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    • All HBS Web  (1,020)
      • Faculty Publications  (263)

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      • Article

      Scale and Scope in Drug Development: Unpacking the Advantages of Size in Pharmaceutical Research

      By: Rebecca Henderson and Iain Cockburn
      Keywords: Research and Development; Health; Size
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      Henderson, Rebecca, and Iain Cockburn. "Scale and Scope in Drug Development: Unpacking the Advantages of Size in Pharmaceutical Research." Journal of Health Economics 20, no. 6 (November 2001).
      • December 2000
      • Case

      Drug Wars, The: Pfizer's Hostile Bid for Warner-Lambert in 1999

      By: Stephen P. Bradley and Matthew Sandoval
      Describes Pfizer's hostile bid for Warner-Lambert in the fall of 1999. Allows for an evaluation of the possible synergies created and poses the question as to whether Pfizer will pay too much. View Details
      Keywords: Acquisition; Bids and Bidding; Competitive Strategy; Valuation
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      Bradley, Stephen P., and Matthew Sandoval. "Drug Wars, The: Pfizer's Hostile Bid for Warner-Lambert in 1999." Harvard Business School Case 701-009, December 2000.
      • October 2000 (Revised March 2003)
      • Case

      Merck & Company: Evaluating a Drug Licensing Opportunity

      By: Richard S. Ruback and David B Krieger
      This explores the valuation of an opportunity to license a compound before it enters clinical trials. Describes Merck's decision tree evaluation process is presented. Information required to evaluate a specific licensing opportunity is provided, including the costs of... View Details
      Keywords: Decision Making; Cost vs Benefits; Opportunities; Valuation; Outcome or Result; Pharmaceutical Industry
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      Ruback, Richard S., and David B Krieger. "Merck & Company: Evaluating a Drug Licensing Opportunity." Harvard Business School Case 201-023, October 2000. (Revised March 2003.)
      • 2000
      • Chapter

      Measuring Competence? Exploring Firm Effects in Drug Discovery

      By: Rebecca M. Henderson and Iain Cockburn
      Keywords: Competency and Skills; Measurement and Metrics; Research and Development; Innovation and Invention; Pharmaceutical Industry
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      Henderson, Rebecca M., and Iain Cockburn. "Measuring Competence? Exploring Firm Effects in Drug Discovery." Chap. 6 in The Nature and Dynamics of Organizational Capabilities, edited by Giovanni Dosi, Richard Nelson, and Sidney Winter. New York: Oxford University Press, 2000.
      • Article

      Strategic Assets, Interdependence and Technological Change: An Empirical Investigation of Complementarity in Pharmaceutical Drug Discovery

      By: S. Thomke and W. Kuemmerle
      Keywords: Strategy; Assets; Information Technology; Change; Information; Health; Pharmaceutical Industry
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      Thomke, S., and W. Kuemmerle. "Strategic Assets, Interdependence and Technological Change: An Empirical Investigation of Complementarity in Pharmaceutical Drug Discovery." Academy of Management Proceedings and Membership Directory (2000).
      • July – August 2000
      • Article

      Drug Industry Mergers Won't Necessarily Benefit R&D

      By: Rebecca M. Henderson
      Keywords: Mergers and Acquisitions; Health; Research and Development
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      Henderson, Rebecca M. "Drug Industry Mergers Won't Necessarily Benefit R&D." Research-Technology Management 43, no. 4 (July–August 2000): 10–11.
      • 1996
      • Chapter

      Eli Lilly and Company: Drug Development Strategy

      By: S. Thomke, A. Nimgade and P. Pospisil
      Keywords: Product Development; Corporate Strategy; Pharmaceutical Industry
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      Thomke, S., A. Nimgade, and P. Pospisil. "Eli Lilly and Company: Drug Development Strategy." In Strategic Management of Technology and Innovation. 2nd ed. by R. Burgelman, M. A. Maidique, and S. C. Wheelwright. Burr Ridge, IL: Irwin/McGraw-Hill, 1996.
      • 1996
      • Chapter

      Note on New Drug Development in the United States

      By: S. Thomke and A. Nimgade
      Keywords: Product Development; Pharmaceutical Industry; United States
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      Thomke, S., and A. Nimgade. "Note on New Drug Development in the United States." In Strategic Management of Technology and Innovation. 2nd ed. by R. Burgelman, M. A. Maidique, and S. C. Wheelwright. Burr Ridge, IL: Irwin/McGraw-Hill, 1996.
      • February 2000 (Revised October 2000)
      • Case

      Kendle International Inc.

      By: Dwight B. Crane, Paul W. Marshall and Indra Reinbergs
      Candace Kendle and Christopher Bergen, the CEO and COO of Kendle International, Inc., are reviewing ways to finance the growth of their privately-owned company. Kendle is a contract research organization that conducts clinical drug trials for pharmaceutical and... View Details
      Keywords: Acquisition; Financing and Loans; Venture Capital; Stock Options; Banks and Banking; Debt Securities; International Finance; Financial Strategy; Management Skills; Private Ownership; Initial Public Offering; Biotechnology Industry; Pharmaceutical Industry
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      Crane, Dwight B., Paul W. Marshall, and Indra Reinbergs. "Kendle International Inc." Harvard Business School Case 200-033, February 2000. (Revised October 2000.)
      • Article

      Incidence and Preventability of Adverse Drug Events in the Nursing Home Setting

      By: J. H. Gurwitz, T. S. Field, J. Avorn, D. McCormick, S. Jain, M. Eckler, M. Benser, A. Edmondson and D. W. Bates
      Keywords: Health; Health Industry
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      Gurwitz, J. H., T. S. Field, J. Avorn, D. McCormick, S. Jain, M. Eckler, M. Benser, A. Edmondson, and D. W. Bates. "Incidence and Preventability of Adverse Drug Events in the Nursing Home Setting." American Journal of Medicine 109, no. 2 (2000): 87–94.
      • December 1999 (Revised August 2001)
      • Case

      Millennium Pharmaceuticals, Inc. (A)

      By: Stefan H. Thomke and Ashok Nimgade
      Focuses on Millennium's strategy to grow and revolutionize drug development through the use of new technologies such as genomics. Describes how Millennium Pharmaceuticals--a fast-growing biotechnology firm in Cambridge, MA--has used strategic alliances to finance the... View Details
      Keywords: Cost Management; Financing and Loans; Medical Specialties; Retention; Growth and Development Strategy; Time Management; Product Development; Problems and Challenges; Alliances; Technology; Biotechnology Industry; Pharmaceutical Industry; Cambridge
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      Thomke, Stefan H., and Ashok Nimgade. "Millennium Pharmaceuticals, Inc. (A)." Harvard Business School Case 600-038, December 1999. (Revised August 2001.)
      • December 1999 (Revised February 2001)
      • Case

      CVS: The Web Strategy

      By: John A. Deighton and Anjali C. Shah
      How should America's second-largest pharmacy chain respond to the challenge from online drugstores? What threat does the web pose to bricks and mortar distribution of prescription drugs and the other items that make up 50% of a drugstore's sales? This case describes... View Details
      Keywords: Leveraged Buyouts; Marketing Channels; Distribution Channels; Service Operations; Corporate Strategy; Pharmaceutical Industry; Web Services Industry
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      Deighton, John A., and Anjali C. Shah. "CVS: The Web Strategy." Harvard Business School Case 500-008, December 1999. (Revised February 2001.) (request a courtesy copy.)
      • 1999
      • Chapter

      The Economics of Drug Discovery

      By: Rebecca M. Henderson and Iain Cockburn
      Keywords: Economics; Innovation and Invention; Research and Development; Pharmaceutical Industry
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      Henderson, Rebecca M., and Iain Cockburn. "The Economics of Drug Discovery." Chap. 5 in Pharmaceutical Innovation, edited by Ralph Landau, Basil Achilladelis, and Alexander Scriabine, 308–331. Philadelphia: Chemical Heritage Press, 1999.
      • June 1999 (Revised October 1999)
      • Case

      Eli Lilly, 1998 (A): Strategic Challenges

      By: Michael Y. Yoshino and Thomas W. Malnight
      Deals with key strategic challenges facing Eli Lilly, a highly successful U.S.-based drug company. View Details
      Keywords: Problems and Challenges; Strategy; Pharmaceutical Industry
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      Yoshino, Michael Y., and Thomas W. Malnight. "Eli Lilly, 1998 (A): Strategic Challenges." Harvard Business School Case 399-173, June 1999. (Revised October 1999.)
      • June 1999 (Revised June 2000)
      • Case

      Eckerd Corporation

      By: Michael E. Porter and John E. Kelleher
      Describes the history and current situation in the retail pharmacy industry, including competition from new merchants and Internet drugstores. Eckerd, one of the top four drug chains, must decide how to position itself for the future. View Details
      Keywords: Competition; Alignment; Supply and Industry; Retail Industry; Pharmaceutical Industry
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      Porter, Michael E., and John E. Kelleher. "Eckerd Corporation." Harvard Business School Case 799-141, June 1999. (Revised June 2000.)
      • March 1999 (Revised June 2000)
      • Case

      Eli Lilly: The Evista Project

      By: Steven C. Wheelwright and Matt Verlinden
      Describes the creation and operation of the initial two heavyweight teams for new drug development and launch. The primary focus is on one of the teams, Evista, although comparisons to the other team, Zyprexa, are included. Lilly must decide the next phase (postlaunch)... View Details
      Keywords: Projects; Groups and Teams; Operations; Management Teams; Product Development; Transition; Product Design; Business Startups; Business Plan; Product Launch; Competition; Service Operations; Pharmaceutical Industry
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      Wheelwright, Steven C., and Matt Verlinden. "Eli Lilly: The Evista Project." Harvard Business School Case 699-016, March 1999. (Revised June 2000.)
      • January 1999
      • Background Note

      Note on the Drugstore Industry

      By: David E. Bell and Ann Leamon
      In response to the twin pressures of cross-channel competition and the prevalence of third-party drug plans, drugstores have changed both how they go to market and what they offer once they get there. This note reviews the history of drugstores, presents the current... View Details
      Keywords: History; Industry Growth; Retail Industry; Pharmaceutical Industry
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      Bell, David E., and Ann Leamon. "Note on the Drugstore Industry." Harvard Business School Background Note 599-079, January 1999.
      • Article

      Absorptive Capacity, Coauthoring Behavior, and the Organization of Research in Drug Discovery

      By: Rebecca M. Henderson and Iain Cockburn
      Keywords: Behavior; Research and Development; Organizations; Health
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      Henderson, Rebecca M., and Iain Cockburn. "Absorptive Capacity, Coauthoring Behavior, and the Organization of Research in Drug Discovery." Journal of Industrial Economics 46, no. 2 (June 1998): 157–182.
      • May 1998
      • Background Note

      Pharma Giants,The: Ready for the 21st Century?

      By: Robert H. Hayes and Perry Fagan
      Presents the changing competitive dynamics in the global pharmaceutical industry and possible implications for large drug companies. View Details
      Keywords: Transformation; Globalized Firms and Management; Competition; Pharmaceutical Industry
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      Hayes, Robert H., and Perry Fagan. "Pharma Giants,The: Ready for the 21st Century?" Harvard Business School Background Note 698-070, May 1998.
      • April 1998
      • Case

      Cephalon, Inc.

      By: Peter Tufano
      In early 1997, Cephalon, awaited an FDA panel's decision on whether its drug, Myotrophin, would be approved. If the drug was approved, the firm might need substantial additional funds to commercialize as well as to buy back rights to it (which had been sold earlier to... View Details
      Keywords: Risk Management; Financing and Loans; Health Care and Treatment; Pharmaceutical Industry; United States
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      Tufano, Peter, Geoffrey Verter, and Markus Mullarkey. "Cephalon, Inc." Harvard Business School Case 298-116, April 1998.
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