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  • September 2013 (Revised August 2014)
  • Case

Claritas Genomics

By: Robert F. Higgins and Matthew Preble
Claritas Genomics was formed in January 2013 when BCH spun out its Genetics Diagnostic Lab into a fully commercial entity. Claritas offered over 100 genomic tests to detect a range of conditions, including autism and intellectual disabilities, and was developing new... View Details
Keywords: Boston Children's Hospital; Genetic Engineering; Genetically Modified; Genetics Diagnostics; Health Care Industry; Healthcare IT; Healthcare Technology; Healthcare Ventures; Biomedical Research; Patrice Milos; Genomics; Genomic Testing; Life Technologies; Health Care and Treatment; Information Technology; Information Management; Genetics; Biotechnology Industry; Information Technology Industry; Health Industry; Boston; Massachusetts; United States
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  • November 2014
  • Teaching Note

Claritas Genomics

By: Robert F. Higgins and Matthew G. Preble
Dr. Patrice Milos is the first CEO of Claritas Genomics (Claritas) and she faces a number of challenges in scaling the young company. Claritas was formed around a lab spun out from Boston Children's Hospital (BCH) which had performed genomic tests for the hospital. Now... View Details
Keywords: Healthcare; Healthcare Startups; Genetic Testing; Genetics Diagnostics; Spinning Out Hospital Services; Spin-out; Health Care and Treatment; Genetics; Entrepreneurship; Biotechnology Industry; Health Industry; United States
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  • October 2008
  • Case

Diagnostic Genomics

By: Regina E. Herzlinger and Mark P. Allyn
Should this gene detection firm enter the business of providing tests for the detection of genetic diseases? If so, how should it prioritize the tests it could develop? View Details
Keywords: Health Testing and Trials; Market Entry and Exit; Product Development; Genetics; Strategy; Health Industry; Medical Devices and Supplies Industry
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  • January 2014 (Revised June 2014)
  • Case

23andMe: Genetic Testing for Consumers (A)

By: John A. Quelch and Margaret L. Rodriguez
On November 22, 2013, the direct-to-consumer genetic testing provider, 23andMe, received a letter from the U.S. Food and Drug Administration (FDA) ordering the company to halt the sale and promotion of its genetic testing kit. The FDA stated that the product was... View Details
Keywords: Public Health; Genome Testing; Health Care; Ancestry; 23andMe; Marketing; Product Launch; Health; Health Care and Treatment; Health Testing and Trials; Genetics; Strategy; Health Industry; United States
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  • January 2014 (Revised December 2014)
  • Case

GenapSys: Business Models for the Genome

By: Richard G. Hamermesh, Joseph B. Fuller and Matthew Preble

GenapSys, a California-based startup, was soon to release a new DNA sequencer that the company's founder, Hesaam Esfandyarpour, believed was truly revolutionary. The sequencer would be substantially less expensive—potentially costing just a few thousand dollars—and... View Details

Keywords: DNA Sequencing; Life Sciences; Business Model; Innovation ＆ Entrepreneurship; Health Care and Treatment; Genetics; Business Strategy; Biotechnology Industry; Pharmaceutical Industry; Technology Industry; Health Industry; Medical Devices and Supplies Industry; United States
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  • May 2009 (Revised August 2013)
  • Case

The DiagnoFirst Opportunity

By: Robert C. Pozen and Rukmini Balu
John Mason, a principle at Oldwell Partners, was facing a decision of whether or not to invest in DiagnoFirst, a molecular diagnostics firm. DiagnoFirst's key product was a genetic test that identified a subset of prostate cancer patients with a high risk of clinical... View Details
Keywords: Genetic Engineering; Genetically Modified; Genomics; Venture Capital; Patents; Genetics; Decision Choices and Conditions; Laws and Statutes; Investment; Science-Based Business; Biotechnology Industry
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  • 30 Mar 2020
  • News

Why Is the U.S. Behind on Coronavirus Testing?

  • September 2017 (Revised February 2023)
  • Case

Intermountain Healthcare: Pursuing Precision Medicine

By: Richard G. Hamermesh, Kathy E. Giusti, Robert S. Huckman and Julia Kelley
Headquartered in Salt Lake City, Intermountain Healthcare operates 23 hospitals and hundreds of clinics in Utah and Idaho and provides insurance to approximately 850,000 patients through its insurance arm, SelectHealth. In 2013, Intermountain, known for its commitment... View Details
Keywords: Precision Medicine; Healthcare; Innovation; Cancer; Cancer Research; Health Care; Technology; Health Care and Treatment; Innovation Leadership; Disruptive Innovation; Entrepreneurship; Decision Choices and Conditions; Health Industry; Insurance Industry; Utah; United States; North America
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  • Web

Curriculum - MBA

appropriate informed consent for genomic testing and direct-to-consumer offers of personal genomic testing, including the return of incidental findings. Biological Chemistry &... View Details
  • 21 Jan 2014
  • First Look

First Look: January 21

out its Genetics Diagnostic Lab into a fully commercial entity. Claritas offered over 100 genomic tests to detect a range of conditions, including autism and intellectual disabilities, and was developing new... View Details
Keywords: Sean Silverthorne
  • 01 Mar 2024
  • News

On the Radar

Illustration by Brian Stauffer Illustration by Brian Stauffer Our planet is teeming with trillions of viruses and bacteria, most of which are innocuous or even helpful, but some pose a significant risk to public health, animals, and crops. In recent decades,... View Details
Keywords: Janine White; Justice, Public Order, and Safety Activities; Government
  • 13 Jan 2009
  • First Look

First Look: January 13, 2009

structurally attractive for soft drink firms, and b) if so, how can Pepsi best "catch-up" with Coca-Cola in a given market. Purchase this case: http://harvardbusinessonline.hbsp.harvard.edu/ b01/en/common/item_detail.jhtml?id=709451 Diagnostic View Details
Keywords: Martha Lagace
  • Web

Advisory Board - Entrepreneurship

Wildfire Communications, a telecommunications software venture backed by Matrix Partners and Greylock Management. From 1977 to 1994, Joe was a Vice President of Teradyne (NYSE/ automatic test equipment) and a member of its Management... View Details
  • 01 Jun 2023
  • News

From Big Pharma to Startup

Hunter Goble (MBA 2022) did not enroll in Harvard Business School with dreams of becoming an entrepreneur. After earning his MBA, Goble intended to return to Eli Lilly to continue to work building brands and launching products. He envisioned himself leading a big,... View Details
Keywords: April White
  • Web

Rare Disease Day – Small Numbers, Big Challenges… and Big Opportunities - Blog: Health Supplement

Thanks to her relentless efforts, we are part of the fortunate few that have been properly genetically tested and diagnosed. While rare, HHT is the second most common inherited bleeding disorder, and yet despite its prevalence, it is... View Details
  • 04 Sep 2019
  • News

Advancing Diagnostics that Can Save Lives

tools, expediting the time frame and accuracy of results. Using genomics and machine learning, Day Zero Diagnostics (DZD) and Aikili Biosystems aim to save lives. “A common reaction to our venture is that it is ‘ambitious.’ Clearly our... View Details
Keywords: Susan Young
  • 29 May 2001
  • Research & Ideas

Genomics: Can We Start Making Money Now?

has only about 30,000 genes—far fewer than was previously believed. What's more, the genetic difference between people, indeed, between people and animals, is relatively small. Genomics is the most destructive force in the history of... View Details
Keywords: by Sean Silverthorne
  • 20 Jul 2017
  • News

Life Lab Nurtures Early Stage Startup Day Zero Diagnostics

Melis Anahtar in the Life Lab If you’ve ever been hospitalized with an infection and had to wait days for test results and a treatment plan, you understand the problems that Day Zero Diagnostics (DZD) is addressing. The company is one of... View Details
Keywords: Scientific Research and Development Services
  • 01 Dec 2018
  • News

Case Study: Your Data, Your Health

Ridhi Tariyal (MBA 2009) was in her early 30s when she grew curious about her chances of having children one day. “I didn’t want to wake up and learn that my opportunity had passed,” says Tariyal, then a genomics researcher with a... View Details
Keywords: Jen McFarland Flint
  • Web

Kraft Accelerator

trials and research, and how the challenges go way beyond just making the technology work. Previous Episodes Bridging a Critical Gap: Using AI to Avoid Wasteful Treatments, Unnecessary Tests and Poor Outcomes 19 SEP 2019 | Under the... View Details