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  • Article

Lessons From Hollywood: A New Approach To Funding R&D

By: Gary P. Pisano and Andrew W. Lo
Companies find it increasingly difficult to justify long-term, risky R&D investments—particularly in science-based fields such as biotechnology, advanced materials, and energy. We argue in this article that the traditional venture model has limits for such investments... View Details
Keywords: Financial Innovation; Financial Strategy; Project Management; R＆D; Start-up; Innovation Strategy; Business Model; Research and Development; Financial Management; Risk Management; Strategy
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  • January 2011 (Revised July 2012)
  • Case

Arcadia Biosciences: Seeds of Change (Abridged)

By: Arthur A. Daemmrich
Arcadia Biosciences is seeking to introduce genetically modified rice to China that will lower farmers' costs and generate environmental benefits through reduced greenhouse gas emissions. The case describes challenges facing this small agricultural biotechnology... View Details
Keywords: Plant-Based Agribusiness; Intellectual Property; Genetics; Environmental Sustainability; Science-Based Business; Climate Change; Agriculture and Agribusiness Industry; Biotechnology Industry; China
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  • September–October 2020
  • Article

The Past, Present, and (Near) Future of Gene Therapy and Gene Editing

By: Julia Pian, Amitabh Chandra and Ariel Dora Stern
Emerging gene therapy and gene-editing technologies will have a growing impact on patient lives and health-care delivery. We analyzed a decade of data on clinical trials and venture capital investments to understand the likely trajectory of genetically focused... View Details
Keywords: Gene Therapy; Gene Editing; Impact; Health Care and Treatment; Technological Innovation; Health Testing and Trials; Venture Capital; Change
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  • April 2013
  • Article

Using the Crowd as an Innovation Partner

By: Kevin J. Boudreau and Karim R. Lakhani
More and more organizations are turning to crowds for help in solving their most vexing innovation and research questions, but managers remain understandably cautious. It seems risky and even unnatural to push problems out to vast groups of strangers distributed around... View Details
Keywords: Innovation and Management; Research and Development
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  • December 1998 (Revised May 1999)
  • Case

PlaceWare: Issues in Structuring a Xerox Technology Spinout

Xerox has established a process to spin out technologies it develops that do not fit with its current business needs. To structure these "spinouts," a number of issues arise on how to treat people and intellectual property. PlaceWare is the first technology to go... View Details
Keywords: Technology; Commercialization; Corporate Entrepreneurship; Intellectual Property
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  • 14 Aug 2012
  • First Look

First Look: August 14

http://www.hbs.edu/research/pdf/13-010.pdf IP Modularity: Profiting from Innovation by Aligning Product Architecture with Intellectual Property Authors:Joachim Henkel, Carliss Y. Baldwin, and Willy C. Shih... View Details
Keywords: Sean Silverthorne
  • June 2024
  • Teaching Note

Numenta in 2020: The Future of AI

By: David B. Yoffie
In 2020, Numenta’s co-founder, Jeff Hawkins, completed his pathbreaking research on artificial intelligence. His co-founder and CEO, Donna Dubinsky, had to find a business model to monetize the technology. This teaching note explores the challenges of building a... View Details
Keywords: Artificial Intelligence; Monetization; Strategy; Intellectual Property; AI and Machine Learning; Business Model; Entrepreneurship; Technology Industry
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  • 10 Dec 2013
  • First Look

First Look: December 10

Brands The case explores the collateralization of intellectual property in a loan agreement between a highly leveraged apparel company and a large U.S. bank. Leveraging intangibles in the credit market is a... View Details
Keywords: Sean Silverthorne
  • Research Summary

Knowledge flows and capability acquisition

By: Willy C. Shih
Technological advancements are a major source of improvement in competiveness, and a firm’s incentives to invest are diminished when the knowledge generated is involuntarily dispersed to competitors.  While intellectual property rights can moderate this flow to the... View Details
Keywords: Knowledge Aspects Of Strategy; Knowledge Management; Knowledge Spillovers; Knowledge Acquisition; Manufacturing Industry; Biotechnology Industry; Technology Industry; United States; China

    Patent Trolls: Evidence and Proposed Solutions

     

    The Growing Problem of Patent Trolling • SCIENCE • VIDEO

    View Details

    • May 2006
    • Case

    A123Systems

    By: H. Kent Bowen, Kenneth P Morse and Douglass Cannon
    A 123Systems was a young company that was founded on basic materials science research at the Massachusetts Institute of Technology. A co-founder of the company, Yet-Ming Chiang, was a full professor at MIT and served as scientific adviser. Intellectual property based... View Details
    Keywords: Intellectual Property; Business Startups; Research and Development; Commercialization; Technological Innovation; Science-Based Business; Product Development; Battery Industry; Electronics Industry; Massachusetts
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    • July 2008 (Revised October 2008)
    • Case

    Fidelity Investments' Charitable Gift Fund (A)

    By: Robert C. Pozen
    Deborah Pege, an attorney at Fidelity Investments, needs to decide whether Fidelity should attempt to patent business processes involved with its new charitable gift fund. The case explores the conditions that must be satisfied in order to receive a patent and raises... View Details
    Keywords: Investment Funds; Patents; Business Processes; Value
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    • March 2022 (Revised July 2022)
    • Case

    Nexleaf Analytics: Saving the World Using the Internet of Things

    By: Frank Nagle
    In 2019, a decade after co-founding Nexleaf Analytics, CEO Nithya Ramanathan faced an important decision that would impact the ability of the small, but growing, not-for-profit organization to thrive for another decade. Their sensor technologies and big data analytics... View Details
    Keywords: Corporate Strategy; Collaborative Innovation and Invention; Technological Innovation; Nonprofit Organizations; Competitive Strategy; Patents; Expansion; Information Technology; Health Industry; Information Industry; Medical Devices and Supplies Industry; Technology Industry
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    • October 1987 (Revised October 1998)
    • Case

    CVD, Inc. vs. A.S. Markham Corp. (A)

    Describes the legal odyssey of two engineers who left their old employer to start a company that was directly competitive. The issues include employment contracts, technology licenses, antitrust, trade secrets, and confidential information. Provides a good opportunity... View Details
    Keywords: Business Strategy; Human Resources; Contracts; Knowledge Use and Leverage; Intellectual Property; Ethics; Legal Liability; Business Startups; Monopoly
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    • 07 Sep 2007
    • Working Paper Summaries

    Diversification of Chinese Companies: An International Comparison

    Keywords: by Joseph P.H. Fan, Jun Huang, Felix Oberholzer-Gee, Troy D. Smith & Mengxin Zhao
    • 23 Aug 2006
    • Working Paper Summaries

    Capturing Benefits from Tomorrow’s Technology in Today’s Products: The Effect of Absorptive Capacity

    Keywords: by Daniel Snow; Technology
    • 01 Nov 2016
    • Working Paper Summaries

    Patent Disclosures and Standard-Setting

    Keywords: by Josh Lerner, Haris Tabakovic, and Jean Tirole

      Winning in Emerging Markets: A Roadmap for Strategy and Execution

      Most books thus far on emerging markets are either investing-oriented (Mobius, Pereiro), or country - or market-specific (Farrell, Lindahl), or descriptive (Friedman, van Agtmael). No book has definitively targeted the corporate strategists who need a practical... View Details

      • February 2022 (Revised September 2022)
      • Case

      InstaDeep: AI Innovation Born in Africa (A)

      By: Shikhar Ghosh and Esel Çekin
      Karim Beguir and Zohra Slim were the co-founders of InstaDeep, a deep tech startup focusing on artificial intelligence (AI) solutions. Instadeep was one of the few companies globally that were partnering with DeepMind, an AI subsidiary of Google [Alphabet Inc.].... View Details
      Keywords: AI; Artificial Intelligence; Entrepreneurship; Operations; Business Subsidiaries; Brands and Branding; Innovation and Invention; Growth and Development Strategy; AI and Machine Learning; Technology Industry; Africa
      Related
      • August 2009 (Revised April 2012)
      • Case

      Genzyme's CSR Dilemma: How to Play its HAND

      By: Christopher A. Bartlett, Tarun Khanna and Prithwiraj Choudhury
      Genzyme, a global biotechnology company, launches a program to develop therapies for neglected diseases (e.g., malaria, TB), giving away the intellectual property. This case focuses on the decision of which diseases, which partnerships, and which markets should... View Details
      Keywords: Global Strategy; Health Care and Treatment; Intellectual Property; Corporate Social Responsibility and Impact; Partners and Partnerships; Research and Development; Biotechnology Industry
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