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      Technological And Scientific InnovationRemove Technological And Scientific Innovation →

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      • September 2023 (Revised August 2024)
      • Case

      Avive: Resuscitating a Defibrillator from the Regulatory Brink

      By: Satish Tadikonda and William Marks
      Avive Solutions set out to create a better Automatic External Defibrillator (AED) that would solve many of the problems with existing solutions, including lack of connectivity, difficulty-of-use and requiring prior training for successful use of the device, data... View Details
      Keywords: Technological Innovation; Product Development; Business and Government Relations; Research and Development; Medical Devices and Supplies Industry; United States
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      Tadikonda, Satish, and William Marks. "Avive: Resuscitating a Defibrillator from the Regulatory Brink." Harvard Business School Case 824-070, September 2023. (Revised August 2024.)
      • September 2023
      • Background Note

      Amager Bakke: Municipal Waste to Energy

      By: Willy Shih, Michael W. Toffel and Kelsey Carter
      This background note describes the Amager Bakke waste-to-energy (WtE) plant in Copenhagen, which merges traditional waste incineration with a combined heat and power (CHP) plant and air pollution control (scrubbing) technology, and had plans to add carbon dioxide (CO2)... View Details
      Keywords: Decarbonization; Innovation; Innovation Focused Strategy; Environmental Operations; Circular; Waste Heat Recovery; Waste Management; Carbon Regulation; Buildings and Facilities; Energy Generation; Environmental Sustainability; Pollution; Climate Change; Wastes and Waste Processing; Innovation Leadership; Innovation Strategy; Energy Industry; Denmark; Netherlands; Europe; European Union
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      Shih, Willy, Michael W. Toffel, and Kelsey Carter. "Amager Bakke: Municipal Waste to Energy." Harvard Business School Background Note 624-040, September 2023.
      • September 2023
      • Case

      FoodCloud: Tackling Food Insecurity and Climate Change in One Bite

      By: Brian Trelstad and Emer Moloney
      In 2013, Aoibheann O’Brien and Iseult Ward founded FoodCloud, a non-profit social enterprise that aimed to address food waste and food insecurity issues. Through its technology platform, Foodiverse, FoodCloud connected surplus food from retailers with community groups... View Details
      Keywords: Nonprofit Organizations; Expansion; Technological Innovation; Environmental Sustainability; Social Issues; Growth and Development Strategy; Green Technology Industry; Green Technology Industry; Green Technology Industry; Republic of Ireland; Europe
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      Trelstad, Brian, and Emer Moloney. "FoodCloud: Tackling Food Insecurity and Climate Change in One Bite." Harvard Business School Case 324-031, September 2023.
      • September 2023 (Revised January 2024)
      • Case

      AI21 Labs in 2023: Strategy for Generative AI

      By: David Yoffie, Orna Dan and Elena Corsi
      Israeli generative artificial intelligence company AI21 Labs was founded in 2017 to realize the vision of true machine intelligence. It sought to reinvent writing and reading and in 2020 it launched Wordtune, an app using GenAI software to offer alternate text... View Details
      Keywords: Decision Making; AI and Machine Learning; Innovation Strategy; Growth and Development Strategy; Applications and Software; Competitive Strategy; Technology Industry; Israel
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      Yoffie, David, Orna Dan, and Elena Corsi. "AI21 Labs in 2023: Strategy for Generative AI." Harvard Business School Case 724-383, September 2023. (Revised January 2024.)
      • September 2023 (Revised June 2024)
      • Case

      CyberArk: Fearlessly Forward in a Digital World

      By: David B. Yoffie and Daniela Beyersdorfer
      CyberArk was a leader in privileged access management and was an emerging leader in security identity. This case explores strategies in cybersecurity and whether big bets are needed to become a global leader. View Details
      Keywords: Cybersecurity; Strategy; Technological Innovation; Technology Industry
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      Yoffie, David B., and Daniela Beyersdorfer. "CyberArk: Fearlessly Forward in a Digital World." Harvard Business School Case 724-382, September 2023. (Revised June 2024.)
      • September 2023 (Revised July 2024)
      • Case

      Going Mobile-First? The Digital Transformation of Davivienda Bank in Colombia

      By: Jorge Tamayo and Jenyfeer Martinez Buitrago
      Set in 2017, this case describes the digital transformation strategy of Davivienda—a leading player in Colombia’s commercial banking and one of the companies belonging to Grupo Bolívar, a major Colombian financial conglomerate. The case also describes the pioneer role... View Details
      Keywords: Change Management; Transformation; Decision Choices and Conditions; Information Technology; Digital Strategy; Digital Transformation; Internet and the Web; Mobile and Wireless Technology; Innovation and Management; Innovation Strategy; Growth and Development Strategy; Business Strategy; Banking Industry; Latin America; Central America; South America; Colombia
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      Tamayo, Jorge, and Jenyfeer Martinez Buitrago. "Going Mobile-First? The Digital Transformation of Davivienda Bank in Colombia." Harvard Business School Case 724-389, September 2023. (Revised July 2024.)
      • September 2023 (Revised April 2024)
      • Case

      Atomwise: Strategic Opportunities in AI for Pharma

      By: Satish Tadikonda
      Abraham Heifets and his co-founder, Izhar Wallach, had founded Atomwise to develop i) an AI engine to transform drug discovery by creating better medicines faster, and ii) a machine learning-based discovery engine that combined the power of convolutional neural... View Details
      Keywords: Business Model; Business Startups; AI and Machine Learning; Science-Based Business; Technological Innovation; Biotechnology Industry; Pharmaceutical Industry
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      Tadikonda, Satish. "Atomwise: Strategic Opportunities in AI for Pharma." Harvard Business School Case 824-043, September 2023. (Revised April 2024.)
      • September 2023
      • Teaching Note

      Apple’s iPhone Revolution: Pioneering the Circular Economy

      By: George Serafeim
      Teaching Note for HBS Case 123-089. The case describes the Trade-In system for iPhones that allow iPhones to be refurbished and reused or to be recycled. The case provides information for the students to analyze the financial attractiveness of the Trade-In system and... View Details
      Keywords: Iphone; Smartphone; Technology; Business Model Innovation; Carbon Emissions; Recycling; Business Model; Product Design; Climate Change; Environmental Sustainability; Green Technology; Technology Industry
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      Serafeim, George. "Apple’s iPhone Revolution: Pioneering the Circular Economy." Harvard Business School Teaching Note 124-026, September 2023.
      • September 2023 (Revised January 2024)
      • Case

      RightHand Robotics: Choosing the First Market

      By: Thomas R. Eisenmann and Stacy Straaberg
      In early 2015, RightHand Robotics’s (RHR) leadership faced a set of decisions in commercializing the startup’s robotic picking solution. RHR’s central product was the RightPick integrated robotic picking system which featured a robotic arm, a three-fingered robotic... View Details
      Keywords: Business Startups; Market Entry and Exit; Product; Research and Development; Business Strategy; Commercialization; Information Infrastructure; Technological Innovation; Technology Industry; Technology Industry; United States; Massachusetts
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      Eisenmann, Thomas R., and Stacy Straaberg. "RightHand Robotics: Choosing the First Market." Harvard Business School Case 824-006, September 2023. (Revised January 2024.)
      • September 2023 (Revised March 2024)
      • Case

      ReMo Energy: Sizing Up Investors

      By: Jeffrey J. Bussgang and Tom Quinn
      In 2023, executives with ReMo Energy (founded 2020) were deciding which size ammonia plant to build as their first project. Their innovative model produced ammonia—useful for making fertilizer and for energy storage—from renewable energy, and they had received funding... View Details
      Keywords: Factories, Labs, and Plants; Business Startups; Cost vs Benefits; Design; Energy Conservation; Energy Generation; Renewable Energy; Venture Capital; Investment Return; Goods and Commodities; Size; Infrastructure; Risk and Uncertainty; Science-Based Business; Commercialization; Technological Innovation; Green Technology Industry; Green Technology Industry; Green Technology Industry; United States; Boston
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      Bussgang, Jeffrey J., and Tom Quinn. "ReMo Energy: Sizing Up Investors." Harvard Business School Case 824-027, September 2023. (Revised March 2024.)
      • 2025
      • Working Paper

      Better Keep the Twenty Dollars: Incentivizing Innovation in Open Source

      By: Annamaria Conti, Vansh Gupta, Jorge Guzman and Maria P. Roche
      Open source is key to innovation yet is assumed to be done largely through intrinsic motivation. How can we incentivize it? In this paper, we examine the impact of a program providing monetary incentives to motivate innovators to contribute to open source. The Sponsors... View Details
      Keywords: Open Source; Innovation; Incentives; Financial Rewards; Crowding Out; Open Source Distribution; Innovation and Invention; Motivation and Incentives; Technology Industry
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      Conti, Annamaria, Vansh Gupta, Jorge Guzman, and Maria P. Roche. "Better Keep the Twenty Dollars: Incentivizing Innovation in Open Source." Harvard Business School Working Paper, No. 24-014, September 2023. (Revised January 2025. NBER Working Paper Series, No. 31668, September 2023)
      • September 2023
      • Case

      Diamond Standard

      By: Lauren H. Cohen, Zhaoheng Gong and Grace Headinger
      Cormac Kinney, Founder and CEO of Diamond Standard, was on a mission to transform the U.S. diamond market through unlocking the precious gems as market-traded assets. As a serial FinTech entrepreneur, he hoped to add an additional service to his vault: Carats. The... View Details
      Keywords: Tokenization; Fintech; Cryptocurrency; Liquidity; Digital; Rare Earth Minerals; Decentralized; Crypto Economy; Financial Product; Metals; Diamonds; Commodity; Assets; Financial Instruments; Financial Institutions; Financial Markets; Investment; Technological Innovation; Natural Resources; Business Startups; Currency; Financial Services Industry; United States
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      Cohen, Lauren H., Zhaoheng Gong, and Grace Headinger. "Diamond Standard." Harvard Business School Case 224-009, September 2023.
      • September 2023 (Revised May 2025)
      • Teaching Note

      On (A) and (B)

      By: Ramon Casadesus-Masanell, Karolin Frankenberger, Sascha Mader, Jordan Mitchell and Karen Elterman
      Teaching Note for "On," HBS Case No. 723-430. On is a premium performance running shoe company founded in Switzerland in 2010. The company rapidly gained traction through its unique CloudTec cushioning technology, its innovative midsole plate called the Speedboard, and... View Details
      Keywords: Brands and Branding; Business Growth and Maturation; Business Model; Business Startups; Business Strategy; Competitive Advantage; Competitive Strategy; Corporate Strategy; Customer Focus and Relationships; Customer Satisfaction; Digital Marketing; Disruptive Innovation; Distribution Channels; Entrepreneurship; Environmental Sustainability; Global Strategy; Initial Public Offering; Innovation and Invention; Innovation Strategy; Market Entry and Exit; Marketing Strategy; Product Design; Product Development; Product Marketing; Social Media; Strategy; Supply Chain Management; Technological Innovation; Apparel and Accessories Industry; Apparel and Accessories Industry; Apparel and Accessories Industry; Apparel and Accessories Industry; Apparel and Accessories Industry; Europe; Germany; Switzerland; United States
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      Casadesus-Masanell, Ramon, Karolin Frankenberger, Sascha Mader, Jordan Mitchell, and Karen Elterman. "On (A) and (B)." Harvard Business School Teaching Note 724-375, September 2023. (Revised May 2025.)
      • September 2023 (Revised September 2023)
      • Supplement

      On Slides

      By: Ramon Casadesus-Masanell, Karolin Frankenberger, Sascha Mader, Jordan Mitchell and Karen Elterman
      Slides to support the teaching of the On case, 723-430. On is a premium performance running shoe company founded in Switzerland in 2010. The company rapidly gained traction through its unique CloudTec cushioning technology, its innovative midsole plate called the... View Details
      Keywords: Brands and Branding; Business Growth and Maturation; Business Model; Business Startups; Business Strategy; Competitive Advantage; Competitive Strategy; Corporate Strategy; Customer Focus and Relationships; Customer Satisfaction; Digital Marketing; Disruptive Innovation; Distribution Channels; Entrepreneurship; Environmental Sustainability; Global Strategy; Initial Public Offering; Innovation and Invention; Innovation Strategy; Market Entry and Exit; Marketing Strategy; Product Design; Product Development; Product Marketing; Social Media; Strategy; Supply Chain Management; Technological Innovation; Apparel and Accessories Industry; Apparel and Accessories Industry; Apparel and Accessories Industry; Apparel and Accessories Industry; Apparel and Accessories Industry; Europe; Germany; Switzerland; United States
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      Casadesus-Masanell, Ramon, Karolin Frankenberger, Sascha Mader, Jordan Mitchell, and Karen Elterman. "On Slides." Harvard Business School PowerPoint Supplement 724-376, September 2023. (Revised September 2023.)
      • August 2023 (Revised December 2023)
      • Case

      Automating Morality: Ethics for Intelligent Machines

      By: Joseph L. Badaracco Jr. and Tom Quinn
      As autonomy became a more significant part of modern life – most notably in autonomous vehicles (AVs), such as Teslas – ethical debates about whether and how to impart ethics to machines heated up. Utilitarians pointed out that autonomous vehicles crashed much less... View Details
      Keywords: Cost vs Benefits; Judgments; Fairness; Moral Sensibility; Values and Beliefs; Cross-Cultural and Cross-Border Issues; Disruptive Innovation; Technology Adoption; Risk and Uncertainty; Cognition and Thinking; Technological Innovation; Technology Industry; Technology Industry; Africa; Asia; Europe; North and Central America; Oceania; South America
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      Badaracco, Joseph L., Jr., and Tom Quinn. "Automating Morality: Ethics for Intelligent Machines." Harvard Business School Case 324-007, August 2023. (Revised December 2023.)
      • August 2023
      • Case

      Beamery: Using Skills and AI to Modernize HR

      By: Boris Groysberg, Alexis Lefort, Susan Pinckney and Carolina Bartunek
      Unicorn human relationships startup Beamery evaluates it's growth versus depth strategy as its strategic partners and customers could become future competitors in a quickly changing AI based human resources and talent management industry View Details
      Keywords: Acquisition; Business Growth and Maturation; Business Startups; Competency and Skills; Experience and Expertise; Talent and Talent Management; Customers; Nationality; Learning; Entrepreneurship; Employee Relationship Management; Recruitment; Retention; Selection and Staffing; Values and Beliefs; Cross-Cultural and Cross-Border Issues; Analytics and Data Science; Applications and Software; Disruptive Innovation; Technological Innovation; Job Offer; Job Search; Job Design and Levels; Employment; Human Capital; Europe; United Kingdom; United States
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      Groysberg, Boris, Alexis Lefort, Susan Pinckney, and Carolina Bartunek. "Beamery: Using Skills and AI to Modernize HR." Harvard Business School Case 424-004, August 2023.
      • August 2023
      • Case

      Augmenix: Space to Think Differently

      By: Satish Tadikonda and Sidhant Jena
      Amar Sawhney, a serial medtech entrepreneur, had founded Augmenix to develop and commercialize a hydrogel-based medical device called SpaceOAR as an adjunctive technology to core radiation therapy. This technology was used to protect organs at risk (OAR) during... View Details
      Keywords: Entrepreneurship; Health Care and Treatment; Technology Adoption; Innovation Strategy; Technological Innovation; Product Development; Commercialization; Medical Devices and Supplies Industry
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      Tadikonda, Satish, and Sidhant Jena. "Augmenix: Space to Think Differently." Harvard Business School Case 824-031, August 2023.
      • August 2023
      • Case

      Kariyer.net: Recruiting AI

      By: Shunyuan Zhang, Fares Khrais and Namrata Arora
      In 2017, Fatih Uysal (AMP 2021) became CEO of Kariyer.net. By then, the business was already the industry leading online job board in Turkey. However, faced with stalling growth, a turbulent macroenvironment, and growing competition from international players, Uysal... View Details
      Keywords: Online Technology; Marketing; Websites; Artificial Intelligence; Innovation; Two-sided Platforms; Internet and the Web; Product Launch; Product Positioning; Job Search; Employment; Transformation; Volatility; Innovation and Invention; Disruptive Innovation; Management Practices and Processes; Business Growth and Maturation; Competitive Strategy; Business Startups; Talent and Talent Management; Cost vs Benefits; Macroeconomics; Corporate Entrepreneurship; Emerging Markets; Digital Platforms; Information Technology Industry; Information Technology Industry; Information Technology Industry; Middle East; Turkey
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      Zhang, Shunyuan, Fares Khrais, and Namrata Arora. "Kariyer.net: Recruiting AI." Harvard Business School Case 524-014, August 2023.
      • 2024
      • Working Paper

      The Crowdless Future? Generative AI and Creative Problem Solving

      By: Léonard Boussioux, Jacqueline N. Lane, Miaomiao Zhang, Vladimir Jacimovic and Karim R. Lakhani
      The rapid advances in generative artificial intelligence (AI) open up attractive opportunities for creative problem-solving through human-guided AI partnerships. To explore this potential, we initiated a crowdsourcing challenge focused on sustainable, circular economy... View Details
      Keywords: Large Language Models; Crowdsourcing; Generative Ai; Creative Problem-solving; Organizational Search; AI-in-the-loop; Prompt Engineering; AI and Machine Learning; Innovation and Invention
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      Boussioux, Léonard, Jacqueline N. Lane, Miaomiao Zhang, Vladimir Jacimovic, and Karim R. Lakhani. "The Crowdless Future? Generative AI and Creative Problem Solving." Harvard Business School Working Paper, No. 24-005, July 2023. (Revised July 2024.)
      • August 2023
      • Article

      Explaining Machine Learning Models with Interactive Natural Language Conversations Using TalkToModel

      By: Dylan Slack, Satyapriya Krishna, Himabindu Lakkaraju and Sameer Singh
      Practitioners increasingly use machine learning (ML) models, yet models have become more complex and harder to understand. To understand complex models, researchers have proposed techniques to explain model predictions. However, practitioners struggle to use... View Details
      Keywords: AI and Machine Learning; Technological Innovation; Technology Adoption
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      Slack, Dylan, Satyapriya Krishna, Himabindu Lakkaraju, and Sameer Singh. "Explaining Machine Learning Models with Interactive Natural Language Conversations Using TalkToModel." Nature Machine Intelligence 5, no. 8 (August 2023): 873–883.
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