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- All HBS Web
(296)
- Faculty Publications (74)
- October 2020
- Technical Note
Organizational Reinvention
By: Ryan Raffaelli
This note is designed to introduce students to the fundamental concepts of leading innovation in established organizations. Reinvention is a process whereby organizations respond to changes in the environment that threaten their core business model, technologies,... View Details
Keywords: Innovation And Strategy; Leadership And Change Management; Organizational Ambidexterity; Exploration And Exploitation; Innovation and Management; Innovation Leadership; Leading Change; Technology Adoption; Change Management; Organizational Change and Adaptation
Raffaelli, Ryan. "Organizational Reinvention." Harvard Business School Technical Note 421-041, October 2020.
- Article
Assessing the Training Costs and Work of Diagnostic Radiology Residents Using Key Performance Indicators—An Observational Study
By: Robert S. Kaplan, Marta E. Heilbrun, Brad Poss, Luca Boi, Yoshimi Anzai and Nan Hu
Kaplan, Robert S., Marta E. Heilbrun, Brad Poss, Luca Boi, Yoshimi Anzai, and Nan Hu. "Assessing the Training Costs and Work of Diagnostic Radiology Residents Using Key Performance Indicators—An Observational Study." Academic Radiology 27, no. 7 (July 2020): 1025–1032.
- Article
Development of a Deep Learning Algorithm for Periapical Disease Detection in Dental Radiographs
By: Michael G. Endres, Florian Hillen, Marios Salloumis, Ahmad R. Sedaghat, Stefan M. Niehues, Olivia Quatela, Henning Hanken, Ralf Smeets, Benedicta Beck-Broichsitter, Carsten Rendenbach, Karim R. Lakhani, Max Helland and Robert A. Gaudin
Periapical radiolucencies, which can be detected on panoramic radiographs, are one of the most common radiographic findings in dentistry and have a differential diagnosis including infections, granuloma, cysts, and tumors. In this study, we seek to investigate the... View Details
Keywords: Artificial Intelligence; Diagnosis; Computer-assisted; Image Interpretation; Machine Learning; Radiography; Panoramic Radiograph; AI and Machine Learning
Endres, Michael G., Florian Hillen, Marios Salloumis, Ahmad R. Sedaghat, Stefan M. Niehues, Olivia Quatela, Henning Hanken, Ralf Smeets, Benedicta Beck-Broichsitter, Carsten Rendenbach, Karim R. Lakhani, Max Helland, and Robert A. Gaudin. "Development of a Deep Learning Algorithm for Periapical Disease Detection in Dental Radiographs." Diagnostics 10, no. 6 (June 2020).
- 26 Apr 2020
- Other Presentation
Towards Modeling the Variability of Human Attention
By: Kuno Kim, Megumi Sano, Julian De Freitas, Daniel Yamins and Nick Haber
Children exhibit extraordinary exploratory behaviors hypothesized to contribute to the building of models of their world. Harnessing this capacity in artificial systems promises not only more flexible technology but also cognitive models of the developmental processes... View Details
Keywords: Exploratory Learning Behaviors; Modeling; Artificial Intelligence; AI and Machine Learning
Kim, Kuno, Megumi Sano, Julian De Freitas, Daniel Yamins, and Nick Haber. "Towards Modeling the Variability of Human Attention." In Bridging AI and Cognitive Science (BAICS) Workshop. 8th International Conference on Learning Representations (ICLR), April 26, 2020.
- March 2020
- Article
Diagnosing Missing Always at Random in Multivariate Data
By: Iavor I. Bojinov, Natesh S. Pillai and Donald B. Rubin
Models for analyzing multivariate data sets with missing values require strong, often assessable, assumptions. The most common of these is that the mechanism that created the missing data is ignorable—a twofold assumption dependent on the mode of inference. The first... View Details
Keywords: Missing Data; Diagnostic Tools; Sensitivity Analysis; Hypothesis Testing; Missing At Random; Row Exchangeability; Analytics and Data Science; Mathematical Methods
Bojinov, Iavor I., Natesh S. Pillai, and Donald B. Rubin. "Diagnosing Missing Always at Random in Multivariate Data." Biometrika 107, no. 1 (March 2020): 246–253.
- 2019
- Case
Krueger-Gilbert Health Physics: Can a Serial Acquisition Strategy Work for a Diagnostic Consulting Firm?
By: Jason Pananos and A.J. Wasserstein
Pananos, Jason, and A.J. Wasserstein. "Krueger-Gilbert Health Physics: Can a Serial Acquisition Strategy Work for a Diagnostic Consulting Firm?" Yale School of Management Case 19-014, 2019.
- 2024
- Working Paper
Computed Tomography (CT)--Beyond Traditional X-Rays: Case Histories of Transformational Advances
By: Amar Bhidé, Srikant M. Datar and Katherine Stebbins
This case history describes how Computed Tomography (CT) scanners - that combine Xrays
and computers to image soft tissues of the brain and other organs -- have become a widely used
diagnostic tool. Specifically, we chronicle the 1) initial development of CT... View Details
Keywords: Health Care and Treatment; Technological Innovation; Innovation Strategy; Technology Adoption; Collaborative Innovation and Invention; Innovation and Invention; Governing Rules, Regulations, and Reforms
Bhidé, Amar, Srikant M. Datar, and Katherine Stebbins. "Computed Tomography (CT)--Beyond Traditional X-Rays: Case Histories of Transformational Advances." Harvard Business School Working Paper, No. 20-004, July 2019. (Revised May 2024.)
- 2024
- Working Paper
Gastrointestinal Endoscopy--Without Cutting In: Case Histories of Transformational Advances
By: Amar Bhidé, Srikant M. Datar and Katherine Stebbins
This case history describes how endoscopy transformed the diagnosis of ulcers, cancerous polyps, and other alimentary canal diseases and enabled “minimally invasive” surgeries to treat such diseases. Specifically, we chronicle how: 1) flexible glass fiber endoscopes... View Details
Keywords: Health Care and Treatment; Technological Innovation; Innovation Strategy; Technology Adoption; Collaborative Innovation and Invention; Innovation and Invention; Governing Rules, Regulations, and Reforms
Bhidé, Amar, Srikant M. Datar, and Katherine Stebbins. "Gastrointestinal Endoscopy--Without Cutting In: Case Histories of Transformational Advances." Harvard Business School Working Paper, No. 20-005, July 2019. (Revised May 2024.)
- 2024
- Working Paper
Ultrasound Imaging--Cheap, Versatile, and Safe: Case Histories of Transformational Advances
By: Amar Bhidé, Srikant M. Datar and Katherine Stebbins
This case history describes how efforts on multiple fronts, including advocacy, training, and technological development, made ultrasound the second most commonly used diagnostic imaging technology (after X-rays). Specifically, we chronicle 1) ultrasound’s development... View Details
Keywords: Health Care and Treatment; Technological Innovation; Innovation Strategy; Technology Adoption; Collaborative Innovation and Invention; Innovation and Invention; Governing Rules, Regulations, and Reforms
Bhidé, Amar, Srikant M. Datar, and Katherine Stebbins. "Ultrasound Imaging--Cheap, Versatile, and Safe: Case Histories of Transformational Advances." Harvard Business School Working Paper, No. 20-003, July 2019. (Revised May 2024.)
- 2019
- Article
Can Big Data Improve Firm Decision Quality? The Role of Data Quality and Data Diagnosticity
By: Maryam Ghasemaghaei and Goran Calic
Anecdotal evidence suggests that, despite the large variety of data, the huge volume of generated data, and the fast velocity of obtaining data (i.e., big data), quality of big data is far from perfect. Therefore, many firms defer collecting and integrating big data as... View Details
Ghasemaghaei, Maryam, and Goran Calic. "Can Big Data Improve Firm Decision Quality? The Role of Data Quality and Data Diagnosticity." Decision Support Systems 120 (2019): 38–49.
- 2019
- Chapter
Characterizing the Drug Development Pipeline for Precision Medicines
By: Amitabh Chandra, Craig Garthwaite and Ariel Dora Stern
BOOK ABSTRACT: Personalized and precision medicine (PPM)—the targeting of therapies according to an individual’s genetic, environmental, or lifestyle characteristics—is becoming an increasingly important approach in health care treatment and prevention. The advancement... View Details
Chandra, Amitabh, Craig Garthwaite, and Ariel Dora Stern. "Characterizing the Drug Development Pipeline for Precision Medicines." Chap. 5 in Economic Dimensions of Personalized and Precision Medicine, edited by Ernest R. Berndt, Dana P. Goldman, and John W. Rowe, 115–158. University of Chicago Press, 2019.
- 2018
- Working Paper
Diagnostic Bubbles
By: Pedro Bordalo, Nicola Gennaioli, Spencer Yongwook Kwon and Andrei Shleifer
We introduce diagnostic expectations into a standard setting of price formation in which investors learn about the fundamental value of an asset and trade it. We study the interaction of diagnostic expectations with two well-known mechanisms: learning from prices and... View Details
Bordalo, Pedro, Nicola Gennaioli, Spencer Yongwook Kwon, and Andrei Shleifer. "Diagnostic Bubbles." NBER Working Paper Series, No. 25399, December 2018.
- February 2018
- Article
Diagnostic Expectations and Credit Cycles
By: Pedro Bordalo, Nicola Gennaioli and Andrei Shleifer
Bordalo, Pedro, Nicola Gennaioli, and Andrei Shleifer. "Diagnostic Expectations and Credit Cycles." Journal of Finance 73, no. 1 (February 2018): 199–227.
- Article
Stop the Meeting Madness: How to Free Up Time for Meaningful Work
By: Leslie Perlow, Constance Noonan Hadley and Eunice Eun
Many executives feel overwhelmed by meetings, and no wonder: On average, they spend nearly 23 hours a week in them, up from less than 10 hours in the 1960s. What’s more, the meetings are often poorly timed, badly run, or both. We can all joke about how painful they... View Details
Keywords: Time Management; Performance Efficiency; Organizational Change and Adaptation; Performance Improvement
Perlow, Leslie, Constance Noonan Hadley, and Eunice Eun. "Stop the Meeting Madness: How to Free Up Time for Meaningful Work." Harvard Business Review 95, no. 4 (July–August 2017): 62–69.
- December 2016 (Revised May 2018)
- Module Note
Strategy Execution Module 15: Using the Levers of Control to Implement Strategy
By: Robert Simons
This module reading pulls together key concepts and techniques from the Strategy Execution series into an integrated model—the levers of control. The four levers are: (1) belief systems, (2) boundary systems, (3) diagnostic control systems, and (4) interactive control... View Details
Keywords: Management Control Systems; Implementing Strategy; Execution; Levers Of Control; Balancing Innovation And Control; Managing Growing Businesses; Turn Around Management; Human Behavior; Organizational Life Cycle; Strategy; Management Systems; Performance; Measurement and Metrics; Management Analysis, Tools, and Techniques; Behavior
Simons, Robert. "Strategy Execution Module 15: Using the Levers of Control to Implement Strategy." Harvard Business School Module Note 117-115, December 2016. (Revised May 2018.)
- November 2016 (Revised December 2016)
- Module Note
Strategy Execution Module 13: Identifying Strategic Risk
By: Robert Simons
This module reading begins by describing the three sources of strategic risk—operations risk, asset impairment risk, and competitive risk—and demonstrates how these risks can undermine an entire business. To assist in the identification of these risks, the risk... View Details
Keywords: Management Control Systems; Implementing Strategy; Execution; Risk Assessment; Operational Control; Asset Impairment; Franchise Risk; Fraud; Strategy; Information Management
Simons, Robert. "Strategy Execution Module 13: Identifying Strategic Risk." Harvard Business School Module Note 117-113, November 2016. (Revised December 2016.)
- November 2016 (Revised December 2016)
- Module Note
Strategy Execution Module 11: Using Diagnostic and Interactive Control Systems
By: Robert Simons
This module reading introduces diagnostic and interactive control systems. Diagnostic control systems are the management-by-exception systems that managers use to monitor the achievement of their business strategy. Interactive control systems are the systems that top... View Details
Keywords: Management Control Systems; Implementing Strategy; Execution; Performance Measurement; Diagnostic Control Systems; Interactive Control Systems; Emergent Strategy; Goal Setting; Incentives; Strategy; Motivation and Incentives; Goals and Objectives; Management Systems; Performance Evaluation
Simons, Robert. "Strategy Execution Module 11: Using Diagnostic and Interactive Control Systems." Harvard Business School Module Note 117-111, November 2016. (Revised December 2016.)
- August 2016 (Revised July 2019)
- Case
Alere
By: Raffaella Sadun, Catherine Slater and Channing Spencer
The Board of Alere, Inc., a leading medical diagnostic firm, is evaluating the offer made by Ron Zwanziger, the firm’s founder and former CEO, to acquire the company and take it private. The offer arrives at the end of a tumultuous year for the company, which saw... View Details
- February 2016 (Revised September 2017)
- Case
Neurotrack and the Alzheimer's Puzzle
By: Richard G. Hamermesh, Liz Kind and Carin-Isabel Knoop
Elli Kaplan founded Neurotrack in 2012 with a breakthrough noninvasive cognitive diagnostics test that will detect Alzheimer's disease in its earliest pre-symptomatic stages. While the company has gained great traction in the three years since it was started, with no... View Details
Keywords: Alzheimer's Disease; Diagnostics; Healthcare; Entrepreneurship; Health Disorders; Science-Based Business; Business Model; Medical Devices and Supplies Industry; United States
Hamermesh, Richard G., Liz Kind, and Carin-Isabel Knoop. "Neurotrack and the Alzheimer's Puzzle." Harvard Business School Case 816-072, February 2016. (Revised September 2017.)
- February 2016 (Revised September 2017)
- Case
Mohamed Azab and Seha Capital
By: Richard G. Hamermesh and Sarah McAra
In January 2011, Mohamed Azab, founder and CEO of health care investment firm Seha Capital, made his first health care investment in Hassab Labs, a diagnostic lab in Alexandria, Egypt. Weeks later, a revolution erupted across the country as the Arab Spring swept... View Details
Keywords: Health Care; Health; Pan-Africa; Health Care Investment; Financing; Developing World; Entrepreneurship; Health Care and Treatment; Investment; Financing and Loans; Developing Countries and Economies; Egypt; Africa
Hamermesh, Richard G., and Sarah McAra. "Mohamed Azab and Seha Capital." Harvard Business School Case 816-066, February 2016. (Revised September 2017.)