Publications

June 2020
Case

Breakthroughs at Blueprint Medicines

By: Richard G. Hamermesh, Kathy Giusti and Susie L. Ma

Precision medicine company Blueprint Medicines was building a successful track record for bringing drug therapies to market 40% faster than average. The company had spent $40 million dollars and two years building a compound library that became its drug development... View Details

Keywords: Precision Medicine; Cancer; Biotechnology; Drug Development; Strategy; Expansion; Science; Genetics; Information Technology; Entrepreneurship; Organizational Culture; Management; Growth and Development; Pharmaceutical Industry; United States; Cambridge; Massachusetts

2022
Working Paper

Overreaction and Diagnostic Expectations in Macroeconomics

By: Pedro Bordalo, Nicola Gennaioli and Andrei Shleifer

We present the case for the centrality of overreaction in expectations for addressing important challenges in finance and macroeconomics. First, non-rational expectations by market participants can be measured and modeled in ways that address some of the key challenges... View Details

Keywords: Overreaction; Rational Expectations; Macroeconomics; Market Participation; Social Psychology

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Spring 2013
Article

Accounting Quality, Stock Price Delay, and Future Stock Returns

By: Jeffrey Callen, Mozaffar N. Khan and Hai Lu

In frictionless capital markets with complete information and rational investors, stock prices adjust to new information instantaneously and completely. However, a substantial body of research studies information imperfections such as asymmetric information and... View Details

Keywords: Quality; Price; Stocks; Asset Pricing; Accounting

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14 Feb 2008
Working Paper Summaries

Laws vs. Contracts: Legal Origins, Shareholder Protections, and Ownership Concentration in Brazil, 1890-1950

Keywords: by Aldo Musacchio

January 2014 (Revised January 2014)
Case

Henry Schein: Doing Well by Doing Good?

By: Rebecca Henderson, Raffaella Sadun, Aldo Sesia and Russell Eisenstat

Henry Schein Inc., a distributor of supplies to dentist, physician, and veterinary practices, had sales approaching $9 billion and employed nearly 16,000 people. The company had experienced impressive growth under the leadership of Stanley Bergman and his executive... View Details

July 1991 (Revised August 1991)
Case

Philip Morris Companies, Inc. (A)

By: Samuel L. Hayes III

This large tobacco and diversified food processor is seeking to refinance debt funds raised to accomplish a large acquisition. It has filed a large "shelf" registration that authorizes it to issue during the subsequent two years. At the time of the case, the market... View Details

Keywords: Stocks; Initial Public Offering; Consumer Products Industry; United States

03 Apr 2012
First Look

First Look: April 3

personal conversation prior to the task. The effects of metacognitive CQ in enhancing creative collaboration were mediated by affect-based trust in Studies 2 and 3. Giving Time Gives You Time Authors:Cassie... View Details

Keywords: Carmen Nobel

27 Feb 2020
Sharpening Your Skills

How Following Best Business Practices Can Improve Health Care

Roughly one in 66 women has a better chance of leaving the hospital alive if their doctor is also a woman. Behavioral Economists Can Make You a Healthier Consumer and Smarter Marketer Psychological "interventions" companies can take to... View Details

Keywords: by Sean Silverthorne; Health; Medical Devices & Supplies

October 2002 (Revised December 2003)
Case

Collabrys, Inc. (A)-The Evolution of a Startup

By: Dorothy A. Leonard and Brian DeLacey

The CEO of a two-year-old start-up must now decide whether to become a technology provider or a service agency. In a time of enormous uncertainty about the viability of various business models for Internet-delivered services and products, Collabrys has survived the... View Details

Keywords: Risk and Uncertainty; Internet and the Web; Corporate Entrepreneurship; Corporate Strategy; Technological Innovation; Cost vs Benefits; Partners and Partnerships; Business Growth and Maturation; Business Startups; Corporate Finance; United States

27 Jan 2016
News

Kodak’s Old-School Response to Disruption

September 2002
Case

Align Technology, Inc.: Matching Manufacturing Capacity to Sales Demand

By: H. Kent Bowen and Jonathan P Groberg

Align Technology is a four-year-old medical products company that has invented a new product requiring new manufacturing processes. Demand for the new product has grown more slowly than initial forecasts predicted, and the cost structure is preventing the company from... View Details

Keywords: Health Care and Treatment; Collaborative Innovation and Invention; Problems and Challenges; Product; Forecasting and Prediction; Marketing Strategy; Sales; Demand and Consumers; Production; Health Industry

29 Sep 2023
Blog Post

HBS Latino Student Association Spotlight: Reyna Pacheco Rios (MBA 2025)

Tijuana, Mexico, where I was born, was just a drive away. While I was in physical proximity to my roots, I have always felt like I was walking a tightrope. I spent a lot of time trying to balance feeling both Mexican and American, often... View Details

2024
Working Paper

Valuing Stocks With Earnings

By: Sebastian Hillenbrand and Odhrain McCarthy

We show that commonly used aggregate earnings are several times as volatile as stock prices over the last three decades. Movements in the price-earnings ratio are thus entirely explained by earnings growth and unrelated to future returns. As an alternative to the... View Details

Keywords: Price; Investment Portfolio; Stocks; Behavioral Finance; Accounting