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      • 2025
      • Working Paper

      Bringing Science to Market: Knowledge Foundations, Inventor-Founders, and Performance

      By: Justine Boudou and Maria Roche
      In this paper, we examine how a startup’s knowledge foundations—embedded in its core technology—influence its performance in the exit market. Using a dataset of 1,006 biomedicine startups founded between 2005 and 2015, we focus on two key factors: (1) the degree of... View Details
      Keywords: Firm Performance; Knowledge Foundations; Exits; Academic Startups; Inventor-founder; Specialized Scientific Knowledge; Competitive Advantage; Value Creation; Research; Information Publishing; Business Startups; Entrepreneurship
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      Boudou, Justine, and Maria Roche. "Bringing Science to Market: Knowledge Foundations, Inventor-Founders, and Performance." Harvard Business School Working Paper, No. 24-021, October 2023. (Revised February 2025.)
      • October 2023
      • Article

      Innovation on Wings: When Do Nonstop Flights Matter for Global Innovation?

      By: Dany Bahar, Prithwiraj Choudhury, Do Yoon Kim and Wesley Koo
      We study whether, when, and how better connectivity through nonstop flights leads to positive innovation outcomes for firms in the global context. Using unique data of all flights emanating from 5,015 airports around the globe from 2005 to 2015 and exploiting a... View Details
      Keywords: Nonstop Flights; Collaborative Innovation and Invention; Patents; Research and Development; Air Transportation Industry
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      Bahar, Dany, Prithwiraj Choudhury, Do Yoon Kim, and Wesley Koo. "Innovation on Wings: When Do Nonstop Flights Matter for Global Innovation?" Management Science 69, no. 10 (October 2023): 6202–6223.
      • 2023
      • Book

      Move Fast and Fix Things: The Trusted Leader's Guide to Solving Hard Problems

      By: Frances X. Frei and Anne Morriss
      Speed has gotten a bad name in business, much of it deserved. When Facebook made "Move fast and break things" an informal company motto, it fueled a widely held belief that we can either make progress or take care of people, one or the other. That a certain amount of... View Details
      Keywords: Leading Change; Performance Improvement; Problems and Challenges; Organizational Change and Adaptation; Organizational Culture
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      Frei, Frances X., and Anne Morriss. Move Fast and Fix Things: The Trusted Leader's Guide to Solving Hard Problems. Harvard Business Review Press, 2023.
      • October 14, 2023
      • Article

      Will Consumers Buy Selfish Self-Driving Cars?

      By: Julian De Freitas
      Keywords: AI and Machine Learning; Ethics; Technological Innovation; Safety; Auto Industry
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      De Freitas, Julian. "Will Consumers Buy Selfish Self-Driving Cars?" Wall Street Journal (October 14, 2023), C5.
      • September 2023 (Revised June 2024)
      • Case

      Kaspi.kz: Building Trust through Innovation

      By: Sandra J. Sucher, Fares Khrais and Marilyn Morgan Westner
      This case is written to help students explore how companies can maintain and develop trust while innovating, how to identify and respond effectively to warning signs that they may not be as trusted as they believe, and how being trusted can aid in expanding and growing... View Details
      Keywords: Growth and Development Strategy; Organizational Culture; Trust; Technology Adoption; Innovation and Invention; Banking Industry
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      Sucher, Sandra J., Fares Khrais, and Marilyn Morgan Westner. "Kaspi.kz: Building Trust through Innovation." Harvard Business School Case 324-022, September 2023. (Revised June 2024.)
      • September 2023
      • Technical Note

      Free and Open Source Software and Hardware

      By: Frank Nagle
      This technical note surveys the concepts of free and open source software and hardware. It introduces the concepts in general, providing a brief history of their development and numerous examples of how companies employ them in practice. Further, it identifies various... View Details
      Keywords: Corporate Strategy; Collaborative Innovation and Invention; Technological Innovation; Nonprofit Organizations; Competitive Strategy; Patents; Information Technology; Business Model; Open Source Distribution; Applications and Software; Information Technology Industry; Technology Industry
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      Nagle, Frank. "Free and Open Source Software and Hardware." Harvard Business School Technical Note 724-380, September 2023.
      • 2023
      • Working Paper

      Centralization and Organization Reproduction: Ethnic Innovation in R&D Centers and Satellite Locations

      By: William R. Kerr
      We study the relationship between firm centralization and organizational reproduction in satellite locations. For decentralized firms, the ethnic compositions of inventors in satellite locations mostly resemble their host cities, with little link to the inventor... View Details
      Keywords: Ethnicity; Business Offices; Research and Development; Innovation and Invention; Organizational Design
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      Kerr, William R. "Centralization and Organization Reproduction: Ethnic Innovation in R&D Centers and Satellite Locations." Harvard Business School Working Paper, No. 24-015, September 2023.
      • September 2023 (Revised November 2023)
      • Case

      Seeds of Innovation: GALY's Quest to Cultivate the Future of Agriculture in the Lab

      By: George Serafeim and Michael Norris
      In 2023, Luciano Bueno, CEO and founder of plant cell culture agriculture company GALY, was considering the best path forward for his company as he planned to pitch Series B investors. GALY, founded in 2019, aimed to produce cotton and other crops from cells grown in... View Details
      Keywords: Business Model; Green Technology; Goods and Commodities; Growth and Development Strategy; Science-Based Business; Entrepreneurship; Plant-Based Agribusiness; Business Startups; Decisions; Technological Innovation; Production; Agriculture and Agribusiness Industry; Technology Industry; Boston; Sao Paulo
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      Serafeim, George, and Michael Norris. "Seeds of Innovation: GALY's Quest to Cultivate the Future of Agriculture in the Lab." Harvard Business School Case 124-017, September 2023. (Revised November 2023.)
      • September 2023
      • Teaching Note

      Roche: ESG and Access to Healthcare

      By: George Serafeim
      Teaching Note for HBS Case No. 123-075. In May 2022, Roche Group, one of the largest healthcare companies in the world, hosted its first ESG investor event focused exclusively on its efforts to impact access to healthcare. While Roche had recently set an ambitious goal... View Details
      Keywords: ESG; Access To Care; Healthcare; Healthcare Access; Innovation; Social Impact; Affordable; Health Care and Treatment; Innovation and Invention; Product Development; Resource Allocation; Corporate Social Responsibility and Impact; Health Industry
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      Serafeim, George. "Roche: ESG and Access to Healthcare." Harvard Business School Teaching Note 124-028, September 2023.
      • September 2023
      • Teaching Note

      Nexleaf Analytics: Saving the World Using the Internet of Things

      By: Frank Nagle
      Teaching Note for HBS Case 722-414. View Details
      Keywords: Corporate Strategy; Collaborative Innovation and Invention; Technological Innovation; Nonprofit Organizations; Competitive Strategy; Patents; Expansion; Information Technology; Health Industry; Information Industry; Medical Devices and Supplies Industry; Technology Industry
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      Nagle, Frank. "Nexleaf Analytics: Saving the World Using the Internet of Things." Harvard Business School Teaching Note 724-381, September 2023.
      • September 2023 (Revised September 2024)
      • Technical Note

      Measuring and Managing Social Impact

      By: Brian Trelstad, Gerald Chertavian and Susan Pinckney
      A brief overview of how to measure social impact at nonprofits, social organizations, and impact investments. View Details
      Keywords: Analysis; Change; Transformation; Decision Making; Cost vs Benefits; Decision Choices and Conditions; Decisions; Forecasting and Prediction; Public Sector; Entrepreneurship; Social Entrepreneurship; Fairness; Entrepreneurial Finance; Governance; Governing and Advisory Boards; Policy; Innovation and Management; Knowledge Acquisition; Knowledge Use and Leverage; Goals and Objectives; Growth and Development Strategy; Growth Management; Management Analysis, Tools, and Techniques; Management Practices and Processes; Resource Allocation; Measurement and Metrics; Standards; Strength and Weakness; Mission and Purpose; Success; Performance; Performance Evaluation; Philanthropy and Charitable Giving; Strategic Planning; Programs; Risk and Uncertainty; Social Enterprise; Non-Governmental Organizations; Social Issues; United States
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      Trelstad, Brian, Gerald Chertavian, and Susan Pinckney. "Measuring and Managing Social Impact." Harvard Business School Technical Note 324-017, September 2023. (Revised September 2024.)
      • September 2023
      • Teaching Note

      Patagonia: 'Earth Is Now Our Only Shareholder'

      By: Brian Trelstad, Nien-hê Hsieh, Michael Norris and Susan Pinckney
      Teaching Note for HBS Case No. 323-057. Patagonia’s change of ownership from a privately held company to a perpetual purpose trust and 501(c)(4) nonprofit in order to use the company’s profit to fight the environmental crisis and be a model for future businesses. View Details
      Keywords: Trusts; Business Ventures; Business Organization; Family Business; Restructuring; Change; Disruption; Transition; Decision Making; Ethics; Values and Beliefs; Finance; Financial Management; Governance; Corporate Governance; Investment Activism; Innovation Leadership; Labor; Law; Common Law; Management; Goals and Objectives; Organizations; Corporate Social Responsibility and Impact; Organizational Change and Adaptation; Organizational Culture; Ownership; Ownership Type; Family Ownership; Private Ownership; Social Enterprise; Nonprofit Organizations; Society; Social Issues; Wealth and Poverty; Value; Value Creation; Apparel and Accessories Industry; United States
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      Trelstad, Brian, Nien-hê Hsieh, Michael Norris, and Susan Pinckney. "Patagonia: 'Earth Is Now Our Only Shareholder'." Harvard Business School Teaching Note 324-003, September 2023.
      • September 2023
      • Background Note

      Amager Bakke: Municipal Waste to Energy

      By: Willy Shih, Michael W. Toffel and Kelsey Carter
      This background note describes the Amager Bakke waste-to-energy (WtE) plant in Copenhagen, which merges traditional waste incineration with a combined heat and power (CHP) plant and air pollution control (scrubbing) technology, and had plans to add carbon dioxide (CO2)... View Details
      Keywords: Decarbonization; Innovation; Innovation Focused Strategy; Environmental Operations; Circular; Waste Heat Recovery; Waste Management; Carbon Regulation; Buildings and Facilities; Energy Generation; Environmental Sustainability; Pollution; Climate Change; Wastes and Waste Processing; Innovation Leadership; Innovation Strategy; Energy Industry; Denmark; Netherlands; Europe; European Union
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      Shih, Willy, Michael W. Toffel, and Kelsey Carter. "Amager Bakke: Municipal Waste to Energy." Harvard Business School Background Note 624-040, September 2023.
      • September 2023
      • Case

      FoodCloud: Tackling Food Insecurity and Climate Change in One Bite

      By: Brian Trelstad and Emer Moloney
      In 2013, Aoibheann O’Brien and Iseult Ward founded FoodCloud, a non-profit social enterprise that aimed to address food waste and food insecurity issues. Through its technology platform, Foodiverse, FoodCloud connected surplus food from retailers with community groups... View Details
      Keywords: Nonprofit Organizations; Expansion; Technological Innovation; Environmental Sustainability; Social Issues; Growth and Development Strategy; Green Technology Industry; Agriculture and Agribusiness Industry; Food and Beverage Industry; Republic of Ireland; Europe
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      Trelstad, Brian, and Emer Moloney. "FoodCloud: Tackling Food Insecurity and Climate Change in One Bite." Harvard Business School Case 324-031, September 2023.
      • September 2023 (Revised January 2024)
      • Case

      AI21 Labs in 2023: Strategy for Generative AI

      By: David Yoffie, Orna Dan and Elena Corsi
      Israeli generative artificial intelligence company AI21 Labs was founded in 2017 to realize the vision of true machine intelligence. It sought to reinvent writing and reading and in 2020 it launched Wordtune, an app using GenAI software to offer alternate text... View Details
      Keywords: Decision Making; AI and Machine Learning; Innovation Strategy; Growth and Development Strategy; Applications and Software; Competitive Strategy; Technology Industry; Israel
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      Yoffie, David, Orna Dan, and Elena Corsi. "AI21 Labs in 2023: Strategy for Generative AI." Harvard Business School Case 724-383, September 2023. (Revised January 2024.)
      • September 2023 (Revised June 2024)
      • Case

      CyberArk: Fearlessly Forward in a Digital World

      By: David B. Yoffie and Daniela Beyersdorfer
      CyberArk was a leader in privileged access management and was an emerging leader in security identity. This case explores strategies in cybersecurity and whether big bets are needed to become a global leader. View Details
      Keywords: Cybersecurity; Strategy; Technological Innovation; Technology Industry
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      Yoffie, David B., and Daniela Beyersdorfer. "CyberArk: Fearlessly Forward in a Digital World." Harvard Business School Case 724-382, September 2023. (Revised June 2024.)
      • September 2023 (Revised July 2024)
      • Case

      Going Mobile-First? The Digital Transformation of Davivienda Bank in Colombia

      By: Jorge Tamayo and Jenyfeer Martinez Buitrago
      Set in 2017, this case describes the digital transformation strategy of Davivienda—a leading player in Colombia’s commercial banking and one of the companies belonging to Grupo Bolívar, a major Colombian financial conglomerate. The case also describes the pioneer role... View Details
      Keywords: Change Management; Transformation; Decision Choices and Conditions; Information Technology; Digital Strategy; Digital Transformation; Internet and the Web; Mobile and Wireless Technology; Innovation and Management; Innovation Strategy; Growth and Development Strategy; Business Strategy; Banking Industry; Latin America; Central America; South America; Colombia
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      Tamayo, Jorge, and Jenyfeer Martinez Buitrago. "Going Mobile-First? The Digital Transformation of Davivienda Bank in Colombia." Harvard Business School Case 724-389, September 2023. (Revised July 2024.)
      • September 2023 (Revised April 2024)
      • Case

      Atomwise: Strategic Opportunities in AI for Pharma

      By: Satish Tadikonda
      Abraham Heifets and his co-founder, Izhar Wallach, had founded Atomwise to develop i) an AI engine to transform drug discovery by creating better medicines faster, and ii) a machine learning-based discovery engine that combined the power of convolutional neural... View Details
      Keywords: Business Model; Business Startups; AI and Machine Learning; Science-Based Business; Technological Innovation; Biotechnology Industry; Pharmaceutical Industry
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      Tadikonda, Satish. "Atomwise: Strategic Opportunities in AI for Pharma." Harvard Business School Case 824-043, September 2023. (Revised April 2024.)
      • September 2023
      • Supplement

      Fighting the Battle of the Bulge—Evaluating Do Good/Do Well Innovations in Morbid Obesity Treatment

      By: Regina E. Herzlinger
      This PowerPoint accompanies Regina E. Herzlinger's "Fighting the Battle of the Bulge – Evaluating Do Good/Do Well Innovations in Morbid Obesity Treatment" teaching note (HBS Case No.324-013) and is designed for instructors to use in the classroom when teaching this... View Details
      Keywords: Health Care Delivery; Obesity; Weight Loss; Innovation and Invention; Innovation and Management; Health Care and Treatment; Medical Specialties; Health Industry
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      Herzlinger, Regina E. "Fighting the Battle of the Bulge—Evaluating Do Good/Do Well Innovations in Morbid Obesity Treatment." Harvard Business School PowerPoint Supplement 324-016, September 2023.
      • September 2023
      • Teaching Note

      Fighting the Battle of the Bulge—Evaluating Do Good/Do Well Innovations in Morbid Obesity Treatment

      By: Regina E. Herzlinger
      Teaching Note for HBS Case No. 304-009. The case is part of the first module of the Innovating in Health Care course. Its purpose is to demonstrate how to evaluate the “do good” and do well” potential of a health care innovation. View Details
      Keywords: Innovation In Healthcare Delivery; Innovation; Obesity; Digital Health; Weight Loss; Health Care and Treatment; Innovation and Management; Business Model; Medical Specialties; Mission and Purpose; Health Industry
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      Herzlinger, Regina E. "Fighting the Battle of the Bulge—Evaluating Do Good/Do Well Innovations in Morbid Obesity Treatment." Harvard Business School Teaching Note 324-013, September 2023.
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