Gene Sequencing - Publications - Faculty & Research - Harvard Business School

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October 2011
Case

Gene Sequencing: Staking a Position in an Expanding Industry

By: Richard G. Hamermesh, Mara Aspinall and Phillip Andrews

Towards the end of 2010, companies in the gene sequencing industry were pushing aggressive R&D programs to develop technologies and products in the race to sequence the entire human genome at a cost of $1,000. It remained to be seen when the "$1,000 genome" would... View Details

Keywords: Genetics; Business Growth and Maturation; Business Plan; Competition; Venture Capital; Biotechnology Industry

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February 2014
Case

BGI: Data-driven Research

By: Willy Shih and Sen Chai

BGI has the largest installed gene-sequencing capacity in the world, and to Zhang Gengyun, general manager of the Life Sciences Division, this represented an opportunity to apply his training as a plant breeder and his early career work as a biochemist to improving... View Details

September 2020 (Revised July 2021)
Case

Moderna (A)

By: Marco Iansiti, Karim R. Lakhani, Hannah Mayer and Kerry Herman

In summer 2020, Stephane Bancel, CEO of biotech firm Moderna, faces several challenges as his company races to develop a vaccine for COVID-19. The case explores how a company builds a digital organization, and leverages artificial intelligence and other digital... View Details

Keywords: COVID-19; Vaccine; Digital Organizations; Organizational Structure; Operations; Management; Health Pandemics; Research and Development; Goals and Objectives

May 2009 (Revised August 2013)
Case

The DiagnoFirst Opportunity

By: Robert C. Pozen and Rukmini Balu

John Mason, a principle at Oldwell Partners, was facing a decision of whether or not to invest in DiagnoFirst, a molecular diagnostics firm. DiagnoFirst's key product was a genetic test that identified a subset of prostate cancer patients with a high risk of clinical... View Details

Keywords: Genetic Engineering; Genetically Modified; Genomics; Venture Capital; Patents; Genetics; Decision Choices and Conditions; Laws and Statutes; Investment; Science-Based Business; Biotechnology Industry

March 2023
Case

Moderna

By: Marco Iansiti, Karim R. Lakhani, Hannah Mayer, Kerry Herman, Allison J. Wigen and Dave Habeeb

This multimedia case follows the story of Moderna and its entry into vaccine development in the wake of the COVID-19 pandemic. In summer 2020, Stephane Bancel, CEO of biotech firm Moderna, faces several challenges as his company races to develop a vaccine for COVID-19.... View Details

Keywords: Health Pandemics; Research and Development; Digital Transformation; Health Testing and Trials; Biotechnology Industry; Pharmaceutical Industry

Web

Faculty & Advisors | MBA

development activities from search and evaluation through definitive document negotiation. He led several completed transactions in the areas of oncology and cell therapy. Andrew held previous roles in translational medicine at Celgene focused on leveraging novel... View Details

01 Jun 2023
News

From Big Pharma to Startup

Hunter Goble (MBA 2022) did not enroll in Harvard Business School with dreams of becoming an entrepreneur. After earning his MBA, Goble intended to return to Eli Lilly to continue to work building brands and launching products. He envisioned himself leading a big,... View Details

Keywords: April White

10 Oct 2024
Blog Post

High-Tech Greenhouse Innovations in The Netherlands

The company plans to pair this with input from consumer panels, distributor and retailer feedback, and most importantly, feedback from growers. Additionally, the company performs DNA sequencing on most of the varieties it tests to build... View Details

Profile

Henry McCance

recent advances in gene sequencing and data mining, he believed he could identify many more genes in a short time with a relatively modest investment. That could lead to the... View Details

Keywords: Venture Capital / Private Equity; Financial Services; Health Care

07 Oct 2014
News

Network Effect

backed if he had chosen the software industry as a career.” Tanzi explained that, owing to recent advances in gene sequencing and data mining, he believed he could identify many more View Details

Keywords: Linda Kush

26 Sep 2024
Blog Post

Syngenta Tomato Vision

growing, high yields) and retailers. It usually takes 8-10 years to develop a completely new tomato variety. Using modern gene mapping technologies to identify traits and accelerate the screening, crossing of existing varieties, and... View Details

01 Jun 2017
News

Drawing on the Crowd for Innovative Problem-Solving

business administration Research at Work: Crowdsourcing Challenge Harvard Business School, in conjunction with its partners, hosted a series of challenges to develop algorithms for faster DNA sequence alignment and to improve analysis of... View Details

10 Jan 2012
First Look

First Look: January 10

AndrewsHarvard Business School Case 812-004 Toward the end of 2010, companies in the gene sequencing industry were pushing aggressive R&D programs to develop technologies and products in the race to... View Details

Keywords: Sean Silverthorne

07 Aug 2000
Research & Ideas

The Business of Biotech

With the sequencing of the human genome running ahead of schedule, the American Stock Exchange's "BTK" biotech index registered an annual increase of 232 percent in February, prompting exuberant headlines ("Move Over,... View Details

Keywords: by Julia Hanna; Biotechnology; Health; Technology

01 Jun 2000
News

The Business of Biotech

With the sequencing of the human genome running ahead of schedule (see sidebar), the American Stock Exchange's "BTK" biotech index registered an annual increase of 232 percent in February, prompting exuberant headlines ("Move Over,... View Details

Keywords: Julia Hanna

26 Jun 2000
Research & Ideas

Presentation Round-Up

noted that telecommunications has traditionally been a very segmented market, but from a macro standpoint it is consolidating as well. The prospective merger between Internet portal Lycos and Spanish Internet service provider Terra Networks, Mulica said, was "a wake-up... View Details

Keywords: by Martha Lagace & Kenneth Liss; Technology; Communications; Telecommunications

03 Mar 2017
News

Big Blue’s Big Bet

of the UNC Lineberger Comprehensive Cancer Center. Besides reading all the medical journals, Watson could inform doctors of when certain drug trials began and when others ended; it could also sequence a genome and find important View Details

Keywords: Paul Kix; illustrations by Dan Page

14 Jul 2009
First Look

First Look: July 14

cancer patients with a high risk of clinical progression and death. DiagnoFirst had applied for patents, in both the U.S. and EU, for the sequence of 40 genes, the new methodology for gene amplification, and... View Details

Keywords: Martha Lagace

13 May 2014
First Look

First Look: May 13

to improving important parts of the world food supply. But his biggest challenge was in scaling up his organization to address the multitude of opportunities he wanted to address. Along with its massive investments in gene View Details

Keywords: Sean Silverthorne

08 May 2012
First Look

First Look: May 8

important later on the experiment (unconscious thought), or to perform the task while believing the experiment had ended (control condition). Afterwards, sequence memory and intrusions of the film were measured. In line with predictions,... View Details

Keywords: Carmen Nobel

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