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2003
Chapter

Short-Term America Revisited? Boom and Bust in the Venture Capital Industry and the Impact on Innovation

By: Josh Lerner and Paul A. Gompers

This chapter seeks to understand the implications of the recent decline in venture activity for innovation. It argues that the situation may not be as grim as it initially appears. While there are many reasons for believing that on average venture capital has a... View Details

Keywords: Venture Capital; Innovation and Invention; Business Cycles; Financial Services Industry; United States

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June 2018
Article

Cost of Experimentation and the Evolution of Venture Capital

By: Michael Ewens, Ramana Nanda and Matthew Rhodes-Kropf

We study how technological shocks to the cost of starting new businesses have led the venture capital model to adapt in fundamental ways over the prior decade. We both document and provide a framework to understand the changes in the investment strategy of VCs in... View Details

Keywords: Innovation; Investing; Abandonment Option; Technological Innovation; Venture Capital; Investment

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Teaching Interest

Economics of Entrepreneurship and Venture Capital

Designed for Harvard College sophomores.

Course Description: Why do so many individuals choose to pursue entrepreneurship despite substantial risks? How do these entrepreneurs raise money to finance their ventures? And what is the impact of... View Details

Keywords: Entrepreneurship; Entrepreneurial Finance; Entrepreneurship And Strategy; Venture Capital

November 2016 (Revised May 2017)
Case

Hyperloop One

By: William A. Sahlman, Ramana Nanda, Robert White, Allison Ciechanover and Jeff Huizinga

This case explores the attempt of Shervin Pishevar, a prominent Silicon Valley investor, to shepherd hyperloop, a futuristic pod-in-tube transportation technology, from concept to transformative reality via Hyperloop One and Sherpa Capital, both companies he... View Details

Keywords: Entrepreneurial Finance; Startup; Entrepreneurship; Business Startups; Finance; Transportation; Product Development; Innovation and Invention; Transportation Industry

April 5, 2023
Article

We Need an Operation Warp Speed for Long COVID

By: Esther K. Choo and Scott Duke Kominers

With millions of people affected and at least $1 trillion of economic value at stake, long COVID is our next national health emergency. View Details

Keywords: COVID; COVID-19; COVID-19 Pandemic; Scientific Research; Policy; Health Policy; Innovation; Science; Public Finance; Public Health; Health Disorders; Health Care and Treatment; Human Capital

Article

Lessons From Hollywood: A New Approach To Funding R&D

By: Gary P. Pisano and Andrew W. Lo

Companies find it increasingly difficult to justify long-term, risky R&D investments—particularly in science-based fields such as biotechnology, advanced materials, and energy. We argue in this article that the traditional venture model has limits for such investments... View Details

Keywords: Financial Innovation; Financial Strategy; Project Management; R＆D; Start-up; Innovation Strategy; Business Model; Research and Development; Financial Management; Risk Management; Strategy

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August 2017 (Revised June 2018)
Case

Enpara.com: Digital Bank at a Crossroad

By: Sunil Gupta and Eren Kuzucu

In March 2017, Elsa Pekmez Atan (MBA 2004), was wondering about the future of Enpara.com, a digital-only banking platform of QNB Finansbank. Since its launch in October 2012, Enpara had been successful in attracting over 600,000 customers by appealing to digital savvy,... View Details

Keywords: Innovation; Competition; Banks and Banking; Business Model; Product Launch; Competitive Strategy; Integration; Innovation and Invention; Decision Making; Strategy; Emerging Markets; Digital Transformation; Banking Industry; Turkey

April 2022 (Revised May 2022)
Case

Mastercard Labs (A)

By: Linda A. Hill, Sunil Gupta, Emily Tedards and Julia Kelley

When Ajaypal (Ajay) Banga became the CEO of Mastercard in 2010, he shifted the company’s competitive focus from card networks to cash itself. Mastercard’s new vision of a “World Beyond Cash” distilled into a three-pronged framework: Grow the core business, Diversify... View Details

2018
Article

Threat of Platform-Owner Entry and Complementor Responses: Evidence from the Mobile App Market

By: Wen Wen and Feng Zhu

We examine how app developers on the Android mobile platform adjust their innovation efforts (rate and direction) and value-capture strategies in response to Google’s entry threat and actual entry into their markets. We find that, after Google’s entry threat increases,... View Details

Keywords: Platform-owner Entry; Entry Threat; Innovation; Complementors; Mobile App Industry; Digital Platforms; Mobile and Wireless Technology; Market Entry and Exit; Price; Innovation and Invention; Applications and Software

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October 2012 (Revised March 2022)
Case

Kleiner-Perkins and Genentech: When Venture Capital Met Science

By: Felda Hardymon and Tom Nicholas

Genentech is a rare success story in the biotechnology industry. Hundreds of billions of dollars of venture capital have been invested without the expected transformational effects. Established in 1976, Genentech was to develop the new science of recombinant DNA into... View Details

Keywords: Innovation ＆ Entrepreneurship; Venture Capital; Innovation and Invention; Entrepreneurship; Information Technology; Science; Biotechnology Industry; United States

March 2019 (Revised October 2020)
Case

GENTERA: Facing the Digital Age

By: Michael Chu and Carla Larangeira

After long dominating Mexican microfinance, Compartamos Banco faces the emergence of fintech, just as for the first time its loan portfolio and clients have declined. Enrique Majós, CEO of GENTERA, the bank´s parent company, is keenly aware of the profound changes... View Details

Keywords: Micro Finance; Base Of The Pyramid; Fintech; Microfinance; Disruption; Innovation and Management; Competitive Strategy; North America; Mexico

March 2016 (Revised May 2021)
Case

Michael Milken: The Junk Bond King

By: Tom Nicholas and Matthew G. Preble

Michael Milken, an investment banker who dominated the junk bond market in the 1980s, was sentenced to jail in 1990 after pleading guilty to a number of securities and tax-related felonies. In the preceding decade, Milken had helped usher in a new wave of leveraged buy... View Details

Keywords: Junk Bonds; High-yield Bonds; Financial Innovation; Shareholder Value; Bonds; Capital; Capital Structure; Cost of Capital; Crime and Corruption; Entrepreneurship; Ethics; Finance; Investment Banking; Leveraged Buyouts; Mergers and Acquisitions; Ownership; Private Equity; Restructuring; United States

June 2014
Article

The Capitalist's Dilemma

By: Clayton M. Christensen and Derek C. M. van Bever

Sixty months after the 2008 recession ended, the economy was still sputtering, producing disappointing growth and job numbers. Corporations seemed stuck: Despite low interest rates, they were sitting on massive piles of cash and failing to invest in new initiatives. In... View Details

Keywords: Capital Investments; Creating Markets; Evaluating Business Investments; Innovation; Emerging Markets; Investment; Economic Growth; Capital; Innovation and Invention

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March 2016
Teaching Note

Advanced Leadership Pathways: Inge Skjelfjord and the Cacao Supply Chain

By: Rosabeth Moss Kanter and Ai-Ling Jamila Malone

Inge Skjelfjord, with a long career in international finance focused on agribusiness projects, had a vision to build a cacao research center that would help smallholder cacao farmers, who benefited the least from the chocolate value chain. He aimed to support the... View Details

Keywords: Agribusiness Industry; Farming; Farm; Policy; Change Management; Innovation; Agribusiness; Education; Economic Growth; Research; Supply Chain; Supply Chain Management; Agriculture and Agribusiness Industry; Ecuador

Teaching Interest

Overview

By: Regina E. Herzlinger

Course Requirements

Students are required to prepare a business plan, which employs the framework of this course, to explore an entrepreneurial opportunity in health care, and to evaluate their classmates' plans.

Career Focus

For... View Details

Keywords: Healthcare; Healthcare Industry; Healthcare Innovation; Healthcare Costs; Healthcare Operations; Healthcare Organizations; Healthcare Startups; Healthcare Technology; Healthcare Ventures

April 2016 (Revised June 2019)
Case

The Walt Disney Studios

By: Anita Elberse

In December 2015, Alan Horn, chairman of The Walt Disney Studios, celebrates the world premiere of Star Wars: The Force Awakens—only the latest in a string of big bets that he has overseen. Disney pursues a “tentpole strategy” that revolves around at least eight... View Details

February 2025
Article

Innovations in Evaluating Ambulatory Costs of Cystic Fibrosis Care: A Comparative Study Across Multidisciplinary Care Centers in Ireland and the United States

By: Emma Brady, Ryan C. Perkins, Kate Cullen, Gregory S. Sawicki, Robert S. Kaplan and Gerardine Doyle

Lead clinicians at two large pediatric cystic fibrosis (CF) centers in the United States and Ireland measured and compared their ambulatory care costs. The clinicians selected three strata of patients (0–11 months, 1–5 years, and 6–17 years of age). Process maps were... View Details

Keywords: Health Care and Treatment; Cost; Service Delivery; Resource Allocation; Health Industry

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November 2016 (Revised May 2017)
Case

The Black List

By: Henry McGee and Sarah McAra

Franklin Leonard founded The Black List in 2005 as an innovative approach to identifying potential hit movie scripts via crowdsourcing. As the annual Black List proved to hold the scripts of some of Hollywood’s most successful films, from “Slumdog Millionaire” to... View Details

Keywords: Screenwriting; Independent Production; Hollywood; Film Development; Film Distribution; Film Financing; Manging Uncertainty; Barriers To Entry; Globalization; Digitalization; Film Entertainment; Entrepreneurship; Marketing; Media; Strategy; Motion Pictures and Video Industry; United States

15 May 2012
Panel Discussion

Capitalism at Risk

By: Lynn S. Paine and Joseph L. Bower

Keywords: Capital Markets; Innovation; Capital Structure; Innovation Leadership; Consumer Products Industry

Editorial

ESG Returns Eventually Will Win Over Critics

By: George Serafeim

Keywords: ESG; ESG (Environmental, Social, Governance) Performance; ESG Reporting; Sustainability; Change; Change Management; Innovation; Environment; Climate Change; Sustainable Finance; Investment

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