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Show Results For
- All HBS Web
(619)
- People (1)
- News (203)
- Research (299)
- Events (3)
- Multimedia (10)
- Faculty Publications (172)
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- February 2009
- Case
Avid Radiopharmaceuticals: The Venture Debt Question
By: Matthew Rhodes-Kropf and Ann Leamon
The CEO of a promising biotech company must decide how to respond to the macro-economic slump of late 2008. He had planned to pursue an aggressive schedule, moving the firm's Alzheimer's and Parkinson's disease imaging compounds through clinical trials and into the... View Details
Keywords: Financial Crisis; Entrepreneurship; Borrowing and Debt; Venture Capital; Financial Management; Investment; Health Testing and Trials; Expansion; Biotechnology Industry; Pharmaceutical Industry
Rhodes-Kropf, Matthew, and Ann Leamon. "Avid Radiopharmaceuticals: The Venture Debt Question." Harvard Business School Case 809-086, February 2009.
- Research Summary
Overview
My research seeks to understand and improve service integration across specialized professions and organizations. A critical idea driving my research is that work is becoming more dynamic, complex and interconnected, particularly for work that addresses difficult... View Details
- March 2010 (Revised October 2011)
- Case
Highland District County Hospital: Gastroenterology Care in Sweden
By: Michael E. Porter, Jennifer F Baron and Martin Rejler
Sweden's Highland District County Hospital, similar to a community hospital in the US, undertook a major restructuring to integrate care delivery for medical conditions served by the Department of Medicine. Each subspecialty within the Department would form a single,... View Details
Porter, Michael E., Jennifer F Baron, and Martin Rejler. "Highland District County Hospital: Gastroenterology Care in Sweden." Harvard Business School Case 710-469, March 2010. (Revised October 2011.)
- February 2020 (Revised January 2024)
- Case
Wellthy: The Economics of Caring
By: Brian L. Trelstad and Joseph B. Fuller
In 2014, Lindsay Jurist-Rosner (MBA ’09) founded Wellthy, a B2C business that coordinates care for working professionals seeking help to support loved ones with chronic diseases or aging parents. With personal experience as a young professional providing care for her... View Details
Keywords: B2B Vs. B2C; Future Of Work; Health; Social Entrepreneurship; Growth and Development Strategy; Health Industry; United States
Trelstad, Brian L., and Joseph B. Fuller. "Wellthy: The Economics of Caring." Harvard Business School Case 320-028, February 2020. (Revised January 2024.)
- November 2005 (Revised December 2005)
- Case
County Department of Public Health: Organizing for Emergency Preparedness and Response
By: Lynda M. Applegate, Ajay Vinze and Minu Ipe
The anthrax attacks of 2001 exposed serious inadequacies in the response of the U.S. public health system to meet such grave threats. The public health infrastructure required rebuilding to respond to any type of large-scale health emergency. The Public Health... View Details
Keywords: Information Technology; Change Management; Crisis Management; Health Care and Treatment; Infrastructure; Public Administration Industry; Health Industry; United States
Applegate, Lynda M., Ajay Vinze, and Minu Ipe. "County Department of Public Health: Organizing for Emergency Preparedness and Response." Harvard Business School Case 806-089, November 2005. (Revised December 2005.)
- September 2002 (Revised August 2003)
- Case
Genzyme's Gaucher Initiative: Global Risk and Responsibility
By: Christopher A. Bartlett and Andrew N. McLean
In Egypt, Genzyme's humanitarian commitment to treat all sufferers of the rare Gaucher disease worldwide first confronts its commercial imperative to recoup the huge investment required to bring the drug Cerezyme to market. Here Tomye Tierney must decide how to balance... View Details
Keywords: Moral Sensibility; Investment; Emerging Markets; Negotiation; Corporate Social Responsibility and Impact; Business and Government Relations; Sales; Commercialization; Expansion; Value Creation
Bartlett, Christopher A., and Andrew N. McLean. "Genzyme's Gaucher Initiative: Global Risk and Responsibility." Harvard Business School Case 303-048, September 2002. (Revised August 2003.)
- 2023
- Article
Building the Business Case for an Inclusive Approach to Digital Health Measurement with a Web App (Market Opportunity Calculator): Instrument Development Study
By: Mitchell Tang, Yashoda Sharma, Jennifer C. Goldsack and Ariel Dora Stern
Background: The use of digital health measurement tools has grown substantially in recent years. However, there are concerns that the promised benefits from these products will not be shared equitably. Underserved populations, such as those with lower education and... View Details
Keywords: Demographics; Product Development; Health Care and Treatment; Medical Devices and Supplies Industry
Tang, Mitchell, Yashoda Sharma, Jennifer C. Goldsack, and Ariel Dora Stern. "Building the Business Case for an Inclusive Approach to Digital Health Measurement with a Web App (Market Opportunity Calculator): Instrument Development Study." JMIR Formative Research 7 (2023).
- December 2009
- Article
From a Declaration of Values to the Creation of Value in Global Health
By: Jim Yong Kim, Joseph Rhatigan, Sachin H. Jain and Michael E. Porter
To make best use of the new dollars available for the treatment of disease in resource poor settings, global health practice requires a strategic approach that emphasizes value for patients, defined as health outcomes per dollar spent. Practitioners and global health... View Details
- September–October 2020
- Article
The Past, Present, and (Near) Future of Gene Therapy and Gene Editing
By: Julia Pian, Amitabh Chandra and Ariel Dora Stern
Emerging gene therapy and gene-editing technologies will have a growing impact on patient lives and health-care delivery. We analyzed a decade of data on clinical trials and venture capital investments to understand the likely trajectory of genetically focused... View Details
Keywords: Gene Therapy; Gene Editing; Impact; Health Care and Treatment; Technological Innovation; Health Testing and Trials; Venture Capital; Change
Pian, Julia, Amitabh Chandra, and Ariel Dora Stern. "The Past, Present, and (Near) Future of Gene Therapy and Gene Editing." NEJM Catalyst Innovations in Care Delivery 1, no. 5 (September–October 2020).
- July 2019
- Article
The Impact of Price Regulation on the Availability of New Drugs in Germany
By: Ariel Dora Stern, Felicitas Pietrulla, Annika Herr, Aaron S. Kesselheim and Ameet Sarpatwari
The 2011 German Pharmaceutical Market Restructuring Act (“AMNOG”) subjected branded, non-rare disease drugs to price regulation based on an assessment of their clinical benefit. Assessment outcomes range from “major added benefit” to “less benefit than the appropriate... View Details
Keywords: Regulation; Pharmaceuticals; Healthcare; Health Care and Treatment; Price; Governing Rules, Regulations, and Reforms; Pharmaceutical Industry; Germany
Stern, Ariel Dora, Felicitas Pietrulla, Annika Herr, Aaron S. Kesselheim, and Ameet Sarpatwari. "The Impact of Price Regulation on the Availability of New Drugs in Germany." Health Affairs 38, no. 7 (July 2019): 1182–1187.
- Article
Fast Generalized Subset Scan for Anomalous Pattern Detection
By: Edward McFowland III, Skyler Speakman and Daniel B. Neill
We propose Fast Generalized Subset Scan (FGSS), a new method for detecting anomalous patterns in general categorical data sets. We frame the pattern detection problem as a search over subsets of data records and attributes, maximizing a nonparametric scan statistic... View Details
Keywords: Pattern Detection; Anomaly Detection; Knowledge Discovery; Bayesian Networks; Scan Statistics; Analytics and Data Science
McFowland III, Edward, Skyler Speakman, and Daniel B. Neill. "Fast Generalized Subset Scan for Anomalous Pattern Detection." Art. 12. Journal of Machine Learning Research 14 (2013): 1533–1561.
- April 2011
- Article
Improving Cancer Care Through Public Reporting Of Meaningful Quality Measures
By: Tracy E. Spinks, Ronald Walters, Thomas W. Feeley, Heidi Wied Albright, Victoria S. Jordan, John Bingham and Thomas W. Burke
Historically, quality measures for cancer have followed a different route than overall quality measures in the health care system. Many specialized cancer treatment centers were exempt from standard reporting on quality measures because of the complexity of cancer.... View Details
Keywords: Cancer; Quality Metrics; Public Reporting; Affordable Care Act; Quality; Health; Health Industry; North and Central America
Spinks, Tracy E., Ronald Walters, Thomas W. Feeley, Heidi Wied Albright, Victoria S. Jordan, John Bingham, and Thomas W. Burke. "Improving Cancer Care Through Public Reporting Of Meaningful Quality Measures." Health Affairs 30, no. 4 (April 2011): 664–672. (doi: 10.1377/hlthaff.2011.0089.)
- 2022
- Working Paper
TalkToModel: Explaining Machine Learning Models with Interactive Natural Language Conversations
By: Dylan Slack, Satyapriya Krishna, Himabindu Lakkaraju and Sameer Singh
Practitioners increasingly use machine learning (ML) models, yet they have become more complex and harder to understand. To address this issue, researchers have proposed techniques to explain model predictions. However, practitioners struggle to use explainability... View Details
Slack, Dylan, Satyapriya Krishna, Himabindu Lakkaraju, and Sameer Singh. "TalkToModel: Explaining Machine Learning Models with Interactive Natural Language Conversations." Working Paper, 2022.
- August 2018
- Article
The Effect of Graphic Warnings on Sugary-Drink Purchasing
By: Grant Donnelly, Laura Y. Zatz, Daniel Svirsky and Leslie John
Governments have proposed text warning labels to decrease consumption of sugary drinks – a contributor to chronic diseases like diabetes. However, they may be less effective than more evocative, graphic warning labels. We field-tested the effectiveness of graphic... View Details
Keywords: Policy Making; Preferences; Food; Health; Policy; Information; Labels; Consumer Behavior; Decision Making; Performance Effectiveness
Donnelly, Grant, Laura Y. Zatz, Daniel Svirsky, and Leslie John. "The Effect of Graphic Warnings on Sugary-Drink Purchasing." Psychological Science 29, no. 8 (August 2018): 1321–1333.
- December 2012 (Revised November 2014)
- Case
W.R. Grace & Co.: Dealing with Asbestos Torts
By: Stuart C. Gilson and Sarah L. Abbott
A manufacturer of building products and specialty chemicals, W. R. Grace & Co. filed for Chapter 11 bankruptcy in 2001 in response to a flood of lawsuits alleging that its products contained asbestos, and had caused hundreds of thousands of people to contract... View Details
Keywords: Bankruptcy Reorganization; Business Failures; Environmental Regulations; Class Action Lawsuits; Natural Environment; Valuation; Health Disorders; Capital Structure; Restructuring; Lawsuits and Litigation; Chemicals; Crisis Management; Insolvency and Bankruptcy; Legal Liability; Construction Industry; Chemical Industry; United States
Gilson, Stuart C., and Sarah L. Abbott. "W.R. Grace & Co.: Dealing with Asbestos Torts." Harvard Business School Case 213-046, December 2012. (Revised November 2014.)
- July 2022
- Teaching Plan
Wellthy: The Economics of Caring
By: Brian Trelstad
Teaching Plan for HBS Case No. 320-028. In 2014, Lindsay Jurist-Rosner (MBA ’09) founded Wellthy, a B2C business that coordinates care for working professionals seeking help to support loved ones with chronic diseases or aging parents. With personal experience as a... View Details
- September 2020
- Case
Enabling Teamwork at the Cleveland Clinic
By: Amy C. Edmondson and Michaela J. Kerrissey
This case examines efforts to foster teamwork within and across work units in the Cleveland Clinic, a large, distributed healthcare delivery organization. With a long history of valuing teamwork since its founding in 1921, the Clinic had taken dramatic steps to further... View Details
Keywords: Teamwork; Teaming; Health Care; Health Care and Treatment; Groups and Teams; Health Industry; United States
Edmondson, Amy C., and Michaela J. Kerrissey. "Enabling Teamwork at the Cleveland Clinic." Harvard Business School Case 621-040, September 2020.
- November 2009 (Revised January 2011)
- Case
International AIDS Vaccine Initiative
By: Allen S. Grossman and Cathy Ross
Dedicated to accelerating the development of a safe, effective, accessible, preventive HIV vaccine, the International AIDS Vaccine Initiative (IAVI) pioneered ways of addressing the inadequate incentive structures that prevented progress toward vaccines for AIDS and... View Details
Keywords: Developing Countries and Economies; Globalized Firms and Management; Health Care and Treatment; Health Disorders; Business and Government Relations; Partners and Partnerships; Research and Development; Social Enterprise; Health Industry
Grossman, Allen S., and Cathy Ross. "International AIDS Vaccine Initiative." Harvard Business School Case 310-015, November 2009. (Revised January 2011.)
- December 2006 (Revised August 2008)
- Case
Pervasis Therapeutics, Inc.
By: Robert F. Higgins and Virginia Fuller
In May 2005, Steve Bollinger was about to become president and chief operating officer of Pervasis Therapeutics, a small cell therapy start-up in Cambridge, Mass. If proven successful, Pervasis' product, Vascugel, could change the way vascular disease is treated and... View Details
Keywords: Business Startups; Venture Capital; Financial Strategy; Governing Rules, Regulations, and Reforms; Health Care and Treatment; Health Testing and Trials; Health Industry; Cambridge
Higgins, Robert F., and Virginia Fuller. "Pervasis Therapeutics, Inc." Harvard Business School Case 807-026, December 2006. (Revised August 2008.)
- Winter 2019
- Article
Value-based Health Care: Lessons for the Anesthesiologist
By: J.A. Martin, B.L. Potter, T.F. Flanagan and T.W. Feeley
At one point or another in our life, we all become consumers of the health care industry. Indeed, health care affects everyone and encompasses a diverse set of services from childbirth, to illness prevention, to the management of chronic disease and end-of-life care.... View Details
Keywords: Value-based Health Care; Anesthesiologists; Health Care and Treatment; Value; Cost Management; Problems and Challenges; Health Industry; United States
Martin, J.A., B.L. Potter, T.F. Flanagan, and T.W. Feeley. "Value-based Health Care: Lessons for the Anesthesiologist." International Anesthesiology Clinics 57, no. 1 (Winter 2019): 63–80.