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- August 2023
- Case
Constellation Pharmaceuticals: Corporate Development at a Novel Therapeutic Company
By: Satish Tadikonda and Brad Prosek
Constellation Pharmaceuticals was a company focused on epigenetic therapies for cancer patients. Despite a promising start and an early deal with a leading biopharma company, the company weathered twin setbacks in the end of a major research collaboration and the... View Details
- August 2023 (Revised January 2024)
- Case
Jake Becraft and Strand Therapeutics: The Making of an Entrepreneur
By: Satish Tadikonda, William Marks and Ananya Zutshi
Jake Becraft, a PhD student at MIT disillusioned in pursuit of his dreams of becoming an academic, serendipitously finds himself discussing the potential commercial applications of his work with Tasuku Kitada, his former postdoctoral research mentor. The two decide to... View Details
- August 2023
- Article
Anti-Corruption, Government Subsidies, and Innovation: Evidence from China
By: Lily Fang, Josh Lerner, Chaopeng Wu and Qi Zhang
We leverage an exogenous shock—the crackdown on corrupt Chinese officials beginning in 2012—and examine how the allocation of research subsidies and innovative outcomes were affected. We argue that the staggered removal of provincial heads on corruption charges during... View Details
- July–August 2023
- Article
Demand Learning and Pricing for Varying Assortments
By: Kris Ferreira and Emily Mower
Problem Definition: We consider the problem of demand learning and pricing for retailers who offer assortments of substitutable products that change frequently, e.g., due to limited inventory, perishable or time-sensitive products, or the retailer’s desire to... View Details
- August 2023
- Article
Explaining Machine Learning Models with Interactive Natural Language Conversations Using TalkToModel
By: Dylan Slack, Satyapriya Krishna, Himabindu Lakkaraju and Sameer Singh
Practitioners increasingly use machine learning (ML) models, yet models have become more complex and harder to understand. To understand complex models, researchers have proposed techniques to explain model predictions. However, practitioners struggle to use... View Details
- 2023
- Working Paper
How People Use Statistics
By: Pedro Bordalo, John J. Conlon, Nicola Gennaioli, Spencer Yongwook Kwon and Andrei Shleifer
We document two new facts about the distributions of answers in famous statistical problems: they are i) multi-modal and ii) unstable with respect to irrelevant changes in the problem. We offer a model in which, when solving a problem, people represent each hypothesis... View Details
- 2025
- Working Paper
Residential Battery Storage - Reshaping the Way We Do Electricity
By: Christian Kaps and Serguei Netessine
In this paper, we aim to understand when private households invest in behind-the-meter battery storage next to rooftop solar and how those batteries impact households, the electricity market, and emissions. We answer three main research questions: 1) When do customers... View Details
- August 2023
- Article
What About the Race Between Technology and Education in the Global South? Comparing Skill-premiums in Colonial Africa and Asia
By: Ewout Frankema and Marlous van Waijenburg
Historical research on the race between education and technology has focused on the West but barely touched upon ‘the rest’. A new occupational wage database for 50 African and Asian economies allows us to compare long-run patterns in skill premiums across the colonial... View Details
- July 2023
- Case
DayTwo: Going to Market with Gut Microbiome (Abridged)
By: Ayelet Israeli
DayTwo is a young Israeli startup that applies research on the gut microbiome and machine learning algorithms to deliver personalized nutritional recommendations to its users in order to minimize blood sugar spikes after meals. After a first year of trial rollout in... View Details
- July 2023
- Technical Note
Agricultural Innovation and Sustainability in the Netherlands
By: Willy C. Shih, Michael W. Toffel, Kelsey Carter, Jennifer Godfrey, Rafaella Mazza and Katrina Yeh
This note describes some of the most significant agricultural innovations in the Netherlands, their drivers, environmental performance implications, some challenges facing the sector, and the potential replicability of these innovations to other contexts. View Details
- 18 Jul 2023
- Interview
Jeffrey Rayport on Product Market Fit, Profit Market Fit and Whiplash, and More
By: Jeffrey F. Rayport and Doug Levin
This episode of "Lessons from Startup Life" podcast features Jeffrey Rayport, Senior Lecturer of Business Administration at the Harvard Business School. Jeffrey specializes in teaching and researching growth-stage technology ventures and their scalability. Prior to... View Details
- July 2023
- Article
Negative Expressions Are Shared More on Twitter for Public Figures Than for Ordinary Users
By: Jonas P. Schöne, David Garcia, Brian Parkinson and Amit Goldenberg
Social media users tend to produce content that contains more positive than negative emotional language. However, negative emotional language is more likely to be shared. To understand why, research has thus far focused on psychological processes associated with... View Details
- 2024
- Working Paper
Anti-Political-Establishment Citizens: An In-Depth Study from Two Latin American Countries
By: Loreto Cox and Natalia Garbiras-Diaz
Building on citizens’ animosity towards politicians, anti-establishment parties and
candidates have achieved significant electoral success. While recent studies examine
the supply-side, we know little about what drives citizens’ anti-establishment sentiments and how... View Details
- July 2023
- Article
Design and Analysis of Switchback Experiments
By: Iavor I Bojinov, David Simchi-Levi and Jinglong Zhao
In switchback experiments, a firm sequentially exposes an experimental unit to a random treatment, measures its response, and repeats the procedure for several periods to determine which treatment leads to the best outcome. Although practitioners have widely adopted... View Details
- June 2023 (Revised November 2024)
- Case
Albert Einstein: Changing the World
By: Robert Simons and Shirley Sun
This case traces the rise of Albert Einstein from a small town in Germany to a towering intellectual leader who revolutionized the field of physics. The case describes his early education and his penchant for individual thinking and non-conformity. A committed... View Details
- June 2023
- Case
Investing in the Climate Transition at Neuberger Berman
By: George Serafeim and Benjamin Maletta
By mid-2023, Neuberger Berman (NB), an active asset manager, had grown its assets under management to about half a trillion dollars and took pride in its client centricity and innovative spirit. Responding to client demand for investment products that integrated... View Details
Keywords: Carbon Emissions; Sustainability; Decarbonization; Performance; Risk Assessment; Opportunities; Environmental Sustainability; Carbon Footprint; Business Analysis; Investing; Regulation; Asset Management; Investment Strategy; Climate Change; Transition; Analysis; Product Positioning; Strategy; Investment Portfolio; Financial Services Industry; Energy Industry
- June 14, 2023
- Article
Research: Your Love for Work May Alienate Your Colleagues
By: Mijeong Kwon, Julia Lee Cunningham and Jon M. Jachimowicz
Research shows that employees who are passionate about their work are more productive, innovative, and collaborative. New research suggests that these employees also see passion for work as a moral imperative, and they’re more likely to judge colleagues who are... View Details
- 2023
- Working Paper
Evaluation and Learning in R&D Investment
By: Alexander P. Frankel, Joshua L. Krieger, Danielle Li and Dimitris Papanikolaou
We examine the role of spillover learning in shaping the value of exploratory versus incremental
R&D. Using data from drug development, we show that novel drug candidates generate more
knowledge spillovers than incremental ones. Despite being less likely to reach... View Details
- 2023
- Working Paper
Design-Based Confidence Sequences: A General Approach to Risk Mitigation in Online Experimentation
By: Dae Woong Ham, Michael Lindon, Martin Tingley and Iavor Bojinov
Randomized experiments have become the standard method for companies to evaluate the performance of new products or services. In addition to augmenting managers’ decision-making, experimentation mitigates risk by limiting the proportion of customers exposed to... View Details
- June 2023
- Article
Can Purpose Foster Stakeholder Trust in Corporations
By: Ranjay Gulati and Franz Wohlgezogen
As part of institutional changes toward more responsible capitalism, firms increasingly articulate a purpose beyond simply profit as a central tenet of their governance. Management scholarship has noted the potential advantages of such purpose-focus for stakeholder... View Details