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- Faculty Publications (185)
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- 22 Aug 2005
- Research & Ideas
The Hard Work of Failure Analysis
the folly of not adhering strictly to the company's core beliefs.2 Similarly, we have observed failed consulting relationships in our field research in which the consultants simply blamed the failure on the client, concluding that the... View Details
Keywords: by Amy Edmondson & Mark D. Cannon
- 25 Feb 2014
- First Look
First Look: February 25
the weakening of democratic governance and the politics of decisions about industrial policy. Publisher's link: http://www.psupress.org/books/titles/978-0-271-05631-9.html August 2013 Research Policy Digital Dark Matter and the Economic... View Details
Keywords: Sean Silverthorne
- 17 Mar 2009
- First Look
First Look: March 17, 2009
Agreements in Bio-Pharmaceuticals Authors:Juan Alcácer, John Cantwell, and Michelle Gittelman Publication:In Location of Biopharmaceutical Activity, edited by Iain M. Cockburn and Matthew J. Slaughter. NBER, forthcoming. Abstract As the value chain of the View Details
Keywords: Martha Lagace
- 22 Oct 2013
- First Look
First Look: October 22
expenditures on teammates lead to better performance in both sports teams in Canada and pharmaceutical sales teams in Belgium. These results suggest that a minor adjustment to employee bonuses-shifting the focus from the self to... View Details
Keywords: Sean Silverthorne
- 04 May 2010
- First Look
First Look: May 4
Reexamination of Tunneling and Business Groups: New Data and New Methods Authors:Jordan I. Siegel and Prithwiraj Choudhury Abstract The last decade of corporate governance research has been focused in large part on identifying what leads... View Details
Keywords: Martha Lagace
- 15 Jan 2013
- First Look
First Look: January 15
and Use of a New Accounting System Authors:Narayanan, V.G., Ranjani Krishnan, and Jamshed J. Mistry Publication:Journal of Management Accounting Research Abstract This study examines the attitudes, use, and acceptance of a new accounting... View Details
Keywords: Sean Silverthorne
- 12 Nov 2013
- First Look
First Look: November 12
Publications November 2013 Journal of Consumer Research The Red Sneakers Effect: Inferring Status and Competence from Signals of Nonconformity By: Bellezza, Silvia, Francesca Gino, and Anat Keinan Abstract—We examine how people react to... View Details
Keywords: Sean Silverthorne
- 05 May 2015
- First Look
First Look: May 5
causes considerable societal damage, as demonstrated by increasing empirical evidence. Drawing on recent research in moral psychology and behavioral ethics, I examine "moral flexibility," or the common ability to justify one's... View Details
Keywords: Carmen Nobel
- 27 May 2009
- First Look
First Look: May 27, 2009
Case 509-048 The case describes the effort of Merck, a global leader in pharmaceuticals, in making available its medicines to the poor. The challenge for the company (or for that matter, any pharmaceutical company) is how to integrate its... View Details
Keywords: Martha Lagace
- 23 May 2017
- First Look
First Look at New Ideas and Research: May 23, 2017
difficult to understand and implement. We introduce the 4 Minds framework as a practical tool for understanding and applying the science of decision-making in the marketplace. We synthesize previous research on decision-making into four... View Details
Keywords: Carmen Nobel
- 15 Jan 2018
- Research & Ideas
A Better Business Model for Fighting Cancer
iPhoto With billions of dollars spent on the development of precision medicine and related cancer research over the last decade, a recent partnership seeks a new way to bring these treatments to patients more quickly: through a better... View Details
- Research Summary
Overview
By: Andy Wu
How can technology entrepreneurs build competitive advantage from the ground up? Professor Andy Wu conducts scholarly research and develops course materials that document how technology entrepreneurs can (1) organize for innovation to create new market opportunities... View Details
Keywords: Strategy; Entrepreneurship; Venture Capital; Growth Management; Organizational Design; Organizational Structure; Technology Platform; Technological Innovation; Pharmaceutical Industry; Pharmaceutical Industry; Pharmaceutical Industry; Pharmaceutical Industry; Pharmaceutical Industry; United States; China; Southeast Asia; South Asia
- 25 Apr 2005
- Research & Ideas
New Learning at American Home Products
pharmaceutical companies in 1984, American Home Products ranked first in sales and twenty-eighth in R&D expenditures as a percentage of sales.23 As the historian Williams Haynes noted, by the end of the 1930s, American Home Products... View Details
- 10 Sep 2008
- Research & Ideas
Long-Tail Economics? Give Me Blockbusters!
by focusing on bigger films that require a bigger commitment." Jeff Robinov believes in blockbusters and his strategy is to create more of them. The pharmaceutical and entertainment industries are similar. R&D costs in both are... View Details
- 20 Nov 2006
- Research & Ideas
Open Source Science: A New Model for Innovation
scientific problem solving? Yes, and it comes from an unexpected and unrelated corner of the universe: open source software development. That's the view of Karim R. Lakhani, an assistant professor at Harvard Business School with an extensive View Details
Keywords: by Martha Lagace
- June 2006
- Teaching Note
Vertex Pharmaceuticals: R&D Portfolio Management (A), (B), and (C) (TN)
By: Francesca Gino and Gary P. Pisano
- 09 Feb 2018
- Working Paper Summaries
Developing Novel Drugs
- 1999
- Chapter
The Economics of Drug Discovery
By: Rebecca M. Henderson and Iain Cockburn
Henderson, Rebecca M., and Iain Cockburn. "The Economics of Drug Discovery." Chap. 5 in Pharmaceutical Innovation, edited by Ralph Landau, Basil Achilladelis, and Alexander Scriabine, 308–331. Philadelphia: Chemical Heritage Press, 1999.
- September 2024
- Article
Comprehensive Measurement of Biopharmaceutical R&D Investment
By: Amitabh Chandra, John Drum, Michael Daly, Henry Mirsberger, Samuel Spare, Ulrich Neumann, Silas Martin and Noam Kirson
Chandra, Amitabh, John Drum, Michael Daly, Henry Mirsberger, Samuel Spare, Ulrich Neumann, Silas Martin, and Noam Kirson. "Comprehensive Measurement of Biopharmaceutical R&D Investment." Nature Reviews: Drug Discovery 23, no. 9 (September 2024): 652–653.
- 2023
- Working Paper
Evaluation and Learning in R&D Investment
By: Alexander P. Frankel, Joshua L. Krieger, Danielle Li and Dimitris Papanikolaou
We examine the role of spillover learning in shaping the value of exploratory versus incremental
R&D. Using data from drug development, we show that novel drug candidates generate more
knowledge spillovers than incremental ones. Despite being less likely to reach... View Details
Frankel, Alexander P., Joshua L. Krieger, Danielle Li, and Dimitris Papanikolaou. "Evaluation and Learning in R&D Investment." Harvard Business School Working Paper, No. 23-074, May 2023. (NBER Working Paper Series, No. 31290, May 2023.)