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- February 2024
- Supplement
Seeds of Innovation: GALY's Quest to Cultivate the Future of Agriculture in the Lab
By: George Serafeim
In 2023, Luciano Bueno, CEO and founder of plant cell culture agriculture company GALY, was considering the best path forward for his company as he planned to pitch Series B investors. GALY, founded in 2019, aimed to produce cotton and other crops from cells grown in... View Details
Keywords: Business Model; Green Technology; Goods and Commodities; Growth and Development Strategy; Science-Based Business; Entrepreneurship; Plant-Based Agribusiness; Business Startups; Decisions; Technological Innovation; Production; Entrepreneurial Finance; Agriculture and Agribusiness Industry; Technology Industry; Boston; Sao Paulo
Serafeim, George. "Seeds of Innovation: GALY's Quest to Cultivate the Future of Agriculture in the Lab." Harvard Business School Multimedia/Video Supplement 124-705, February 2024.
- 2023
- Other Article
The Harvard USPTO Patent Dataset: A Large-Scale, Well-Structured, and Multi-Purpose Corpus of Patent Applications
By: Mirac Suzgun, Luke Melas-Kyriazi, Suproteem K. Sarkar, Scott Duke Kominers and Stuart Shieber
Innovation is a major driver of economic and social development, and information about many kinds of innovation is embedded in semi-structured data from patents and patent applications. Though the impact and novelty of innovations expressed in patent data are difficult... View Details
Keywords: USPTO; Natural Language Processing; Classification; Summarization; Patent Novelty; Patent Trolls; Patent Enforceability; Patents; Innovation and Invention; Intellectual Property; AI and Machine Learning; Analytics and Data Science
Suzgun, Mirac, Luke Melas-Kyriazi, Suproteem K. Sarkar, Scott Duke Kominers, and Stuart Shieber. "The Harvard USPTO Patent Dataset: A Large-Scale, Well-Structured, and Multi-Purpose Corpus of Patent Applications." Conference on Neural Information Processing Systems (NeurIPS), Datasets and Benchmarks Track 36 (2023).
- September 2023 (Revised November 2023)
- Case
Seeds of Innovation: GALY's Quest to Cultivate the Future of Agriculture in the Lab
By: George Serafeim and Michael Norris
In 2023, Luciano Bueno, CEO and founder of plant cell culture agriculture company GALY, was considering the best path forward for his company as he planned to pitch Series B investors. GALY, founded in 2019, aimed to produce cotton and other crops from cells grown in... View Details
Keywords: Business Model; Green Technology; Goods and Commodities; Growth and Development Strategy; Science-Based Business; Entrepreneurship; Plant-Based Agribusiness; Business Startups; Decisions; Technological Innovation; Production; Agriculture and Agribusiness Industry; Technology Industry; Boston; Sao Paulo
Serafeim, George, and Michael Norris. "Seeds of Innovation: GALY's Quest to Cultivate the Future of Agriculture in the Lab." Harvard Business School Case 124-017, September 2023. (Revised November 2023.)
- July 2023 (Revised July 2024)
- Case
Miracle Therapeutics: Negotiating an IP License (A)
By: Satish Tadikonda, Michael Singer, William Marks and Wendi Yajnik
(General Experience Case) Beth Sharp and Jennifer Brilliant founded Miracle Therapeutics based on intellectual property developed by Brilliant and her post-doctoral student, John Supreme, in Brilliant’s lab at Elite University (EU). Miracle will have to obtain a... View Details
Tadikonda, Satish, Michael Singer, William Marks, and Wendi Yajnik. "Miracle Therapeutics: Negotiating an IP License (A)." Harvard Business School Case 824-020, July 2023. (Revised July 2024.)
- April 2023
- Case
Burning the Sails to Save the Ship: The Pilati Family Dilemma
By: Lauren Cohen, Hao Gao, Jiawei Ye and Grace Headinger
Octavian Graf Pilati, rising generation member of an Austrian princely family, prepared to sell the palace his family had held for over three hundred years. In recent years, the Pilati family lands had been leveraged as loan collateral for an international venture that... View Details
Keywords: Family Office; Family; Plant-Based Agribusiness; Agribusiness; Family Business; Property; Identity; Culture; Ethics; Insolvency and Bankruptcy; Governance; Crisis Management; Family and Family Relationships; Agriculture and Agribusiness Industry; Real Estate Industry; Austria
Cohen, Lauren, Hao Gao, Jiawei Ye, and Grace Headinger. "Burning the Sails to Save the Ship: The Pilati Family Dilemma." Harvard Business School Case 223-081, April 2023.
- January 2023
- Case
Crow Holdings Development: Mass Timber Construction
By: John D. Macomber, Robert Hernandez and Kyle MertensMeyer
Jim McCaffery and Cody Armbrister of Crow Holdings Development evaluate the pros and cons of committing to mass timber construction instead of conventional concrete or steel for a new 260,000 SF multi-story office building in Texas. Benefits include substantially... View Details
Keywords: Real Estate Development; Architecture; Air Quality; Health & Wellness; Office Property; Sustainability; Carbon Abatement; Natural Environment; Environmental Accounting; Green Buildings; Design; Construction; Cost vs Benefits; Environmental Sustainability; Construction Industry; Real Estate Industry; Texas
- May 2021
- Case
Inclusive Innovation at Mass General Brigham
By: Katherine Baldiga Coffman and Olivia Hull
Massachusetts General Brigham (MGB) Chief Innovation Officer Christopher Coburn had overseen a period of exciting transformation and growth in healthcare innovation at MGB. In November 2019, the health system was the largest recipient of National Institutes of Health... View Details
Keywords: Inclusion; Innovation; Invention; Gender; Business Startups; Investment Funds; Private Equity; Health Care and Treatment; Innovation Strategy; Technological Innovation; Intellectual Property; Copyright; Patents; Research; Research and Development; Diversification; Technology; Health Industry; Massachusetts; Boston
Coffman, Katherine Baldiga, and Olivia Hull. "Inclusive Innovation at Mass General Brigham." Harvard Business School Case 921-006, May 2021.
- April 2018
- Article
Scope versus Speed: Team Diversity, Leader Experience, and Patenting Outcomes for Firms
By: Prithwiraj Choudhury and Martine R. Haas
How does the organization of patenting activity affect a firm’s patenting outcomes? We investigate how the composition of patenting teams relates to both the scope of their patent applications and the speed of their patent approvals by examining the main effects of... View Details
Keywords: Leader Experience; Micro-foundations Of Innovation; Scope; Speed; Team Diversity; Within-firm Data; Groups and Teams; Diversity; Patents; Leadership; Experience and Expertise; Outcome or Result
Choudhury, Prithwiraj, and Martine R. Haas. "Scope versus Speed: Team Diversity, Leader Experience, and Patenting Outcomes for Firms." Strategic Management Journal 39, no. 4 (April 2018): 977–1002.
- February 2018 (Revised December 2019)
- Case
The Tax Man: Taxes in Private Equity Real Estate
By: Nori Gerardo Lietz, Timothy J. Becker, Ricardo Andrade and Sayiddah F. McCree
In January 2018, Caelan Langan, an associate at KSW Partners LLC (“KSW”), was asked by Katherine Scott, the partner for whom he worked, to recommend a proposed structure to acquire a prominent office building in San Francisco for their most recent fund. Caelan was... View Details
Keywords: Real Estate; Alternative Investment Structures; Property; Acquisition; Private Equity; Investment; Management; Taxation; Policy
Lietz, Nori Gerardo, Timothy J. Becker, Ricardo Andrade, and Sayiddah F. McCree. "The Tax Man: Taxes in Private Equity Real Estate." Harvard Business School Case 218-077, February 2018. (Revised December 2019.)
- April 2017
- Case
The Future of Patent Examination at the USPTO
By: Prithwiraj Choudhury, Tarun Khanna and Sarah Mehta
The U.S. Patent and Trademark Office (USPTO) is the federal government agency responsible for evaluating and granting patents and trademarks. In 2015, the USPTO employed approximately 8,000 patent examiners who granted nearly 300,000 patents to inventors. As of April... View Details
Keywords: Machine Learning; Telework; Collaborating With Unions; Human Resources; Recruitment; Retention; Intellectual Property; Copyright; Patents; Trademarks; Knowledge Sharing; Technology Adoption; Organizational Change and Adaptation; Performance Productivity; Performance Improvement; District of Columbia
Choudhury, Prithwiraj, Tarun Khanna, and Sarah Mehta. "The Future of Patent Examination at the USPTO." Harvard Business School Case 617-027, April 2017.
- March 2017 (Revised December 2018)
- Case
Reawakening the Magic: Bob Iger and the Walt Disney Company
By: David Collis and Ashley Hartman
Mickey Mouse, Snow White, and Buzz Lightyear strolled down Main Street at the grand opening of Hong Kong Disney in the fall of 2005, pausing to snap selfies with enthusiastic children in Mickey Mouse ears. Bob Iger, newly appointed CEO of The Walt Disney Company,... View Details
Keywords: Franchise Management; Brand Management; Culture Change; Business Units; Acquisition Strategy; Technological Change; Disney; ESPN; Cord-cutting; Bob Iger; Strategy; Corporate Strategy; Competitive Advantage; Diversification; Integration; Media; Media and Broadcasting Industry; Entertainment and Recreation Industry; Consumer Products Industry
Collis, David, and Ashley Hartman. "Reawakening the Magic: Bob Iger and the Walt Disney Company." Harvard Business School Case 717-483, March 2017. (Revised December 2018.)
- October 2016 (Revised September 2017)
- Case
The CRISPR-Cas9 Quarrel
By: Richard G. Hamermesh and Matthew G. Preble
In mid-2016, the Broad Institute and the University of California, Berkeley were in the middle of a contentious patent dispute over which entity controlled a breakthrough gene editing technology called CRISPR-Cas9. With CRISPR-Cas9, scientists might soon be able to... View Details
Keywords: CRISPR; Broad Institute; University Of California Berkeley; Intellectual Property; Patents; Law; Lawsuits and Litigation; Science; Genetics; Entrepreneurship; Biotechnology Industry; United States
Hamermesh, Richard G., and Matthew G. Preble. "The CRISPR-Cas9 Quarrel." Harvard Business School Case 817-020, October 2016. (Revised September 2017.)
- June 2016
- Case
The Redevelopment of Palazzo Tornabuoni (A)
By: Sid Yog, Arthur I Segel and Ricardo Andrade
In the spring of 2004, Byrne Murphy and his partners at Fingen Group discussed options to redevelop Palazzo Tornabuoni, an iconic 15th century palace in the heart of Florence, Italy. The possibilities included turning the upper floors into office space, hotel rooms,... View Details
Keywords: Palazzo Tornabuoni; Private Residence Club; Florence; Italy; Timeshare; Fractional Ownership; Property; Real Estate Industry; Italy; Europe
Yog, Sid, Arthur I Segel, and Ricardo Andrade. "The Redevelopment of Palazzo Tornabuoni (A)." Harvard Business School Case 216-069, June 2016.
- June 2016 (Revised March 2017)
- Case
Reworking Office Space: Industry City, Brooklyn
By: Arthur I Segel, Andrew Baum, Nori Gerardo Lietz, Charles F. Wu and Sid Yog
Jamestown is contemplating how to best lease a portion of their new development along the Brooklyn waterfront, Industry City. The 6 million square foot, mixed-use development is meant to accommodate Brooklyn’s growing innovation, creative, and “maker” communities.... View Details
Keywords: WeWork; Office Space; Real Estate; Jamestown; Level39; Shared Office Space; Information Technology; Leasing; Property; Strategy; Real Estate Industry; United States
Segel, Arthur I., Andrew Baum, Nori Gerardo Lietz, Charles F. Wu, and Sid Yog. "Reworking Office Space: Industry City, Brooklyn." Harvard Business School Case 216-075, June 2016. (Revised March 2017.)
- April 2015 (Revised April 2015)
- Case
Yale University Investments Office: February 2015
By: Josh Lerner
David Swensen and the Investments Office staff must decide whether to continue to allocate the bulk of the university's endowment to illiquid investments—hedge funds, private equity, real estate—given the impact of the recent market turmoil. The case explores the risks... View Details
Keywords: Asset Management; Resource Allocation; Investment; Venture Capital; Investment Funds; Property; Private Equity
Lerner, Josh. "Yale University Investments Office: February 2015." Harvard Business School Case 815-124, April 2015. (Revised April 2015.)
- January 2015 (Revised March 2017)
- Case
New Urban Mechanics
By: Mitchell Weiss
Funding to scale Citizens Connect, Boston's 311 app, is both a blessing and a burden and tests two public entrepreneurs. In 2012, the Commonwealth of Massachusetts provides Boston's Mayor's Office of New Urban Mechanics with a grant to scale Citizens Connect across the... View Details
Keywords: Public Entrepreneurship; Civic Technology; Government Innovation; Civic Innovation; Cities; New Urban Mechanics; Thomas. M. Menino; Chris Osgood; Nigel Jacob; Connected Bits; SeeClickFix; Ben Berkowitz; Eric Carlson; Dave Mitchell; Government Technology; Open Innovation; Open Source Software; Citizens Connect; Commonwealth Connect; Entrepreneurship; Innovation and Invention; Innovation Leadership; Innovation and Management; Open Source Distribution; Public Administration Industry; Information Technology Industry; Boston
Weiss, Mitchell. "New Urban Mechanics." Harvard Business School Case 315-075, January 2015. (Revised March 2017.)
- 2018
- Working Paper
Information Provision and Innovation: Natural Experiment of Herbal Patent Prior Art Adoption at the United States and European Patent Offices
By: Prithwiraj Choudhury and Tarun Khanna
We exploit a natural experiment to study how codifying information about prior innovation affects subsequent innovation. A codified database of traditional Indian herbal formulations was adopted by the European Patent Office (EPO) and the U.S. Patent and Trademark... View Details
Keywords: Patents; Plant-Based Agribusiness; Ethnicity; Health Care and Treatment; Pharmaceutical Industry; Agriculture and Agribusiness Industry; China; India
Choudhury, Prithwiraj, and Tarun Khanna. "Information Provision and Innovation: Natural Experiment of Herbal Patent Prior Art Adoption at the United States and European Patent Offices." Harvard Business School Working Paper, No. 14-079, February 2014. (Revised January 2018.)
- October 2011 (Revised March 2013)
- Case
Yale University Investments Office: February 2011
By: Josh Lerner and Ann Leamon
David Swensen and the Investments Office staff must decide whether to continue to allocate the bulk of the university's endowment to illiquid investments—hedge funds, private equity, real estate—given the impact of the recent market turmoil. The case explores the risks... View Details
Keywords: Asset Management; Resource Allocation; Investment; Venture Capital; Investment Funds; Property; Private Equity
Lerner, Josh, and Ann Leamon. "Yale University Investments Office: February 2011." Harvard Business School Case 812-062, October 2011. (Revised March 2013.)
- April 2011
- Teaching Note
Office of Technology Transfer - Shanghai Institutes for Biological Sciences (TN)
By: Willy Shih and Sen Chai
Teaching Note for 611057. View Details
- March 2011 (Revised June 2012)
- Case
Office of Technology Transfer - Shanghai Institutes for Biological Sciences
By: Willy Shih, Sen Chai, Kamen Bliznashki and Courtney Hyland
Gordon Zong is trying to teach Chinese universities and research institutes how to do effective technology transfer and IP licensing, but he is trying to do it in an environment with weak property rights and an underdeveloped support infrastructure. As the managing... View Details
Keywords: Multinational Firms and Management; Patents; Knowledge Management; Law Enforcement; Business and Government Relations; Research and Development; Biotechnology Industry; Pharmaceutical Industry; China
Shih, Willy, Sen Chai, Kamen Bliznashki, and Courtney Hyland. "Office of Technology Transfer - Shanghai Institutes for Biological Sciences." Harvard Business School Case 611-057, March 2011. (Revised June 2012.)