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Kraft Accelerator

The Harvard Business School Kraft Precision Medicine Accelerator convenes best-in-class leaders from the business, medical, scientific, and technological communities to identify and solve challenges slowing the advancement of precision medicine,... View Details
  • 2019
  • Chapter

Characterizing the Drug Development Pipeline for Precision Medicines

By: Amitabh Chandra, Craig Garthwaite and Ariel Dora Stern
BOOK ABSTRACT: Personalized and precision medicine (PPM)—the targeting of therapies according to an individual’s genetic, environmental, or lifestyle characteristics—is becoming an increasingly important approach in health care treatment and prevention. The advancement... View Details
Keywords: Healthcare; Precision Medicine
Related
  • September 2017 (Revised February 2023)
  • Case

Intermountain Healthcare: Pursuing Precision Medicine

By: Richard G. Hamermesh, Kathy E. Giusti, Robert S. Huckman and Julia Kelley
Headquartered in Salt Lake City, Intermountain Healthcare operates 23 hospitals and hundreds of clinics in Utah and Idaho and provides insurance to approximately 850,000 patients through its insurance arm, SelectHealth. In 2013, Intermountain, known for its commitment... View Details
Keywords: Precision Medicine; Healthcare; Innovation; Cancer; Cancer Research; Health Care; Technology; Health Care and Treatment; Innovation Leadership; Disruptive Innovation; Entrepreneurship; Decision Choices and Conditions; Health Industry; Insurance Industry; Utah; United States; North America
Related
  • June 2020
  • Case

Breakthroughs at Blueprint Medicines

By: Richard G. Hamermesh, Kathy Giusti and Susie L. Ma
Precision medicine company Blueprint Medicines was building a successful track record for bringing drug therapies to market 40% faster than average. The company had spent $40 million dollars and two years building a compound library that became its drug development... View Details
Keywords: Precision Medicine; Cancer; Biotechnology; Drug Development; Strategy; Expansion; Science; Genetics; Information Technology; Entrepreneurship; Organizational Culture; Management; Growth and Development; Pharmaceutical Industry; United States; Cambridge; Massachusetts
Related
  • 28 Feb 2019
  • Cold Call Podcast

Pursuing Precision Medicine at Intermountain Healthcare

Keywords: Re: Richard G. Hamermesh; Health; Biotechnology; Pharmaceutical
  • March 17, 2017
  • Article

How Economics Can Shape Precision Medicines

By: Ariel Dora Stern, Brian M. Alexander and Amitabh Chandra
Many public and private efforts in coming years will focus on research in precision medicine, developing biomarkers to indicate which patients are likely to benefit from a certain treatment so that others can be spared the cost—financial and physical—of being treated... View Details
Keywords: Health Care and Treatment; Research; Economics; Motivation and Incentives
Related
  • July 2019 (Revised July 2019)
  • Teaching Note

Intermountain Healthcare: Pursuing Precision Medicine

By: Richard G. Hamermesh, Robert S. Huckman and Julia Kelley
Related
  • 28 Feb 2019
  • Interview

Pursuing Precision Medicine at Intermountain Healthcare

By: Richard G. Hamermesh and Brian Kenny
Related
  • Article

How Harvard Business School Is Advancing Precision Medicine

By: Kathy Giusti and Richard G. Hamermesh
Related
  • April 13, 2017
  • Article

What Precision Medicine Can Learn from the NFL

By: Richard G. Hamermesh and Kathryn E. Giusti
Related
  • October 4, 2018
  • Article

Precision Medicine Needs a Business Mindset in Order to Flourish

By: Richard G. Hamermesh and Kathryn E. Giusti
Related
  • November 12, 2018
  • Article

Precision Medicine Has Transformed Cancer Treatment. Here's How to Move It Beyond Oncology

By: Richard G. Hamermesh and Kathy Giusti
Related
  • Article

One Obstacle to Curing Cancer: Patient Data Isn't Shared

By: Richard G. Hamermesh and Kathy Giusti
Precision Medicine requires large datasets to identify the mutations that lead to various cancers. Currently, genomic information is hoarded in fragmented silos within numerous academic medical centers, pharmaceutical companies, and some disease-based foundations. For... View Details
Keywords: Healthcare; Technological And Scientific Innovation; Cancer Care In The U.S.; Cancer Treatment; Precision Medicine; Personalized Medicine; Data Sharing; Technological Innovation; Analytics and Data Science; Health Disorders; Medical Specialties; Research and Development; Customization and Personalization; Health Industry; United States
Related
  • 2023
  • Article

Experimental Evaluation of Individualized Treatment Rules

By: Kosuke Imai and Michael Lingzhi Li
The increasing availability of individual-level data has led to numerous applications of individualized (or personalized) treatment rules (ITRs). Policy makers often wish to empirically evaluate ITRs and compare their relative performance before implementing them in a... View Details
Keywords: Causal Inference; Heterogeneous Treatment Effects; Precision Medicine; Uplift Modeling; Analytics and Data Science; AI and Machine Learning
Related
  • 15 Jan 2018
  • Research & Ideas

A Better Business Model for Fighting Cancer

iPhoto With billions of dollars spent on the development of precision medicine and related cancer research over the last decade, a recent partnership seeks a new way to bring these treatments to patients... View Details
Keywords: by Julia Hanna; Health; Pharmaceutical
  • 11 Apr 2017
  • First Look

First Look at New Research, April 11

different innovation policies can help to explain who finances radical innovations and when and where radical innovation occurs. Publisher's link: https://www.hbs.edu/faculty/Pages/item.aspx?num=52506 March 17, 2017 Science How Economics Can Shape View Details
  • 19 Dec 2017
  • First Look

New Research and Ideas, December 19, 2017

Abstract—No abstract available. Publisher's link: https://www.hbs.edu/faculty/Pages/item.aspx?num=53633 Characterizing the Drug Development Pipeline for Precision Medicines By: Chandra, Amitabh, Craig... View Details
Keywords: Carmen Nobel
  • 21 Apr 2009
  • First Look

First Look: April 21, 2009

two-sided proprietary (closed) platforms connecting consumers and producers. Proprietary platforms create two-sided deadweight losses through monopoly pricing but at the same time, precisely because they set prices in order to maximize... View Details
Keywords: Martha Lagace
  • 19 Jan 2023
  • Research & Ideas

What Makes Employees Trust (vs. Second-Guess) AI?

holds in higher stakes settings such as medical diagnosis and treatment or credit lending.” That finding may be useful across industries from transportation to medicine as AI evolves and the quality—and quantity—of data climbs, DeStefano... View Details
Keywords: by Rachel Layne
  • 21 Aug 2000
  • Research & Ideas

Inside the OR: Disrupted Routines and New Technologies

process matter greatly for an organization's ability to learn in response to external innovation." In undertaking their study, Edmondson, Bohmer and Pisano drew on their respective expertise in organizational behavior, medicine and... View Details
Keywords: by Hilah Geer

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