Publications

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July 2011 (Revised January 2013)
Case

Digital Microscopy Is Making Me Crazy!

By: Willy Shih

For Carl Zeiss Microimaging, modular hardware and software enabled customers to tailor Zeiss's broad range of microscopy systems hardware and software to meet a wide range of needs from basic scientific research in the biological and medical sciences to clinical... View Details

Keywords: Information Infrastructure; Applications and Software; Corporate Strategy; Disruptive Innovation; Science-Based Business; Management Analysis, Tools, and Techniques; Business Conglomerates; Digital Platforms; Opportunities; Medical Devices and Supplies Industry; Computer Industry

October 2012
Case

Designing a Culture of Collaboration at Lake Nona Medical City

By: Amy C. Edmondson, Sydney Ribot and Tiona Zuzul

Describes Lake Nona, a 7,000-acre residential and research cluster in central Florida, and its process and innovation culture, and Lake Nona Institute, the organization behind the planning and governance of this new eco-friendly community. Emphasis is placed on the... View Details

Keywords: Collaboration; Innovation; Health Care; Real Estate; Entrepreneurship; Collaborative Innovation and Invention; Governance; Real Estate Industry; Florida

September 2017
Case

Sensing (and Monetizing) Happiness at Hitachi

By: Ethan Bernstein and Stephanie Marton

Inspired by research linking happiness and productivity, Hitachi had invested in developing new “people analytics” technologies to help companies increase employee happiness. Hitachi had begun manufacturing high-tech badges that quantify a wearer’s activity patterns.... View Details

Keywords: People Analytics; Japan; Sociometers; Wearables; Interpersonal Communication; Human Resources; Happiness; Technology Industry; Japan

2012
Book

Producing Prosperity: Why America Needs a Manufacturing Renaissance

By: Gary P. Pisano and Willy Shih

For years—even decades—in response to intensifying global competition, American companies decided to outsource their manufacturing operations in order to reduce costs. But we are now seeing the alarming long-term effect of those choices: in many cases, once... View Details

Keywords: Job Cuts and Outsourcing; Production; Competitive Advantage; Transformation; Innovation and Invention; Manufacturing Industry; United States

2024
Working Paper

Bootstrap Diagnostics for Irregular Estimators

By: Isaiah Andrews and Jesse M. Shapiro

Empirical researchers frequently rely on normal approximations in order to summarize and communicate uncertainty about their findings to their scientific audience. When such approximations are unreliable, they can lead the audience to make misguided decisions. We... View Details

Keywords: Mathematical Methods; Decision Choices and Conditions

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March 1, 2022
Article

Widespread Use of National Academies Consensus Reports by the American Public

By: Diana Hicks, Matteo Zullo, Ameet Doshi and Omar Isaac Asensio

In seeking to understand how to protect the public information sphere from corruption, researchers understandably focus on dysfunction. However, parts of the public information ecosystem function very well, and understanding this as well will help in protecting and... View Details

Keywords: Reports; Surveys; AI and Machine Learning; Knowledge Dissemination; Knowledge Use and Leverage

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September 2014
Article

Pollution and Skin: From Epidemiological and Mechanistic Studies to Clinical Implications

By: Jean Krutmann, Wei Liu, Li Li, Xiaochuan Pan, Martha Crawford, Gabrielle Sore and Sophie Seite

In recent years, the health effects associated with air pollution have been intensively studied. Most studies focus on air pollution effects on the lung and the cardiovascular system. More recently, however, epidemiological and mechanistic studies suggest that air... View Details

Keywords: Pollutants; Health Disorders; Medical Specialties

2010
Working Paper

A New Paradigm of Individual, Group and Organizational Performance

By: Werner Erhard, Michael C. Jensen and The Barbados Group

"The committee is therefore unable to draw conclusions, based on scientific evidence, on what does or does not work to enhance organizational performance" —Committee on Techniques for the Enhancement of Human Performance of the U.S. National Research Council Commission... View Details

Keywords: Organizations; Performance Improvement; Research; Opportunities

SSRN

July–August 2008
Article

Interview with a Quality Leader: Regina E. Herzlinger on Consumer-Driven Healthcare

By: Regina E. Herzlinger

Regina E. Herzlinger is the Nancy R. McPherson Professor of Business Administration Chair at the Harvard Business School, Cambridge, MA. She received her bachelor's degree from MIT and her doctorate from the Harvard Business School The first woman to be tenured and... View Details

Keywords: Consumer-driven Health Care; Health Care and Treatment; Health Industry

March 2008
Case

Novartis AG: Science-Based Business

By: H. Kent Bowen and Courtney Purrington

Novartis is a science-based drug company, which has important implications for its business strategy. It is one of the largest pharmaceutical companies in the world with over $38B in sales in 2007. Pharmaceuticals account for slightly over $24B of that total. In 2007,... View Details

Keywords: Innovation and Invention; Resource Allocation; Product Development; Partners and Partnerships; Research and Development; Science-Based Business; Pharmaceutical Industry

02 Jun 2022
Research & Ideas

Blissful Thinking: When It Comes to Finding Happiness, 'Your Dreams Are Liars'

and a former professional French-horn player, Brooks came to the subject of happiness by way of art. His early research focused on why people produce and consume art and beauty as well as the motives behind human generosity. He discovered... View Details

Keywords: by Dan Morrell

06 Jun 2016
Research & Ideas

Skills and Behaviors that Make Entrepreneurs Successful

financed them—declared such brick-and-mortar businesses were dinosaurs on their way to extinction. The success of Bluemercury proved the critics wrong. “We’ve always had a hard time being able to identify the skills and behaviors of entrepreneurial leaders” Despite... View Details

Keywords: by HBS Working Knowledge

November 2014
Teaching Note

Claritas Genomics

By: Robert F. Higgins and Matthew G. Preble

Dr. Patrice Milos is the first CEO of Claritas Genomics (Claritas) and she faces a number of challenges in scaling the young company. Claritas was formed around a lab spun out from Boston Children's Hospital (BCH) which had performed genomic tests for the hospital. Now... View Details

Keywords: Healthcare; Healthcare Startups; Genetic Testing; Genetics Diagnostics; Spinning Out Hospital Services; Spin-out; Health Care and Treatment; Genetics; Entrepreneurship; Biotechnology Industry; Health Industry; United States

February 2016
Article

Bridging Science and Technology Through Academic-Industry Partnerships

By: Sen Chai and Willy C. Shih

Partnerships that foster the translation of scientific advances emerging from academic research organizations into commercialized products at private firms are a policy tool that has attracted increased interest. This paper examines empirical data from the Danish... View Details

Keywords: Economic Development; Technological Change; Government Policy; Technological Innovation; Research and Development; Information Technology; Policy; Technology Industry; Denmark

May 2006
Case

A123Systems

By: H. Kent Bowen, Kenneth P Morse and Douglass Cannon

A 123Systems was a young company that was founded on basic materials science research at the Massachusetts Institute of Technology. A co-founder of the company, Yet-Ming Chiang, was a full professor at MIT and served as scientific adviser. Intellectual property based... View Details

Keywords: Intellectual Property; Business Startups; Research and Development; Commercialization; Technological Innovation; Science-Based Business; Product Development; Battery Industry; Electronics Industry; Massachusetts

2019
Working Paper

Breaking and Reconfiguring the Boundaries Between Domain Experts and Crowds to Solve Complex R&D Problems through Partial Decomposition

By: Hila Lifshitz - Assaf and Zoe Szajnfarber

The need for domain experts is all but universally assumed when organizing for scientific and technological innovation. In contrast, we are witnessing a burgeoning of citizen science, crowdsourcing, and other “open” methods based on the opposite assumption that crowds... View Details

Keywords: Innovation; Problem Solving; Expertise; Crowdsourcing; Nasa; Experience and Expertise; Collaborative Innovation and Invention; Research and Development