Publications

10 Jul 2014
News

How Harvard Medical School Uses Open Innovation To Solve World-Class Scientific Problems

October 2013 (Revised January 2014)
Supplement

Fred Khosravi and AccessClosure (B)

By: Richard G. Hamermesh and Lauren Barley

It was January 2013, and Fred Khosravi, chairman of the board of AccessClosure Inc., wondered what the new year had in store for him and AccessClosure, the company he founded in late 2002. Khosravi was cautiously optimistic—the Mountain View, California-based medical... View Details

Keywords: Medical Devices; Vascular Closure Device; Patent Litigation; Patenting; Biomedical Research; Biotechnology; Biotech; Technological Innovation; Patents; Health Care and Treatment; Biotechnology Industry; United States; California

March 2006
Teaching Note

Stan Lapidus: Profile of a Medical Entrepreneur (TN)

By: Robert F. Higgins, Richard G. Hamermesh and Erin Seefeld

Teaching Note to (805-087). View Details

Keywords: Personal Development and Career; Entrepreneurship; Business Startups; Biotechnology Industry; Biotechnology Industry

January 2014
Supplement

Fred Khosravi and AccessClosure (C)

By: Richard Hamermesh and Lauren Barley

On September 11, 2013, the three-judge panel of the U.S. Court of Appeals for the Federal Circuit denied St. Jude's request to rehear an appeal on the "double patenting" ruling for the '439 patent. Further, it removed the injunction threat that was hanging over the... View Details

Keywords: Medical Devices; Vascular Closure Device; Patent Litigation; Patenting; Biomedical Research; Biotechnology; Biotech; Technological Innovation; Patents; Health Care and Treatment; Biotechnology Industry; United States

January 2014 (Revised June 2015)
Teaching Note

Amgen Inc: Pursuing Innovation and Imitation? (A), (B)

By: Ian Mackenzie

Keywords: Strategic Change; Biosimilars; Medical Biotechnology; Emerging Markets; Industry Structure; Uncertainty; Strategy Development; Implementation; Corporate Strategy; Biotechnology Industry; Biotechnology Industry; United States

15 Apr 2014
News

Bertarelli Foundation Gift Names Deans' Health & Life Sciences Challenge Prize

Life Sciences Challenge, launched in 2012 and chaired by Dean Nohria and Dr. Jeffrey S. Flier, dean of the Faculty of Medicine, Harvard Medical School. In recognition of the donor's generosity, the Deans' Challenge prize will be named the... View Details

Keywords: i-Lab; Harvard Medical School; Scientific Research and Development Services

February 2006 (Revised August 2006)
Case

deCODE Genetics: Hunting for Genes to Develop Drugs

By: Debora L. Spar

In 1996, Kari Stefansson launched a new kind of biotechnology company and a whole new way of attacking diseases. Based in Iceland, his firm, deCODE Genetics, plans to identify the individual genetic markers that lead to society's most prevalent diseases. To do so, it... View Details

Keywords: Information; Innovation Strategy; Genetics; Ethics; Health Disorders; Biotechnology Industry; Iceland

January 2011 (Revised January 2012)
Supplement

The Case of the Unidentified Healthcare Companies2010 (CW)

By: Richard M.J. Bohmer, Ethan S Bernstein, Margarita Krivitski and Srinidhi Reddy

This case presents financial statements and selected rations for 14 unidentified healthcare organizations and asks that each set of financial information be matched with one of the following healthcare companies: a biotechnology firm, a community nursing company, a... View Details

Keywords: Financial Statements; Financial Management; Health Care and Treatment; Biotechnology Industry; Biotechnology Industry

January 2011 (Revised January 2012)
Case

The Case of the Unidentified Healthcare Companies2010

By: Richard Bohmer, Ethan Bernstein, Margarita Krivitski and Srinidhi Reddy

This case presents financial statements and selected ratios for 14 unidentified healthcare organizations and asks that each set of financial information be matched with one of the following healthcare companies: a biotechnology firm, a community nursing company, a... View Details

Keywords: Financial Reporting; Financial Statements; Health Care and Treatment; Health Industry

13 Jan 2003
Research & Ideas

Making Biotech Work as a Business

for example, was a banner year for bad news, with thirty late-stage clinical failures of biotech drugs, he said. The online magazine Signals, which is published by Recombinant Capital, a consulting firm that works on biotechnology... View Details

Keywords: by Martha Lagace; Biotechnology; Biotechnology; Biotechnology

Gary P. Pisano

Gary Pisano is the Harry E. Figgie, Jr. Professor of Business Administration at the Harvard Business School where he has been on the faculty since 1988. From 2018-2023, Pisano was Harvard Business School’s Senior Associate Dean for Faculty Promotion and... View Details

Keywords: biotechnology; biotechnology; biotechnology; biotechnology; biotechnology

July–August 2021
Article

Lowering the Bar? External Conditions, Opportunity Costs, and High-Tech Startup Outcomes

By: Annamaria Conti and Maria P. Roche

We assess the heterogeneous impact of economic downturns on individuals’ decisions to bring high-technology ideas to the market in the form of new ventures. We thereby examine how worsening labor market conditions influence individuals’ opportunity costs of starting... View Details

Keywords: Necessity Entrepreneurship; Economic Conditions; Recessions; High-tech Startups; Opportunity Costs; Entrepreneurship; Economic Slowdown and Stagnation; Business Startups; Information Technology; Performance; Labor

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Person Page

Press / Media

By: Gary P. Pisano

Thought Leader: Gary Pisano

by Amy Bernstein, strategy+business, Summer 2007

A leading student of the biotech business describes the problems holding the industry back, and how it can overcome... View Details

09 Oct 2020
Blog Post

4 Things To Know About the MS/MBA Biotech

myself, did come from a biotechnology company, but there were also people from life sciences consulting firms, research laboratories, medical device companies and larger pharmaceutical companies. This... View Details

June 2005 (Revised July 2006)
Background Note

Note on the Convergence Between Genomics & Information Technology

By: David B. Yoffie, Dharmesh M Mehta and Rachel Sha

Focuses on the convergence between the genomics and semiconductor industries, in particular organ printing, DNA computing, biomolecular sensory networks, and DNA microarrays. Explains what this newly converged world looks like based on current research and findings in... View Details

Keywords: Genetics; Information Technology; Business Model; Disruptive Innovation; Biotechnology Industry; Biotechnology Industry; Biotechnology Industry; Biotechnology Industry

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September 2014
Case

Pfizer's Centers for Therapeutic Innovation (CTI)

By: Gary Pisano, James Weber and Kait Szydlowski

In 2010, Pfizer established four small research units in New York, Boston, San Francisco, and San Diego located close to several premier Academic Medical Centers (AMCs), or hospitals with adjoining medical schools. The goal of these units was to redesign collaboration... View Details

Keywords: Drug Development; Academic Collaboration; Research And Development; Innovation; Translational Research; Management; Operations; Problems and Challenges; Research; Science; Information Technology; Strategy; Biotechnology Industry; Biotechnology Industry; North and Central America; Europe; Asia

April 1993 (Revised October 1995)
Case

ALZA and Bio-Electro Systems (A): Technological and Financial Innovation

By: Josh Lerner and Peter Tufano

To develop the next generation of risky products, ALZA, a mature and profitable biotechnology firm specializing in drug delivery systems, must raise $40 million. Organizational constraints and competitive concerns demand that the work be done inside the firm. However,... View Details

Keywords: Risk and Uncertainty; Technological Innovation; Business Subsidiaries; Decision Choices and Conditions; Corporate Finance; Biotechnology Industry; Biotechnology Industry