Medical Innovations - Publications - Faculty & Research

February 2021 (Revised June 2021)
Case

Brainlab: Imaging a MedTech Future

By: Regina E. Herzlinger, Gregory P. Licholai and Federica Gabrieli

Can Brainlab, a privately held firm, compete with giants like Medtronic and Amazon in delivering the Digital Operating Room of the future? The CEO is pondering solutions for secure exchange of medical information, pricing a new robotic imaging device, and reorganizing... View Details

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01 Apr 2014
First Look

First Look: April 1

organizational processes of developing a business model. Download working paper: https://www.hbs.edu/faculty/Pages/item.aspx?num=46978 The Liability of Leakage: How Indirect Ties to Competitors Impact Innovation in Entrepreneurial Firms... View Details

Keywords: Sean Silverthorne

April 2006
Case

Adrian Ivinson at the Harvard Center for Neurodegeneration and Repair

By: Robert Steven Kaplan and Ayesha Kanji

Adrian Ivinson is the director of Harvard Center for Neurodegeneration and Repair (HCNR), a not-for-profit research center at the Harvard Medical School (HMS). The center was started in late 2000 with a gift of $37.5 million from an anonymous donor. Its mandate was to... View Details

Keywords: Leadership Style; Power and Influence; Organizational Culture; Research and Development; Nonprofit Organizations; Motivation and Incentives; Change Management; Alignment; Collaborative Innovation and Invention; Health Industry; Massachusetts

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11 Nov 2015
Working Paper Summaries

Public R&D Investments and Private-sector Patenting: Evidence from NIH Funding Rules

Keywords: by Danielle Li; Medical Devices & Supplies; Medical Devices & Supplies; Medical Devices & Supplies; Medical Devices & Supplies

21 Apr 2009
First Look

First Look: April 21, 2009

consumption fluctuations faced by individuals, households, and firms. Yet much of this promise remains unrealized. In this paper, we study the adoption of an innovative rainfall insurance product designed to compensate low-income Indian... View Details

Keywords: Martha Lagace

22 Jul 2014
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First Look: July 22

use process mapping and time-driven activity-based costing to measure the costs of treating patients over a complete cycle of care for a specific medical condition. With valid outcome and cost information, managers and clinicians can... View Details

Keywords: Sean Silverthorne

February 2024
Article

Representation and Extrapolation: Evidence from Clinical Trials

By: Marcella Alsan, Maya Durvasula, Harsh Gupta, Joshua Schwartzstein and Heidi L. Williams

This article examines the consequences and causes of low enrollment of Black patients in clinical trials. We develop a simple model of similarity-based extrapolation that predicts that evidence is more relevant for decision-making by physicians and patients when it... View Details

Keywords: Representation; Racial Disparity; Health Testing and Trials; Race; Equality and Inequality; Innovation and Invention; Pharmaceutical Industry

20 May 2013
Op-Ed

Making America an Industrial Powerhouse Again

As part of his administration's strategy to rejuvenate American manufacturing, President Obama has called for the creation of a National Network of Manufacturing Innovation (NNMI) to advance and diffuse novel manufacturing technologies.... View Details

Keywords: by Gary Pisano; Manufacturing

2020
Book

Fit to Compete: Why Honest Conversations About Your Company's Capabilities Are the Key to a Winning Strategy

By: Michael Beer

Is Silence Killing Your Strategy?
In his thirty years of working in corporations, Harvard Business School professor Michael Beer has witnessed firsthand how organizational silence derails strategic objectives. When employees can't speak truth to power, senior... View Details

Keywords: Honesty; Communication; Organizational Culture; Trust; Strategy; Performance Effectiveness

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August 2017
Case

RoboTech: Storming into the U.S. Market

By: Christopher A. Bartlett, Rachel Gordon and John J. Lafkas

This case describes the challenges facing the CEO of a small, Singapore-based industrial robotics company that decides to diversify away from its core industrial robot business by leveraging its expertise into the medical-devices industry. It launches an innovative... View Details

Keywords: Market Entry and Exit; Diversification; Product Launch; Competitive Strategy; Globalized Firms and Management; Medical Devices and Supplies Industry; Medical Devices and Supplies Industry; Singapore; United States

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January 2022
Case

Somatus: Value-Based Kidney Care (A)

By: Ariel D. Stern, Robert S. Huckman and Sarah Mehta

When Dr. Ikenna Okezie founded Somatus, a value-based kidney care provider, his goal had been nothing short of transforming kidney care delivery in the United States. Rather than relying on dialysis, a costly and intensive treatment for late-stage kidney disease, the... View Details

Keywords: Business Startups; Disruption; Entrepreneurship; Health; Health Care and Treatment; Health Disorders; Medical Specialties; Innovation and Invention; Disruptive Innovation; Management; Strategy; Business Strategy; Value; Value Creation; Health Industry; United States; Virginia

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12 Jul 2020
Research & Ideas

Solving COVID'S Mental Health Crisis

encouraged and instructed teens how to safely dispose of unused prescription medications in their homes. “Several thousand teens participated online or watched replays,” Langford says. SUD treatment providers are also searching for ways... View Details

Keywords: by Howard Stevenson and Shirley Spence; Health

November 2022
Teaching Note

Proximie: Using XR Technology to Create Borderless Operating Rooms

By: Ariel D. Stern, Alpana Thapar and Menna Hassan

Founded by Nadine Hachach-Haram in 2016, Proximie was a digital medicine platform that used mixed reality and a host of digital audio and visual tools to enable clinicians, proctors, and medical device company personnel to be virtually present in operating rooms (ORs),... View Details

Keywords: Technological Innovation; Business Growth and Maturation; Growth and Development Strategy; Corporate Social Responsibility and Impact; Decision Making; Medical Devices and Supplies Industry; Medical Devices and Supplies Industry

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Article

A Field Experiment on Search Costs and the Formation of Scientific Collaborations

By: Kevin Boudreau, Tom Brady, Ina Ganguli, Patrick Gaule, Eva C. Guinan, Anthony Hollenberg and Karim R. Lakhani

We present the results of a field experiment conducted at Harvard Medical School to understand the extent to which search costs affect matching among scientific collaborators. We generated exogenous variation in search costs for pairs of potential collaborators by... View Details

Keywords: Search Costs; Cost; Marketplace Matching; Groups and Teams; Science; Collaborative Innovation and Invention

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June 2023
Case

Verve Therapeutics: Taking DNA Editing to Heart

By: Shikhar Ghosh and Shweta Bagai

Verve Therapeutics, a public biotech company based in Boston, created a novel approach to addressing cardiovascular disease (CVD) - a leading cause of deaths globally. The company's approach was a single shot treatment to permanently lower cholesterol, thus reducing... View Details

Keywords: AI; Genetic Engineering; Medicine; Health Care and Treatment; Genetics; Innovation Strategy; Business and Stakeholder Relations; Medical Specialties; Innovation and Invention; Entrepreneurship; Biotechnology Industry

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01 Sep 2009
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First Look: September 1

649-651 Abstract In my second week of medical internship, I received a "friend request" on Facebook, the popular social-networking Web site. The name of the requester was familiar: Erica Baxter. Three years earlier, as a View Details

Keywords: Martha Lagace

03 May 2010
Research & Ideas

What Is the Future of MBA Education?

the limitations of models and markets. At these crossroads, how should business education proceed? We wrote the book to outline the needs and to explain how schools are addressing them in surprisingly innovative ways. We include in-depth... View Details

Keywords: by Martha Lagace; Education

21 Feb 2012
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First Look: Feb. 21

information is a central determinant of a firm's demand function, even for purchases as large as college attendance. When Do User Innovators Start Firms? A Theory of User Entrepreneurship Authors:Sonali Shah and Mary Tripsas... View Details

Keywords: Sean Silverthorne

December 2003
Case

Sale of Hephaestus, Inc. to Vulcan Ventures, Inc.

Henry Hephaestus founded Hephaestus, Inc. in 1895. Its first product was a tapered roller bearing for use with horse-drawn wagons and carriages. It reduced friction on the axle and reduced the force necessary to move a heavy load, thereby enabling one horse to do the... View Details

Keywords: Business Exit or Shutdown; Entrepreneurship; Family Ownership; Manufacturing Industry

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