Publications

May 2011
Article

Nonsimultaneous Chains and Dominos in Kidney Paired Donation—Revisited

By: Itai Ashlagi, Duncan S. Gilchrist, Alvin E. Roth and Michael A. Rees

Since 2008 kidney exchange in America has grown in part from the incorporation of non-directed donors in transplant chains rather than simple exchanges. It is controversial whether these chains should be performed simultaneously ("domino paired donation," DPD) or... View Details

Keywords: ABO Incompatibility; Allosensitization; Paired Kidney Exchange; Regional Sharing; Simulation Models; Transplantation Policy; Health Care and Treatment; Supply Chain; Risk and Uncertainty; Logistics; United States

31 Jan 2012
First Look

First Look: Jan. 31

http://www.hbs.edu/research/pdf/12-063.pdf Team Scaffolds: How Minimal In-Group Structures Support Fast-Paced Teaming Authors:Melissa A. Valentine and Amy C. Edmondson Abstract Across many industries, particularly in health View Details

Keywords: Sean Silverthorne & Carmen Nobel

July 2019
Article

The Impact of Price Regulation on the Availability of New Drugs in Germany

By: Ariel Dora Stern, Felicitas Pietrulla, Annika Herr, Aaron S. Kesselheim and Ameet Sarpatwari

The 2011 German Pharmaceutical Market Restructuring Act (“AMNOG”) subjected branded, non-rare disease drugs to price regulation based on an assessment of their clinical benefit. Assessment outcomes range from “major added benefit” to “less benefit than the appropriate... View Details

Keywords: Regulation; Pharmaceuticals; Healthcare; Health Care and Treatment; Price; Governing Rules, Regulations, and Reforms; Pharmaceutical Industry; Germany

January–February 2021
Article

Food and Drug Administration Guidance Documents and New Medical Devices: The Case of Breast Prostheses

By: Rachel E. Weitzman, Ariel Dora Stern and Daniel B. Kramer

As pressure mounts on the Food and Drug Administration (FDA) to speed its review process for novel devices, and budgetary pressures further strain its resources, the critical role of guidance documents in assuring consistent, rigorous, and scientifically grounded... View Details

Keywords: Medical Devices; FDA; Health Care and Treatment; Government Administration; Information; Standards

October 1998 (Revised April 2000)
Background Note

Complexity and Error in Medicine

By: Richard M.J. Bohmer

Reviews the issues underlying the rate of error in medical practice and discusses the range of potential management interventions to decrease the risk of error. View Details

Keywords: Health Care and Treatment; Management Practices and Processes; Risk and Uncertainty; Complexity

Educators

05 May 2003
Research & Ideas

What It Takes to Restore Trust in Business

far. The American capital markets are a key element of the economic system, and "when they function well, they are a wonder of the world," he said. But the American capital markets require four qualities from those who... View Details

Keywords: by Martha Lagace; Financial Services

11 Jun 2012
Research & Ideas

When Business Competition Harms Society

Competition Corrupts Business Practices, suggests that many organizations in highly competitive markets are likely to bend the rules if doing so will keep their customers from leaving for a rival firm. "Competition is generally thought to be good for economies... View Details

Keywords: by Carmen Nobel; Auto

February 2016
Case

Express Scripts: Promoting Prescription Drug Home Delivery (A)

By: John Beshears, Patrick Rooney and Jenny Sanford

The pharmacy benefit manager (PBM) sector processes prescription drug claims on behalf of companies that offer a prescription drug benefit to their employees. This case follows Bob Nease, Chief Scientist at Express Scripts, as he considers methods to promote home... View Details

Keywords: Pharmaceuticals; Prescription Drugs; Pharmacy Benefit Manager; PBM; Healthcare; Behavioral Economics; Choice Architecture; Active Choice; Service Delivery; Decision Choices and Conditions; Health Care and Treatment; Order Taking and Fulfillment; Compensation and Benefits; Pharmaceutical Industry

Educators

02 Sep 2002
What Do You Think?

What Can Business Schools Do to Avoid Bad Apples?

Summing Up This month's column resulted in a number of suggestions for sorting out the "bad apples" among applicants to MBA programs across the country. But just as many respondents questioned the underlying assumptions of the column. Many respondents... View Details

Keywords: by James Heskett

2023
Working Paper

The Political Economy of a 'Miracle Cure': The Case of Nebulized Ibuprofen and Its Diffusion in Argentina

By: Sebastian Calónico, Rafael Di Tella and Juan Cruz Lopez Del Valle

We document the diffusion of nebulized ibuprofen in Argentina as a treatment for COVID-19. As the pandemic spread, this clinically unsupported drug reached thousands of patients, even some seriously ill, despite warnings by the regulator and medical societies. Detailed... View Details

Keywords: COVID-19; Health Care and Treatment; Health Pandemics; Adoption; Behavior; Governing Rules, Regulations, and Reforms; Learning

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March 2022
Article

Where to Locate COVID-19 Mass Vaccination Facilities?

By: Dimitris Bertsimas, Vassilis Digalakis Jr, Alexander Jacquillat, Michael Lingzhi Li and Alessandro Previero

The outbreak of COVID-19 led to a record-breaking race to develop a vaccine. However, the limited vaccine capacity creates another massive challenge: how to distribute vaccines to mitigate the near-end impact of the pandemic? In the United States in particular, the new... View Details

Keywords: Vaccines; COVID-19; Health Care and Treatment; Health Pandemics; Performance Effectiveness; Analytics and Data Science; Mathematical Methods

29 Jan 2015
Op-Ed

The Fall of Greece

allocated in competitive markets) is far superior to a centrally planned economy where the means of production are controlled by the political process. And the superiority does not come only in terms of economic growth, but also employment, access to View Details

Keywords: by George Serafeim

03 Jul 2012
First Look

First Look: July 3

Klinik: Eating Disorder Care Michael E. Porter, Emma Stanton, Jessica A. Hohman, and Caleb StowellHarvard Business School Case 712-475 The Schön Klinik is a private, for-profit German hospital group trying to establish itself as a premium... View Details

Keywords: Sean Silverthorne

July 2009
Teaching Note

The Miami Project to Cure Paralysis (TN)

By: Robert Steven Kaplan, Christopher Marquis and Ben Creo

Teaching Note for [408003]. View Details

Keywords: Nonprofit Organizations; Research; Health Care and Treatment; Medical Specialties; Financing and Loans; Leadership; Strategy; Problems and Challenges; Health Testing and Trials; Miami

01 Apr 2008
First Look

First Look: April 1, 2008

which, as the former parent of Delphi, has agreed to fund a portion of the massive pension and retiree health care liabilities that Delphi incurred when it separated from GM in a prior spin-off. The company... View Details

Keywords: Martha Lagace

December 5, 2024
Article

A Consensus Definition of Creativity in Surgery: A Delphi Study Protocol

By: Alex Thabane, Tyler McKechnie, Phillip Staibano, Vikram Arora, Goran Calic, Jason W. Busse, Sameer Parpia and Mohit Bhandari

Introduction
Clear definitions are essential in science, particularly in the study of abstract phenomena like creativity. Due to its inherent complexity and domain-specific nature, the study of creativity has been complicated, as evidenced by the various... View Details

Keywords: Creativity; Health Care and Treatment; Outcome or Result; Measurement and Metrics

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May 2023 (Revised June 2023)
Supplement

Novartis (B): Reimagining Medicine

By: Ramon Casadesus-Masanell, Claudio Feser, Karolin Frankenberger and David Redaschi

This case unfolds around the first-ever approved personalized cancer treatment, how Novartis wrapped it into a new business model design, and how Novartis scaled it. Novartis — one of the largest pharmaceutical companies in the world — is, among other ventures,... View Details

Keywords: Health Care and Treatment; Business Model; Production; Business Strategy; Pharmaceutical Industry

Article

Managing the Use and Dissemination of Information about Biomarkers: The Importance of Incentive Structures.

By: Ariel Dora Stern

The use of biomarkers holds great promise for the development of new therapeutics and the acceleration of clinical research. However, biomarkers must be validated—a complex and costly endeavor. Importantly, biomarker validation is meaningfully shaped by economic and... View Details

Keywords: Biomarkers; Information Management; Health Care and Treatment; Motivation and Incentives