Publications

September 2017 (Revised July 2023)
Case

Adaptive Platform Trials: The Clinical Trial of the Future?

By: Ariel D. Stern and Sarah Mehta

In July 2017, Dr. Brian M. Alexander, president and CEO of the AGILE Research Foundation, was preparing to launch a new type of clinical trial—an adaptive platform trial—to study potential therapies for glioblastoma (GBM), an aggressive form of brain cancer.... View Details

Keywords: Clinical Trials; Cancer; Adaptive Platform Trials; Platform Trials; Adaptive Trials; Glioblastoma; Health; Health Care and Treatment; Health Testing and Trials; Business Strategy; Innovation Strategy; Health Industry; United States

October 2012
Case

Riding the Wave of Technological Change at RE/MAX, LLC.

By: Lynda M. Applegate, Ramiro Montealegre and Jeffrey Sweeney

David Liniger, cofounder of RE/MAX, LLC., wondered if his business was prepared to exploit the next wave of business opportunities in the real estate market. This industry had moved from one in which broker/owners controlled all of the consumers' access to information,... View Details

Keywords: General Management; Business Strategy; Entrepreneurship; Business Model; Information Technology; Transformation; Organizational Change and Adaptation

25 Aug 2017
Blog Post

HBS Interns: Summer Takeovers

The summer internship experience provides students the opportunity to apply their learnings to a real business environment and continue exploring their career interests. With the majority of the class completing internships all over the... View Details

Keywords: All Industries

November 1996 (Revised March 1998)
Case

Vallourec's Venture into Metal Injection Molding

By: Clayton M. Christensen

Vallourec, a leading maker of seamless tubing, developed a radically new technology that used steel powders to create the tubes. To ensure a supply source, Vallourec ultimately had to acquire its supplier of metal powder, and then, to build the volume required to... View Details

Keywords: Technology; Business Model; Diversification; Innovation and Management; Manufacturing Industry

Find at Harvard

April 2017 (Revised February 2020)
Supplement

edaixi (eWash): Digital Transformation of Laundry Services (B)

By: Feng Zhu, Weiru Chen, Chuang Chen and Ciwu Lin

Founded in 2013 as a laundry service featuring online ordering for home pickup and delivery, China’s edaixi (eWash) illustrated the online-to-offline (O2O) business model. As yet unclear in 2016 was the optimal way to organize third-party laundry service providers,... View Details

Keywords: Laundry; O2O; Online-to-offline; Service Operations; Business Model; Digital Platforms; Transformation; Service Industry; China

Research Summary

Current Research

Ian studies extrinsic rewards -- monetary incentives from formal compensation systems, as well as other formal and informal external rewards-- in order to help businesses understand the tensions and tradeoffs inherent in motivating employees. His research takes a... View Details

March 2019 (Revised June 2021)
Case

HelloSelf: Foundation

By: John R. Wells and Benjamin Weinstock

On January 6, 2019, HelloSelf, a London-based “BrainTech” company, founded a year earlier by Charles Wells, soft launched. The proposition was simply to help its members “Be your Best Self.” The company provided its registered members with access to a clinical... View Details

January 2018
Article

The Central and Unacknowledged Role of the U.S. Food and Drug Administration in the Design and Execution of Medical Device Pivotal Trials

By: Aaron V. Kaplan and Ariel D. Stern

The introduction of new medical devices has transformed cardiovascular care in recent decades. Devices, such as heart valves, pacemakers, stents, ventricular assist devices, and implantable defibrillators, have prolonged and improved the quality of life for millions of... View Details

Keywords: Health Testing and Trials; Business and Government Relations; Governing Rules, Regulations, and Reforms; Information Publishing; Medical Devices and Supplies Industry; United States

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18 Jul 2006
First Look

First Look: July 18, 2006

Working PapersNone available this week Cases & Course MaterialsThe Company Sale Process Author:William E. Fruhan Jr. Harvard Business School Note 206-108 Lays out the steps, timeline, and process by which a company is sold.... View Details

Keywords: Sean Silverthorne

September 2009 (Revised April 2011)
Supplement

Integrated Project Delivery at Autodesk, Inc. (C)

By: Amy C. Edmondson and Faaiza Rashid

Describes Autodesk's engagement in Integrated Project Delivery—a new model of risk management, inter-firm teamwork, and multi-objective (aesthetic, cost, and sustainability) optimization in building projects. In 2008, Autodesk, Inc. the world's largest design software... View Details

Keywords: Risk Management; Groups and Teams; Goals and Objectives; Collaborative Innovation and Invention; Integration; Construction Industry