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  • All HBS Web  (1,054)
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    • Research  (628)
    • Events  (1)
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  • 10 Oct 2017
  • First Look

First Look at New Research and Ideas, October 10, 2017

in the diabetic space, became MannKind’s marketing partner and helped launch Afrezza in February, 2015. Although the drug had a black box warning and required doctors to perform a lung View Details
Keywords: Sean Silverthorne
  • 03 Oct 2017
  • First Look

First Look at Research and Ideas, October 3, 2017

substantial improvements in child health as measured by child weight and height. Our key test of rational addiction is implemented by informing a subset of households about a... View Details
Keywords: by Sean Silverthorne
  • April 2014 (Revised July 2015)
  • Case

Sanofi Pasteur: The Dengue Vaccine Dilemma

By: V. Kasturi Rangan, David E. Bloom, Vincent Dessain and Emilie Billaud
In 2012, Sanofi Pasteur was racing to develop a vaccine against dengue, a mosquito-borne disease, and was evaluating this product in a Phase IIb trial conducted with school children in Thailand. But while the candidate vaccine met the high safety expectations and a... View Details
Keywords: Health Testing and Trials; Product Launch; Market Entry and Exit; Emerging Markets; Pharmaceutical Industry; France
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Rangan, V. Kasturi, David E. Bloom, Vincent Dessain, and Emilie Billaud. "Sanofi Pasteur: The Dengue Vaccine Dilemma." Harvard Business School Case 514-074, April 2014. (Revised July 2015.)
  • 2006
  • Chapter

BioRisk: interleukin-2 from laboratory to market in the United States and Germany

By: Arthur A. Daemmrich
Keywords: Product Development; Risk and Uncertainty; Health Testing and Trials; Pharmaceutical Industry; Biotechnology Industry; United States; Germany
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Daemmrich, Arthur A. "BioRisk: interleukin-2 from laboratory to market in the United States and Germany ." In The Risks of Medical Innovation: Risk Perception and Assessment in Historical Context, edited by Thomas Schlich and Ulrich Tröhler, 242–261. Routledge, 2006.
  • February 2009
  • Case

Avid Radiopharmaceuticals: The Venture Debt Question

By: Matthew Rhodes-Kropf and Ann Leamon
The CEO of a promising biotech company must decide how to respond to the macro-economic slump of late 2008. He had planned to pursue an aggressive schedule, moving the firm's Alzheimer's and Parkinson's disease imaging compounds through clinical trials and into the... View Details
Keywords: Financial Crisis; Entrepreneurship; Borrowing and Debt; Venture Capital; Financial Management; Investment; Health Testing and Trials; Expansion; Biotechnology Industry; Pharmaceutical Industry
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Rhodes-Kropf, Matthew, and Ann Leamon. "Avid Radiopharmaceuticals: The Venture Debt Question." Harvard Business School Case 809-086, February 2009.
  • 16 Oct 2013
  • Op-Ed

Response to Readers: Combating Climate Change with Nuclear Power and Fracking

With more than 7,500 views and 180-plus tweets, I want to thank everyone for taking the time to read the original HBS Working Knowledge piece, The Case for Combating Climate Change with Nuclear Power and Fracking, and, in particular, for sharing your thoughts with one... View Details
Keywords: by Joe Lassiter; Energy; Utilities
  • November 2023 (Revised April 2024)
  • Case

BiomX: Bringing Phage Back to the Stage

By: Paul A. Gompers, Elie Ofek, Orna Dan and Emilie Billaud
In the spring of 2023, and following the favorable results of a trial involving its phage cocktail for treating lung infections among cystic fibrosis (CF) patients, the leadership of BiomX had several critical issues to wrestle with. First, given its precarious... View Details
Keywords: Working Capital; Financing and Loans; Health Testing and Trials; Product Development; Research and Development; Science-Based Business; Commercialization; Biotechnology Industry; Pharmaceutical Industry
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Gompers, Paul A., Elie Ofek, Orna Dan, and Emilie Billaud. "BiomX: Bringing Phage Back to the Stage." Harvard Business School Case 524-051, November 2023. (Revised April 2024.)
  • 01 Aug 2017
  • First Look

First Look at New Research and Ideas, August 1

Abstract—Objective: Assess whether a commitment contract informed by behavioral economics leads to persistent virologic suppression among HIV-positive patients with poor antiretroviral therapy (ART) adherence. Design: Single-center pilot randomized clinical View Details
Keywords: Sean Silverthorne
  • 16 May 2017
  • First Look

First Look at New Ideas and Research, May 16

health of the enterprise rather than near-term returns to its shareholders. Their model would refocus companies’ attention to innovation, strategic renewal, and investment in the future. Publisher's link:... View Details
Keywords: Re: Multiple Faculty
  • 2008
  • Article

Entrepreneurial Ventures and Whole-body Donations: A Regional Perspective from the United States

By: Michel Anteby and Mikell Hyman

Human cadavers are crucial to medical science. While the debate on how to secure sufficient cadavers has focused primarily on donors' behaviors, procuring organizations' roles in increasing donations remain less explored. The United States offers a unique setting in... View Details

Keywords: Entrepreneurship; Behavior; Programs; Nonprofit Organizations; Business Ventures; Health Testing and Trials; Demand and Consumers; Supply Chain; For-Profit Firms; Organizations; Training; United States
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Anteby, Michel, and Mikell Hyman. "Entrepreneurial Ventures and Whole-body Donations: A Regional Perspective from the United States." Social Science & Medicine 66, no. 4 (2008): 963–969.
  • 05 Sep 2017
  • First Look

First Look at New Research and Ideas, September 5, 2017

that influences billions of people globally. Although the health and environmental costs of air pollution are well known, the present research investigates its ethical costs. We propose that air pollution... View Details
Keywords: Sean Silverthorne
  • 12 Aug 2019
  • Working Paper Summaries

Case Histories of Significant Medical Advances

Keywords: by Amar Bhidé, Srikant M. Datar, and Katherine Stebbins
  • 06 Feb 2018
  • First Look

First Look at New Research and Ideas: February 6, 2018

communities) and the moderating effects of team leader experience. We test our moderated mediation model in a sample of 121 teams that filed patents in a Fortune 50 company’s India R&D center between... View Details
  • 26 Sep 2017
  • First Look

First Look at New Research and Ideas, September 26, 2017

article proposes that the review process initially be adopted on a pilot basis. Publisher's link: https://www.hbs.edu/faculty/Pages/item.aspx?num=53264 September 2017 Health Affairs Narrow Networks on the View Details
Keywords: Sean Silverthorne
  • 28 May 2019
  • Research & Ideas

Investor Lawsuits Against Auditors Are Falling, and That's Bad News for Capital Markets

mistake made. Our tests show that previously when there have been serious restatements of financials, those mistakes would lead to a certain number of lawsuits being filed and a certain settlement amount... View Details
Keywords: by Martha Lagace; Financial Services; Accounting
  • 17 Oct 2017
  • First Look

First Look at New Research and Ideas, October 17, 2017

patient satisfaction, and problems with patient safety. Nearly all U.S. health care organizations have used similar evidence to justify their investments in safety and quality.... View Details
Keywords: Sean Silverthorne
  • 23 May 2017
  • First Look

First Look at New Ideas and Research: May 23, 2017

about the causes of regional variations in health care expenditures. We use vignettes from patient and physician surveys linked to fee-for-service Medicare expenditures to test... View Details
Keywords: Carmen Nobel
  • April 2019 (Revised January 2025)
  • Case

Clear Link Technologies, LLC: Driving Sales with Peer Effects

By: Christopher Stanton, Richard Saouma and Olivia Hull
The importance of a good peer or coworker is widely discussed, but understanding the glue that makes coworkers valuable is less understood. This case sheds light on the importance of peers and the practices and environments that make a group greater than the sum of its... View Details
Keywords: Talent and Talent Management; Interactive Communication; Experience and Expertise; Decision Making; Training; Design; Compensation and Benefits; Knowledge Acquisition; Knowledge Sharing; Human Capital; Working Conditions; Measurement and Metrics; Outcome or Result; Performance; Performance Improvement; Research; Sales; Salesforce Management; Motivation and Incentives; Telecommunications Industry; Utah; United States
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Stanton, Christopher, Richard Saouma, and Olivia Hull. "Clear Link Technologies, LLC: Driving Sales with Peer Effects." Harvard Business School Case 819-072, April 2019. (Revised January 2025.)
  • 24 Apr 2018
  • First Look

First Look at New Research and Ideas, April 24, 2018

and financial outcomes. The study complements financial education with (1) financial incentives on a financial literacy test to affect participant motivation, (2) financial goal setting to provide a... View Details
Keywords: Sean Silverthorne
  • 13 Jul 2020
  • Research & Ideas

Merck CEO Ken Frazier Discusses a COVID Cure, Racism, and Why Leaders Need to Walk the Talk

criminal justice reform, other issues like that, health care reform, but the nexus between corporate America and what Black America needs and the most, in my opinion, is... View Details
Keywords: by Staff; Pharmaceutical
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