Publications

Profile

Prineeta Kulkarni

Prineeta Kulkarni originally "dreamed of becoming a scientist." She completed a dual biotechnology BS/MS at the University of Pune, but when it came time to launch her career, she shifted direction. "I wanted to see the... View Details

Keywords: Healthcare/Biotech; Nonprofit/Government/Education

January 2001
Case

Abgenix and the XenoMouse

By: Robert J. Dolan

Abgenix has a unique method for generating antibodies useful in treating a number of diseases, including cancer. In early 2000, the company's cancer has performed very well in animal testing and is moving to early stage human testing. Abgenix must decide whether to... View Details

Keywords: Product Development; Marketing Strategy; Health Testing and Trials; Risk and Uncertainty; Technological Innovation; Innovation Strategy; Science-Based Business; Biotechnology Industry

October 2007 (Revised July 2013)
Case

Vertex Pharmaceuticals and the Cystic Fibrosis Foundation: Venture Philanthropy Funding for Biotech

By: Robert F. Higgins, Sophie LaMontagne and Brent Kazan

In 2001, Vertex Pharmaceuticals Incorporated acquired the San Diego-based biotech company, Aurora Biosciences. The combination of Vertex's and Aurora's technologies would improve the flow of novel drug candidates into development. However, several questions related to... View Details

Keywords: Philanthropy; Philanthropy Funding; Innovation; Funding Model; Venture Capital; Partners and Partnerships; Financing and Loans; Investment Funds; Acquisition; Philanthropy and Charitable Giving; Biotechnology Industry; Biotechnology Industry; San Diego

02 Dec 2002
Research & Ideas

The Secret of How Microsoft Stays on Top

industry or the biotechnology industry? Both industries share similarities with software, in that firms codify their intellectual property into libraries that can be reused and extended over time. But do we observe the same dynamics in... View Details

Keywords: by Sean Silverthorne

12 Apr 2022
Blog Post

The Many Languages of Medicine to Impact Care Delivery

their suffering is extremely compelling and was the catalyst for my pursuit of an MS/MBA in Biotechnology degree. As a joint degree student, I benefit from immersive case studies at HBS where my classmates and I are challenged to analyze... View Details

18 Nov 2002
Research & Ideas

Where Morals and Profits Meet: The Corporate Value Shift

information technologies. Recent advances in biotechnology have raised ethical issues that have never before presented themselves. And globalization has given rise to cross-cultural dilemmas that just weren't a major part of the scene in... View Details

Keywords: by Carla Tishler

Profile

Lena Licht

biotechnology despite lacking tangible business experience. I’ll be leaving with the confidence that I can now be a business leader and change maker within my industry, and I cannot wait to hit the ground running after graduation! How... View Details

01 Oct 2021
News

From Scholarship to Life-Saving Impact

focused on patients. “Patients and their families are at the center of why I want to be in the biotechnology space,” she concludes. “When you’re working on rare diseases, it’s hard not to feel like you’re making a difference.” View Details

Web

Student Spotlight: 2023 HCC Co-Presidents Reflect on Their Time at HBS and the Current Health Care Systems - Blog: Health Supplement

decision-making in the life sciences. They complemented the case method with applied learning through projects and written assignments–for example, a mock diligence report for a biotechnology company. Most importantly, the professors were... View Details

17 Sep 2021
Research & Ideas

The Trial of Elizabeth Holmes: Visionary, Criminal, or Both?

Former Theranos employees began testifying this week against Elizabeth Holmes, the once-celebrated biotech’s founder and CEO, in a criminal trial that has Silicon Valley worried. In opening statements last week, federal prosecutors charged that Holmes and the company’s... View Details

Keywords: by Christina Pazzanese, Harvard Gazette; Biotechnology; Biotechnology; Biotechnology

December 2005 (Revised August 2006)
Case

Amgen Inc.'s Epogen--Commercializing the First Biotech Blockbuster Drug

By: Felix Oberholzer-Gee and Dennis A. Yao

Amgen Inc.'s Epogen was the first biotech blockbuster drug. Epogen helped prevent anemia, a condition that leads to severe fatigue, increased risk of cardiovascular disease, and even death. At the time, the market for Epogen, which included dialysis patients and... View Details

Keywords: Health Care and Treatment; Strategic Planning; Competition; Patents; Innovation and Invention; Biotechnology Industry; Biotechnology Industry; United States

Keywords: biotechnology; biotechnology; biotechnology

November 2020
Case

Valuing Celgene's CVR

By: Benjamin C. Esty and Daniel Fisher

When Bristol-Myers Squibb (BMS) acquired Celgene Corporation in November 2019, Celgene shareholders received cash, BMS stock, and a contingent value right (CVRs) that would pay $9 if the U.S. Food and Drug Administration (FDA) approved three of Celgene’s late stage... View Details

Keywords: Mergers and Acquisitions; Value; Valuation; Judgments; Decision Making; Cash Flow; Financial Instruments; Cognition and Thinking; Biotechnology Industry; Biotechnology Industry; United States

12 Jun 2018
Research & Ideas

In a Landscape of 'Me Too' Drug Development, What Spurs Radical Innovation?

portfolios. They examined all companies that held at least one drug patent on the market as of 2003. The researchers focused mainly on small-molecule drugs, not biologics. That’s because of how the compounds are structured chemically. The complicated chemical makeup of... View Details

Keywords: by Rachel Layne; Health; Pharmaceutical

31 Jan 2014
News

Body, Heal Thyself

Chien and Derrick Rossi, published a paper in the journal Nature Biotechnology that showed mRNA Therapeutics was capable of stimulating blood vessel growth, repairing damaged heart tissue, and helping a mouse through myocardial... View Details

Keywords: Maureen Harmon; biotech; Health, Social Assistance; Scientific Research and Development Services

October 2004 (Revised March 2005)
Case

Langer Lab, The: Commercializing Science

By: H. Kent Bowen, Alex Kazaks, Ayr Muir-Harmony and Bryce LaPierre

Professor Robert Langer's laboratory at MIT is the source of an unusually large number of published papers, patents, and technology licenses to start-up and established companies in the biomedical industry. Explores Langer's leadership and other factors that create a... View Details

Keywords: Entrepreneurship; Technological Innovation; Business Startups; Research and Development; Patents; Innovation Leadership; Science-Based Business; Commercialization; Biotechnology Industry; Biotechnology Industry