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      • September 2023 (Revised August 2024)
      • Case

      Avive: Resuscitating a Defibrillator from the Regulatory Brink

      By: Satish Tadikonda and William Marks
      Avive Solutions set out to create a better Automatic External Defibrillator (AED) that would solve many of the problems with existing solutions, including lack of connectivity, difficulty-of-use and requiring prior training for successful use of the device, data... View Details
      Keywords: Technological Innovation; Product Development; Business and Government Relations; Research and Development; Medical Devices and Supplies Industry; United States
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      Tadikonda, Satish, and William Marks. "Avive: Resuscitating a Defibrillator from the Regulatory Brink." Harvard Business School Case 824-070, September 2023. (Revised August 2024.)
      • September 2023 (Revised September 2023)
      • Teaching Note

      Roche: Innovation and Access to Healthcare

      By: George Serafeim
      Teaching Note for HBS Case No. 123-075. In May 2022, Roche Group, one of the largest healthcare companies in the world, hosted its first investor event focused exclusively on its efforts to impact access to healthcare. While Roche had recently set an ambitious goal to... View Details
      Keywords: ESG; Access To Care; Healthcare; Healthcare Access; Innovation; Social Impact; Affordable; Health Care and Treatment; Innovation and Invention; Product Development; Resource Allocation; Corporate Social Responsibility and Impact; Health Industry
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      Serafeim, George. "Roche: Innovation and Access to Healthcare." Harvard Business School Teaching Note 124-028, September 2023. (Revised September 2023.)
      • September 2023 (Revised January 2024)
      • Case

      Icahn Enterprises: Ponzi Scheme or Sound Investment

      By: Aiyesha Dey, Jonas Heese and James Weber
      Icahn Enterprises, a publicly traded limited partnership founded and operated by famed activist investor Carl Icahn, had earned above market returns for over a decade. Between 2018 and early 2023, it had a compound annual return of 31%. Icahn invested in undervalued... View Details
      Keywords: Stock Shares; Investment Return; Business Model; Valuation; Financial Services Industry
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      Dey, Aiyesha, Jonas Heese, and James Weber. "Icahn Enterprises: Ponzi Scheme or Sound Investment." Harvard Business School Case 124-013, September 2023. (Revised January 2024.)
      • September 2023 (Revised December 2023)
      • Case

      TetraScience: Noise and Signal

      By: Thomas R. Eisenmann and Tom Quinn
      In 2019, TetraScience CEO “Spin” Wang needed advice. Five years earlier, he had cofounded a startup that saw early success with a hardware product designed to help laboratory scientists in the biotechnology and pharmaceutical spaces more easily collect data from... View Details
      Keywords: Entrepreneurship; Business Growth and Maturation; Business Organization; Restructuring; Forecasting and Prediction; Digital Platforms; Analytics and Data Science; AI and Machine Learning; Organizational Structure; Network Effects; Competitive Strategy; Biotechnology Industry; Pharmaceutical Industry; United States; Boston
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      Eisenmann, Thomas R., and Tom Quinn. "TetraScience: Noise and Signal." Harvard Business School Case 824-024, September 2023. (Revised December 2023.)
      • September 2023 (Revised July 2024)
      • Case

      Going Mobile-First? The Digital Transformation of Davivienda Bank in Colombia

      By: Jorge Tamayo and Jenyfeer Martinez Buitrago
      Set in 2017, this case describes the digital transformation strategy of Davivienda—a leading player in Colombia’s commercial banking and one of the companies belonging to Grupo Bolívar, a major Colombian financial conglomerate. The case also describes the pioneer role... View Details
      Keywords: Change Management; Transformation; Decision Choices and Conditions; Information Technology; Digital Strategy; Digital Transformation; Internet and the Web; Mobile and Wireless Technology; Innovation and Management; Innovation Strategy; Growth and Development Strategy; Business Strategy; Banking Industry; Latin America; Central America; South America; Colombia
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      Tamayo, Jorge, and Jenyfeer Martinez Buitrago. "Going Mobile-First? The Digital Transformation of Davivienda Bank in Colombia." Harvard Business School Case 724-389, September 2023. (Revised July 2024.)
      • September 2023 (Revised April 2024)
      • Case

      Atomwise: Strategic Opportunities in AI for Pharma

      By: Satish Tadikonda
      Abraham Heifets and his co-founder, Izhar Wallach, had founded Atomwise to develop i) an AI engine to transform drug discovery by creating better medicines faster, and ii) a machine learning-based discovery engine that combined the power of convolutional neural... View Details
      Keywords: Business Model; Business Startups; AI and Machine Learning; Science-Based Business; Technological Innovation; Biotechnology Industry; Pharmaceutical Industry
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      Tadikonda, Satish. "Atomwise: Strategic Opportunities in AI for Pharma." Harvard Business School Case 824-043, September 2023. (Revised April 2024.)
      • Summer 2023
      • Article

      (Un)principled Agents: Monitoring Loyalty after the End of the Royal African Company Monopoly

      By: Anne Ruderman and Marlous van Waijenburg
      The revocation of the Royal African Company's monopoly in 1698 inaugurated a transformation of the transatlantic slave trade. While the RAC’s exit from the slave trade has received scholarly attention, little is known about the company’s response to the loss of its... View Details
      Keywords: Slavery; Organizational Change and Adaptation; Business History; Monopoly; History; Business and Government Relations
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      Ruderman, Anne, and Marlous van Waijenburg. "(Un)principled Agents: Monitoring Loyalty after the End of the Royal African Company Monopoly." Special Issue on Business, Capitalism, and Slavery edited by Marlous van Waijenburg and Anne Ruderman. Business History Review 97, no. 2 (Summer 2023): 247–281.
      • September–October 2023
      • Article

      The New Era of Industrial Policy Is Here

      By: Willy C. Shih
      Governments around the world are increasingly intervening in the private sector through industrial policies designed to help domestic sectors reach goals that markets alone are unlikely to achieve. Companies in targeted sectors—such as automakers, energy companies, and... View Details
      Keywords: Policy; Government and Politics; Business and Government Relations; Research and Development; Economic Sectors
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      Shih, Willy C. "The New Era of Industrial Policy Is Here." Harvard Business Review 101, no. 5 (September–October 2023): 66–75.
      • August 2023
      • Case

      Constellation Pharmaceuticals: Corporate Development at a Novel Therapeutic Company

      By: Satish Tadikonda and Brad Prosek
      Constellation Pharmaceuticals was a company focused on epigenetic therapies for cancer patients. Despite a promising start and an early deal with a leading biopharma company, the company weathered twin setbacks in the end of a major research collaboration and the... View Details
      Keywords: Mergers and Acquisitions; Health Care and Treatment; Organizational Change and Adaptation; Research and Development; Business Strategy; Partners and Partnerships; Goals and Objectives; Pharmaceutical Industry; United States
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      Tadikonda, Satish, and Brad Prosek. "Constellation Pharmaceuticals: Corporate Development at a Novel Therapeutic Company." Harvard Business School Case 824-032, August 2023.
      • 2023
      • Working Paper

      LALIGA—From a Soccer Competition Organizer to a Global Player in the Sports and Entertainment Industry

      By: Stephen A. Greyser, Kenneth Cortsen and Juan Fuentes Fernández
      LALIGA, the first- and second-tier professional soccer league (known as “football” outside of the U.S. and Canada) in Spain, enters its 100th soccer season later this decade. The most popular game in the world (Giulianotti, 2012) has gone through many changes since... View Details
      Keywords: Soccer; "Sports Organizations,; Business History; Strategy; Brands and Branding; Technology Adoption; Sports Industry
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      Greyser, Stephen A., Kenneth Cortsen, and Juan Fuentes Fernández. "LALIGA—From a Soccer Competition Organizer to a Global Player in the Sports and Entertainment Industry." Harvard Business School Working Paper, No. 24-009, August 2023.
      • August 2023
      • Case

      Quotient

      By: Thomas R. Eisenmann and Matt Higgins
      The founders of Quotient, a web-based service for onboarding new engineers, face decisions about how to bring their nascent product to market amidst a tech sector contraction. View Details
      Keywords: Engineers; Entrepreneurial Management; Growth; Go-to-market; Product Management; Entrepreneurship; Business Startups; Product Launch; Market Entry and Exit; Strategy; New York (city, NY); San Francisco
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      Eisenmann, Thomas R., and Matt Higgins. "Quotient." Harvard Business School Case 824-048, August 2023.
      • August 2023
      • Case

      Kariyer.net: Recruiting AI

      By: Shunyuan Zhang, Fares Khrais and Namrata Arora
      In 2017, Fatih Uysal (AMP 2021) became CEO of Kariyer.net. By then, the business was already the industry leading online job board in Turkey. However, faced with stalling growth, a turbulent macroenvironment, and growing competition from international players, Uysal... View Details
      Keywords: Online Technology; Marketing; Websites; Artificial Intelligence; Innovation; Two-sided Platforms; Internet and the Web; Product Launch; Product Positioning; Job Search; Employment; Transformation; Volatility; Innovation and Invention; Disruptive Innovation; Management Practices and Processes; Business Growth and Maturation; Competitive Strategy; Business Startups; Talent and Talent Management; Cost vs Benefits; Macroeconomics; Corporate Entrepreneurship; Emerging Markets; Digital Platforms; Employment Industry; Information Technology Industry; Technology Industry; Middle East; Turkey
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      Zhang, Shunyuan, Fares Khrais, and Namrata Arora. "Kariyer.net: Recruiting AI." Harvard Business School Case 524-014, August 2023.
      • 2023
      • Working Paper

      Corporate Leaders Say They Are for Stakeholder Capitalism—But Which Version Exactly?: A Critical Look at Four Varieties

      By: Lynn S. Paine
      The past few years have seen an outpouring of articles and statements heralding the arrival of a new and more inclusive form of capitalism often called stakeholder capitalism. The new capitalism promises to strengthen companies, improve outcomes for their... View Details
      Keywords: Stakeholder Capitalism; Corporate Governance; Governing and Advisory Boards; Business and Stakeholder Relations; Economic Systems; Business and Shareholder Relations
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      Paine, Lynn S. "Corporate Leaders Say They Are for Stakeholder Capitalism—But Which Version Exactly? A Critical Look at Four Varieties." Harvard Business School Working Paper, No. 24-008, August 2023.
      • 2023
      • Book

      Precarious Ties: Business and the State in Authoritarian Asia

      By: Meg Rithmire
      Developing Asia has been the site of some of the last century's fastest growing economies as well as some of the world's most durable authoritarian regimes. Many accounts of rapid growth alongside monopolies on political power have focused on crony relationships... View Details
      Keywords: Business and Government Relations; Developing Countries and Economies; Economic Systems; Crime and Corruption; China; Indonesia; Malaysia
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      Rithmire, Meg. Precarious Ties: Business and the State in Authoritarian Asia. Oxford University Press, 2023.
      • August 2023 (Revised August 2023)
      • Case

      Sky Therapeutics: Innovating in Digital Therapeutics

      By: Satish Tadikonda, Olivia Reszczynski and William Marks
      Shad Faraz and Alex Youssef were intrigued by the opportunities in the relatively new area of Digital Therapeutics. Despite initial successes, early entrants had struggled with reimbursement and revenue-predictability challenges. However, venture investors still... View Details
      Keywords: Business Startups; Entrepreneurship; Mission and Purpose; Health Industry; Technology Industry
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      Tadikonda, Satish, Olivia Reszczynski, and William Marks. "Sky Therapeutics: Innovating in Digital Therapeutics." Harvard Business School Case 824-023, August 2023. (Revised August 2023.)
      • 2025
      • Working Paper

      When Where Watt: Harnessing the Value of Time and Location for Renewable Electricity Generation

      By: Vishrut Rana, Christian Kaps and Serguei Netessine
      Problem definition: Investments in renewable energy have surged worldwide in recent years, with over $2 trillion spent globally on clean energy. This surge was driven by growing policy support, concerns about energy security, and, most importantly, the cost... View Details
      Keywords: Wind Power; Electricity Distribution; Renewable Energy; Profit; Investment Return; Factories, Labs, and Plants; Geographic Location; Revenue; Energy Industry; Utilities Industry
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      Rana, Vishrut, Christian Kaps, and Serguei Netessine. "When Where Watt: Harnessing the Value of Time and Location for Renewable Electricity Generation." Working Paper, January 2025.
      • July 2023
      • Case

      Honeycomb

      By: Jeffrey J. Bussgang and Kumba Sennaar
      Honeycomb, an audio app enabling seniors to record stories and save family memories, suddenly draws interest from a younger user demographic. The co-founders consider pivoting to better serve this new user demographic. How should they think about strategy, brand, and... View Details
      Keywords: Entrepreneurship; Venture Capital; Operations; Business Startups; Customer Focus and Relationships; Age; Brands and Branding; Technology Industry; United States
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      Bussgang, Jeffrey J., and Kumba Sennaar. "Honeycomb." Harvard Business School Case 824-012, July 2023.
      • July 2023
      • Supplement

      Honeycomb (B): Jumping on The Generative AI Bandwagon?

      By: Jeffrey J. Bussgang and Kumba Sennaar
      Honeycomb, an audio app enabling users to record stories and save family memories, considers pivoting to embrace generative AI. What should the co-founders business model look like if they pursued this new direction? View Details
      Keywords: Entrepreneurship; Venture Capital; Operations; Business Startups; Business Model; AI and Machine Learning; Technology Industry; United States
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      Bussgang, Jeffrey J., and Kumba Sennaar. "Honeycomb (B): Jumping on The Generative AI Bandwagon?" Harvard Business School Supplement 824-013, July 2023.
      • 18 Jul 2023
      • Interview

      Jeffrey Rayport on Product Market Fit, Profit Market Fit and Whiplash, and More

      By: Jeffrey F. Rayport and Doug Levin
      This episode of "Lessons from Startup Life" podcast features Jeffrey Rayport, Senior Lecturer of Business Administration at the Harvard Business School. Jeffrey specializes in teaching and researching growth-stage technology ventures and their scalability. Prior to... View Details
      Keywords: Scaling And Growth; Start-up; Diversity; Equity; Inclusion; Technology; Business Startups; Product Marketing; Business Growth and Maturation
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      "Jeffrey Rayport on Product Market Fit, Profit Market Fit and Whiplash, and More." Lessons from a Startup Life (podcast), July 18, 2023.
      • July 2023 (Revised February 2024)
      • Case

      Equity Restructuring at Dell Technologies: Buy Out, Buy Up, Buy In (A)

      By: Stuart C. Gilson and Sarah L. Abbott
      In November 2018, Dell Technologies was poised to re-enter the public markets by means of a complex recapitalization that would replace an entire class of publicly-traded “tracking stock,” with new shares that would trade publicly without the need of a formal IPO. The... View Details
      Keywords: Technology; M&A; Recapitalization; MBO; Equity Issues; Private Equity Buyouts; Public Ownership; Stock Shares; Mergers and Acquisitions; Equity; Technology Industry; United States
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      Gilson, Stuart C., and Sarah L. Abbott. "Equity Restructuring at Dell Technologies: Buy Out, Buy Up, Buy In (A)." Harvard Business School Case 224-005, July 2023. (Revised February 2024.)
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