Publications

March 1996 (Revised April 1996)
Case

State Street Bank and Trust Company: New Product Development

By: Gary P. Pisano and Maryam Golnaraghi

Portrays the dilemma faced by Marsh Carter, CEO and chairman of the board of State Street Bank, in May 1995. For the past decade, the bank earned continually expanding earnings through its rapidly growing custody business. Now, as that business matures and custodial... View Details

Keywords: Product Development; Finance; Problems and Challenges; Management Teams; Organizational Change and Adaptation; Change Management; Strategy; Banking Industry

Article

What Evolution Can Teach Us About Innovation

By: Noubar Afeyan and Gary P. Pisano

Many people believe that the process for achieving breakthrough innovations is chaotic, random, and unmanageable. But that view is flawed, the authors argue. Breakthroughs can be systematically generated using a process modeled on the principles that drive evolution in... View Details

Keywords: Breakthrough Innovation; Variance Generation; Selection Pressure; Emergent Discovery; Innovation and Invention; Value Creation; Innovation Leadership

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September 2018
Article

Knowledge Integrators and the Survival of Manufacturing Clusters

By: Giulio Buciuni and Gary P. Pisano

Over the past two decades, the greater prevalence of global supply chains has had contrasting effects on Western manufacturing clusters. While some of them dwindled, others proved resilient. Contributing to the recent literature on co-located clusters and clusters'... View Details

Keywords: Production; Industry Clusters; Knowledge Use and Leverage; Strategy; Competition

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March 2000
Case

Heartport, Inc.

By: Gary P. Pisano and Shoshana Dobrow

Heartport, an entrepreneurial medical device maker, has introduced several innovative systems for conducting less-invasive cardiac surgery. Despite initially high expectations, the company has struggled to get its technology adopted by cardiac surgeons. The company's... View Details

Keywords: History; Product Positioning; Knowledge Acquisition; Corporate Entrepreneurship; Technology Adoption; Health Care and Treatment

March 2011
Case

MorphoSys AG: The Evolution of a Biotechnology Business Model

By: Gary P. Pisano, Ryan Johnson and Carin-Isabel Knoop

In the biotech world, the 18-year-old Munich-based company MorphoSys was a rarity: it was profitable. The company achieved this profitability not by developing and selling its own drugs, but by licensing access to its proprietary library of human antibodies. Recently,... View Details

Keywords: Business Model; Profit; Intellectual Property; Rights; Risk Management; Digital Platforms; Product Development; Business and Shareholder Relations; Vertical Integration; Biotechnology Industry; Munich

24 Sep 2013
First Look

First Look: September 24

invest in platform quality in open-source and proprietary two-sided platforms. Open platforms have open access, and developers invest to improve the platform. Proprietary platforms have closed access, and investment is done by the... View Details

Keywords: Sean Silverthorne

August 2007 (Revised June 2010)
Case

JetBlue Airways: Valentine's Day 2007 (A)

By: Robert S. Huckman, Gary P. Pisano and Virginia Fuller

Describes an operational crisis for JetBlue Airways during an ice storm in the eastern United States in February 2007 and chronicles the airline's immediate response. Provides detail concerning the history of the airline from its founding in 1999 through the February... View Details

Keywords: Customer Relationship Management; Crisis Management; Growth Management; Management Teams; Service Delivery; Air Transportation Industry; Eastern United States

11 May 2010
First Look

First Look: May 11

Amyris Biotechnologies: Commercializing Biofuel Gary P. Pisano and Alison Berkley WagonfeldHarvard Business School Case 610-031 In 2009, Amyris Biotechnologies was building a plant in Brazil that used... View Details

Keywords: Martha Lagace

Article

The Evolution of Science-Based Business: Innovating How We Innovate

By: Gary P. Pisano

Science has long been connected to innovation and to business. As early as the late 19th century, chemical companies, realizing the commercial potential of science, created the first industrial research laboratories. During much of the 20th century, large-scale... View Details

Keywords: Entrepreneurship; Governance; Innovation and Management; Risk Management; Research and Development; Science-Based Business; Commercialization

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18 Mar 2008
First Look

First Look: March 18, 2008

this time. Toward a Theory of Behavioral Operations Authors:Francesca Gino and Gary P. Pisano Publication:Manufacturing and Service Operations Management (forthcoming) Abstract Human beings are critical to... View Details

Keywords: Martha Lagace

March 2023
Case

Azenta Life Sciences: The Road to Transformation

By: Gary P. Pisano and Catherine Piner

When the Board brought Steve Schwartz in as President of Brooks Automation in 2010, they gave him a clear mission: strengthen the company’s core semiconductor equipment business and find a new industry to enter. Over the course of the next decade, Schwartz and the... View Details

Keywords: Transformation; Business and Shareholder Relations; Market Entry and Exit; Organizational Change and Adaptation; Segmentation; Technology Industry

16 Jun 2015
First Look

First Look: June 16, 2015

Business Review You Need an Innovation Strategy By: Pisano, Gary P. Abstract—Why is it so hard to build and maintain the capacity to innovate? The reason is not simply a failure to execute but a failure to articulate an innovation... View Details

Keywords: Sean Silverthorne

Article

Variety of Innovation in Global Value Chains

By: Giulio Buciuni and Gary P. Pisano

This article analyzes how the geography and organization of pre- and production stages in Global Value Chains (GVC) contribute to lead firms' innovation development. A novel approach in GVC studies is introduced based on transaction cost economics (TCE) and the... View Details

Keywords: GVC; Global Value Chains; Manufacturing; Production; Global Range; Innovation and Invention

October 2018
Article

A Theory of Intergenerational Mobility

By: Gary Becker, Scott Duke Kominers, Kevin Murphy and Jorg L. Spenkuch

We develop a model of intergenerational resource transmission that emphasizes the link between cross-sectional inequality and intergenerational mobility. By drawing on first principles of human capital theory, we derive several novel results. In particular, we show... View Details

Keywords: Intergenerational Mobility; Inequality; Complementarities; Equality and Inequality; Human Capital; Income; Family and Family Relationships

September 2002 (Revised April 2006)
Case

Istituto Clinico Humanitas (A)

By: Richard M.J. Bohmer, Gary P. Pisano and Ning Tang

Istituto Clinico Humanitas is a newly built private hospital, south of Milan, Italy, that has attained unusual profitability while treating public system patients. The hospital was built and is managed by Techosp, a subsidiary of Techint, a global engineering and... View Details

Keywords: Health Care and Treatment; Management Analysis, Tools, and Techniques; Management Systems; Infrastructure; Managerial Roles; Integration; Performance; Health Industry; Milan

20 Apr 2010
First Look

First Look: April 20

Business: Innovating How We Innovate Author: Gary P. Pisano Publication: Special Issue on Management Innovation-Essays in the Spirit of Alfred D. ChandlerIndustrial and Corporate Change 19, no. 2 (2010):... View Details

Keywords: Martha Lagace

31 Jul 2018
First Look

New Research and Ideas, July 31, 2018

of Manufacturing Clusters By: Buciuni, Giulio, and Gary P. Pisano Abstract—Over the past two decades, the greater prevalence of global supply chains has had contrasting effects on Western manufacturing... View Details

Keywords: Dina Gerdeman

2015
Working Paper

A Theory of Intergenerational Mobility

By: Gary Becker, Scott Duke Kominers, Kevin Murphy and Jorg L. Spenkuch

We develop a model of intergenerational resource transmission that emphasizes the link between cross-sectional inequality and intergenerational mobility. By drawing on first principles of human capital theory, we derive several novel results. In particular, we show... View Details

Keywords: Intergenerational Mobility; Inequality; Complementarities; Human Capital; Equality and Inequality; Income; Family and Family Relationships