetes Research and Advocacy

By: Regina E. Herzlinger and Brian L. Walker

This case describes the Exit considerations of Kelly Close, HBS MBA, and founder of the primary distributor of diabetes newsletters. It is part of the fourth module in the Innovating in Health Care HBS MBA course, which contains cases of other health care firms that... View Details

Keywords: Diabetes; Health; Health Care; Health Care And Treatment; Health Care Outcomes; Health Care Industry; Knowledge Dissemination; Outcome or Result; Equality and Inequality; Business Model; Entrepreneurship

December 1998 (Revised March 1999)
Case

Disruptive Technology a Heartbeat Away: Ecton, Inc.

By: Clayton M. Christensen and Edward G Cape

Describes an innovating start-up company with a disruptive technology to the large, expensive echocardiography machines that leading cardiologists use to create images of heart functions for diagnostic purposes. Ecton's machine is small, cheap, portable, and can't... View Details

Keywords: Business Startups; Disruption; Machinery and Machining; Entrepreneurship; Innovation and Invention; Marketing; Product; Commercialization; Technology; Medical Devices and Supplies Industry

05 Dec 2006
First Look

First Look: December 5, 2006

Science Foundation. The developed platform offers an unprecedented view of the R&D-to-patenting innovation process and a close analysis of the strengths and limitations of the Industry R&D Survey. The files are linked through a... View Details

Keywords: Sean Silverthorne

2019
Working Paper

Soul and Machine (Learning)

By: Davide Proserpio, John R. Hauser, Xiao Liu, Tomomichi Amano, Alex Burnap, Tong Guo, Dokyun Lee, Randall Lewis, Kanishka Misra, Eric Schwarz, Artem Timoshenko, Lilei Xu and Hema Yoganarasimhan

Machine learning is bringing us self-driving cars, improved medical diagnostics, and machine translation, but can it improve marketing decisions? It can. Machine learning models predict extremely well, are scalable to “big data,” and are a natural fit to rich media... View Details

Keywords: Machine Learning; Technological Innovation; Marketing; AI and Machine Learning

SSRN

Read Now

15 Jul 2014
First Look

First Look: July 15

of investors―extracted from co-search patterns―in addressing long-standing benchmarking problems in finance. Publisher's link: http://ssrn.com/abstract=2171497 August 2013 Academy of Management Journal Exposed: Venture Capital, Competitor Ties, and Entrepreneurial... View Details

Keywords: Carmen Nobel

May 2023 (Revised June 2023)
Supplement

Novartis (B): Reimagining Medicine

By: Ramon Casadesus-Masanell, Claudio Feser, Karolin Frankenberger and David Redaschi

This case unfolds around the first-ever approved personalized cancer treatment, how Novartis wrapped it into a new business model design, and how Novartis scaled it. Novartis — one of the largest pharmaceutical companies in the world — is, among other ventures,... View Details

Keywords: Health Care and Treatment; Business Model; Production; Business Strategy; Pharmaceutical Industry

09 Apr 2013
First Look

First Look: April 9

Cases & Course Materials Harvard Business School Case 612-016 Lowell General Physician Hospital Organization This case focuses on the Alternative Quality Contract (AQC), a novel payment program designed to incentivize providers to deliver less costly, high... View Details

Keywords: Sean Silverthorne

06 Feb 2018
First Look

First Look at New Research and Ideas: February 6, 2018

Patent and Trademark Office (USPTO). Our findings illuminate the micro-foundations of innovation in firms by highlighting a trade-off between organizing patenting activity to maximize scope versus speed. Publisher's link:... View Details

December 2010
Case

Oral Rehydration Therapy

By: Nava Ashraf and Claire Qureshi

This case highlights the puzzlingly high rate of diarrhea-related child mortality in developing countries despite the existence of a simple, effective treatment: oral rehydration therapy (ORT). ORT treated extreme dehydration caused by diarrhea, which was a leading... View Details

Keywords: Health Care and Treatment; Innovation Strategy; Problems and Challenges; Developing Countries and Economies; Technological Innovation; Distribution Channels; Emerging Markets; Consumer Behavior; Performance Consistency; Performance Evaluation; Health Industry; Africa; Asia

September 2014
Case

FormPrint Ortho500

By: Frank V. Cespedes and Alisa Zalosh

The Senior Vice President of FormPrint's Medical Products business unit is considering issues raised by the upcoming introduction of a new 3D printing system, the Ortho500, which could print custom exoskeletal orthopedic splints, braces, and casts that conformed to a... View Details

Keywords: B2B Marketing; Technological Innovation; Market Entry and Exit; Marketing Strategy; Distribution Channels; Product Development; Medical Devices and Supplies Industry

04 Jun 2007
Research & Ideas

Is Health Care Making You Better—or Dead?

innovations and entrepreneurs in health services to spring up. But we don't. I have an acquaintance, Garrison Bliss, who is a Harvard Medical School doctor, and his brother-in-law is Norman Wu, a software... View Details

Keywords: by Sean Silverthorne; Health

March 2014
Teaching Note

Oral Rehydration Therapy

By: Nava Ashraf and Natalie Kindred

This Teaching Note accompanies the case "Oral Rehydration Therapy" (911-035). The case highlights the puzzlingly high rate of diarrhea-related child mortality in developing countries despite the existence of a simple, effective treatment: oral rehydration therapy... View Details

Keywords: Health Care and Treatment; Innovation Strategy; Problems and Challenges; Developing Countries and Economies; Technological Innovation; Distribution Channels; Emerging Markets; Consumer Behavior; Performance Consistency; Performance Evaluation; Health Industry; Africa; Asia

14 Dec 2021
Op-Ed

To Change Your Company's Culture, Don't Start by Trying to Change the Culture

something you fix Consider Vince Forlenza’s experience, as former CEO of medical technology maker Becton Dickinson, in developing a more innovative culture to meet the changing competitive landscape. He... View Details

Keywords: by Michael Beer

21 Jun 2010
Research & Ideas

Strategy and Execution for Emerging Markets

challenge is to understand local customer needs and produce localized products. In our book we discuss companies including GE, which has been innovating in the medical sector, and cellphone companies such as... View Details

Keywords: by Martha Lagace

January 2006 (Revised April 2007)
Case

General Electric Healthcare, 2006

By: Tarun Khanna and Elizabeth Raabe

In January 2006, Joe Hogan, head of General Electric (GE) Healthcare Technologies, prepared to step into William Castell's shoes as CEO of GE Healthcare, the world's leading manufacturer of diagnostic imaging equipment. In 2004, former CEO Jeff Immelt acquired Amersham... View Details

Keywords: Corporate Entrepreneurship; Cost vs Benefits; Growth and Development Strategy; Mergers and Acquisitions; Machinery and Machining; Global Range; Multinational Firms and Management; Product Design; Technological Innovation; Expansion; Value Creation; Business Subsidiaries; Medical Devices and Supplies Industry; Medical Devices and Supplies Industry

Article

Soul and Machine (Learning)

By: Davide Proserpio, John R. Hauser, Xiao Liu, Tomomichi Amano, Burnap Alex, Tong Guo, Dokyun (DK) Lee, Randall Lewis, Kanishka Misra, Eric Schwarz, Artem Timoshenko, Lilei Xu and Hema Yoganarasimhan

Machine learning is bringing us self-driving cars, medical diagnoses, and language translation, but how can machine learning help marketers improve marketing decisions? Machine learning models predict extremely well, are scalable to “big data,” and are a natural fit to... View Details

Keywords: Machine Learning; Marketing Applications; Knowledge; Technological Innovation; Core Relationships; Marketing; Applications and Software