Publications

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2025
Working Paper

Warnings and Endorsements: Improving Human-AI Collaboration in the Presence of Outliers

By: Matthew DosSantos DiSorbo, Kris Ferreira, Maya Balakrishnan and Jordan Tong

Problem definition: While artificial intelligence (AI) algorithms may perform well on data that are representative of the training set (inliers), they may err when extrapolating on non-representative data (outliers). How can humans and algorithms work together to make... View Details

Keywords: AI and Machine Learning; Decision Choices and Conditions

January 2024 (Revised April 2024)
Case

Target Malaria: Editing Mosquitoes through Gene Drives

By: Shikhar Ghosh and Shweta Bagai

Target Malaria, a non-profit research consortium, is exploring the application of CRISPR-Cas9 gene editing technology to combat malaria in Sub-Saharan Africa. Its approach uses gene drives, a revolutionary tool, to suppress the population of malaria-carrying... View Details

Keywords: Health Disorders; Technological Innovation; Nonprofit Organizations; Business Strategy; Genetics; Ethics; Governing Rules, Regulations, and Reforms; United States; United Kingdom; Burkina Faso; Africa

January 2024
Supplement

Buurtzorg

By: Ethan Bernstein and Tatiana Sandino

As co-founders of home nursing company Buurtzorg, Jos de Blok and Gonnie Kronenberg prized both self-management and organizational learning. Buurtzorg’s 10,000 nurses across 950 neighborhood nursing teams in the Netherlands were empowered to manage themselves, both in... View Details

Keywords: Organizational Design; Management Style; Business Model; Knowledge Dissemination; Learning; Organizational Culture; Health Industry; Netherlands

2024
Report

Overcoming Barriers to Resolving Gaza and Beyond

By: James K. Sebenius

As of early January 2024, discussion of the Gaza war heavily focuses on its humanitarian costs, cease fire possibilities, hostage prospects, and “day after” options. Yet what longer-term strategy guides actions on these vital issues while offering a more positive... View Details

Keywords: Negotiation; War; International Relations; Israel; Middle East

January 2024 (Revised October 2024)
Case

DO & CO: Crafting Luxury in the Fast Lane (A)

By: Juan Alcácer, Esel Cekin, Michael Lee and Noah Roberson

In July 2023, Attila Dogudan, the chairman of DO & CO, a renowned international catering firm, found himself in a deep conversation with his two sons about a potential new venture: catering for the Las Vegas Grand Prix, a significant step beyond their 31-year history... View Details

Keywords: Decision Choices and Conditions; Health Pandemics; Opportunities; Corporate Strategy; Luxury; Food and Beverage Industry; Las Vegas

January 19, 2024
Article

Value-Based Health Care Can Transform the Treatment of Patients with Substance Use Disorder

By: Robert S. Kaplan and Sarah E. Wakeman

U.S. overdose deaths currently exceed 100,000 per year. New facilities, known as bridge clinics, are broadening access to high-quality care by offering outpatient substance use disorder (SUD) treatment with few access barriers. But many of the critical services offered... View Details

Keywords: Health Care and Treatment; Cost; Adoption

2024
Working Paper

Contributing to Growth? The Role of Open Source Software for Global Startups

By: Nataliya Langburd Wright, Frank Nagle and Shane Greenstein

How does participating in open source software (OSS) communities spur entrepreneurial growth? To address this question, we analyze novel data matching accounts from GitHub—the largest OSS hosting platform—to the universe of global software venture-backed firms... View Details

Keywords: Applications and Software; Open Source Distribution; Entrepreneurship; Business Growth and Maturation; Human Capital; Valuation; Corporate Strategy

SSRN

January 2024 (Revised April 2024)
Teaching Note

Somatus: Value-Based Kidney Care (A) & (B)

By: Ariel D. Stern, Robert S. Huckman and Sarah Mehta

This teaching note accompanies case no. 622-009 and 622-045 (Somatus: Value-Based Kidney Care, A and B). View Details

Keywords: Business Startups; Disruption; Entrepreneurship; Health Care and Treatment; Health Disorders; Medical Specialties; Innovation and Invention; Disruptive Innovation; Management; Business Strategy; Value Creation; Health Industry; United States; Virginia

January 2024
Background Note

Evaluating Innovations in the Organization of Primary Care: What Type of Innovation Is It and How Well Does It Align with the Six Factors?

By: Regina E. Herzlinger and James Wallace

How can we evaluate if innovative health care ventures can do good—benefit society—and do well—become financially viable? This question is the topic of the first module in the Innovating in Health Care course book.

This note and "Health Stop (A): What Type... View Details

Keywords: Business Model; Health Care and Treatment; Collaborative Innovation and Invention; Mission and Purpose; Alignment; Health Industry

January 2024
Case

Vibrant Health

By: Henry McGee and Sarah Mehta

This case is about nutritional supplements company Vibrant Health, among the 100 largest Black-owned businesses in the U.S. After acquiring the company from its white founder in 2007, co-owners Ted and Paige Parker significantly grew its sales. Set in September 2023,... View Details

Keywords: Business Ventures; Race; Entrepreneurship; Nutrition; Ownership; Business Strategy; Growth and Development Strategy; Leadership; Sales; Food and Beverage Industry; Food and Beverage Industry; Eastern United States

January 2024
Technical Note

The ICARUS Principles: What It Takes to Tackle the World

By: Debora L. Spar and Julia M. Comeau

Over the course of the 20th century, most of the world’s major multinational corporations framed their mission around Milton Friedman’s famous mantra: that the sole purpose of the firm is to maximize its shareholders’ profits. Recently, however, growing numbers of... View Details

Keywords: Purpose; Mission; Social Business; Corporate Social Responsibility and Impact; Mission and Purpose; Social Enterprise; For-Profit Firms

January 2024
Case

Sprouts Farmers Market

By: Rajiv Lal, Forest L. Reinhardt and Natalie Kindred

Sprouts Farmers Markets (Sprouts) is a Phoenix, Arizona-based chain of 400-plus natural foods stores in 23 U.S. states and $6.4 billion in sales as of 2022. In its product assortment, brand image, and store environment, Sprouts emphasizes freshness, health, innovation,... View Details

Keywords: Business Model; Growth and Development Strategy; Brands and Branding; Strategic Planning; Sales; Business Strategy; Expansion; Product Positioning; Marketing Strategy; Competition; Retail Industry; United States; Arizona

January 2024
Article

A Cost Model for a Low Threshold Clinic Treating Opioid Use Disorder

By: Sarah E. Wakeman, Elizabeth Powell, Syed Shehab, Grace Herman, Laura Kehoe and Robert S. Kaplan

The US fee-for-service payment system under-reimburses clinics offering access to comprehensive treatments for opioid use disorder (OUD). The funding shortfall limits a clinic’s ability to expand and improve access, especially for socially marginalized patients with... View Details

Keywords: Health Care and Treatment; Cost; Equality and Inequality; Health Industry

January 2024
Article

Cost of Exempting Sole Orphan Drugs from Medicare Negotiation

By: Matthew Vogel, Olivia Zhao, William B. Feldman, Amitabh Chandra, Aaron S. Kesselheim and Benjamin N. Rome

Importance: The Inflation Reduction Act (IRA) requires Medicare to negotiate prices for some high-spending drugs but exempts drugs approved solely for the treatment of a single rare disease.
Objective: To estimate Medicare spending and global... View Details

Keywords: Health Care and Treatment; Insurance; Price; Health Industry

January 2024
Article

Population Interference in Panel Experiments

By: Kevin Wu Han, Guillaume Basse and Iavor Bojinov

The phenomenon of population interference, where a treatment assigned to one experimental unit affects another experimental unit’s outcome, has received considerable attention in standard randomized experiments. The complications produced by population interference in... View Details

Keywords: Outcome or Result; Research; Situation or Environment

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January–February 2024
Article

Shared Service Delivery Can Increase Client Engagement: A Study of Shared Medical Appointments

By: Ryan W. Buell, Kamalini Ramdas, Nazlı Sönmez, Kavitha Srinivasan and Rengaraj Venkatesh

Problem Definition: Clients and service providers alike often consider one-on-one service delivery to be ideal, assuming – perhaps unquestioningly – that devoting individualized attention best improves client outcomes. In contrast, in shared service delivery, clients... View Details

Keywords: Health Care and Treatment; Customer Satisfaction; Outcome or Result; Performance Improvement

January 2024
Article

Subset Scanning for Multi-Trait Analysis Using GWAS Summary Statistics

By: Rui Cao, Evan Olawsky, Edward McFowland III, Erin Marcotte, Logan Spector and Tianzhong Yang

Multi-trait analysis has been shown to have greater statistical power than single-trait analysis. Most of the existing multi-trait analysis methods only work with a limited number of traits and usually prioritize high statistical power over identifying relevant traits,... View Details

Keywords: Mathematical Methods; Health Disorders