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All HBS Web
(183)
- News (48)
- Research (88)
- Events (2)
- Multimedia (3)
- Faculty Publications (46)
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- 12 Jul 2016
- First Look
July 12, 2016
spending. Whereas traditional (small-molecule) drugs have historically faced price competition from generic drugs after patent expiration, biosimilars—biologic drugs that have been shown to be therapeutically equivalent to an already approved View Details
Keywords:
Sean Silverthorne
- Research Summary
Risk, Trust and Escalation Behavior of Owner Managers
Professor Montgomery and Professor Deepak Malhotra (HBS), together with scientists from Harvard's Program on Evolutionary Dynamics, are studying risk-related decision making of owner managers in newly-founded and established companies. This experimental...
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- March 2018 (Revised March 2019)
- Case
Gender and Free Speech at Google (A)
By: Nien-hê Hsieh, Martha J. Crawford and Sarah Mehta
In August 2017, Google fired James Damore, a 28-year-old software engineer who had been employed by the company since 2013. The move came after Damore penned an internal company memo titled “Google’s Ideological Echo Chamber,” which posited that innate biological...
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Keywords:
Free Speech;
Representation;
Diversity;
Gender;
Race;
Human Resources;
Employees;
Employee Relationship Management;
Recruitment;
Selection and Staffing;
Labor;
Employment;
Lawsuits and Litigation;
Organizational Culture;
Technology Industry;
United States;
California
Hsieh, Nien-hê, Martha J. Crawford, and Sarah Mehta. "Gender and Free Speech at Google (A)." Harvard Business School Case 318-085, March 2018. (Revised March 2019.)
- May 2016
- Case
AbbVie
By: Kevin Schulman, Laura Little, Samyukta Mullangi and Stephen Schleicher
This case focuses on the impact of a novel regulatory pathway, the biosimilars pathway, on the strategy of a major pharmaceutical firm that finds its largest product (60% of revenue) at risk. The case reviews the rationale for the pathway, the emerging biosimilars...
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- June 2016 (Revised August 2019)
- Case
Numenta: Inventing and (or) Commercializing AI
By: David B. Yoffie, Liz Kind and David Ben Shimol
In March 2016, Donna Dubinsky (co-founder and CEO) and Jeff Hawkins (co-founder) were struggling with a key question: Could Numenta be successful in both creating fundamental technology and building a commercial business? Located in Redwood City, CA, Numenta was...
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Keywords:
Artificial Intelligence;
Machine Intelligence;
Machine Learning;
Strategy;
Business Model;
Entrepreneurship;
Information;
Technological Innovation;
Research;
Research and Development;
Information Technology;
Applications and Software;
Technology Adoption;
Digital Platforms;
Commercialization;
AI and Machine Learning
Yoffie, David B., Liz Kind, and David Ben Shimol. "Numenta: Inventing and (or) Commercializing AI." Harvard Business School Case 716-469, June 2016. (Revised August 2019.)
- Research Summary
Understanding Human Nature
By: Nitin Nohria
Recent advances in biological sciences provide great insights into the workings of the human brain and thereby into human nature. Drawing upon this research, my colleague Paul Lawrence and I propose a neo-Darwinian theory of human motivation based on four basic human...
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- Article
Matriarch: A Python Library for Materials Architecture
By: Tristan Giesa, Ravi Jagadeesan, David I. Spivak and Markus J. Buehler
Biological materials, such as proteins, often have a hierarchical structure ranging from basic building blocks at the nanoscale (e.g., amino acids) to assembled structures at the macroscale (e.g., fibers). Current software for materials engineering allows the user to...
View Details
Keywords:
Building Block;
Category Theory;
Hierarchical Protein Materials;
Molecular Design;
Open-Source Software;
Structure Creation
Giesa, Tristan, Ravi Jagadeesan, David I. Spivak, and Markus J. Buehler. "Matriarch: A Python Library for Materials Architecture." ACS Biomaterials Science & Engineering 1, no. 10 (October 2015): 1009–1015.
- October 2022
- Case
Afrigen Biologics: Vaccines for the Global South
By: Debora L. Spar and Julia Comeau
The majority of vaccines used on the continent of Africa (99%) are produced offshore. This makes African nations reliant on the West for major health care needs, a problem which was exacerbated by the COVID-19 pandemic. Afrigen Biologics (in partnership with the WHO)...
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Keywords:
Vaccination;
Vaccine;
mRNA;
COVID;
COVID-19;
Inequity;
Hub-and-spoke;
Health Care and Treatment;
Health Pandemics;
Production;
Social Issues;
Business and Government Relations;
South Africa;
Africa
Spar, Debora L., and Julia Comeau. "Afrigen Biologics: Vaccines for the Global South." Harvard Business School Case 323-030, October 2022.
- October 2023
- Article
Laboratory Safety and Research Productivity
By: Alberto Galasso, Hong Luo and Brooklynn Zhu
Are laboratory safety practices a tax on scientific productivity? We examine this question by exploiting the substantial increase in safety regulations at the University of California following the shocking accidental death of a research assistant in 2008....
View Details
Keywords:
Economics Of Science;
Risk Perception;
Safety Regulations;
Governing Rules, Regulations, and Reforms;
Working Conditions;
Safety;
Performance Productivity
Galasso, Alberto, Hong Luo, and Brooklynn Zhu. "Laboratory Safety and Research Productivity." Art. 104827. Research Policy 52, no. 8 (October 2023).
- 2009
- Case
The Prediction Lover's Handbook
By: Thomas H. Davenport and Jeanne G. Harris
When picking assessment tools to inform better decisions about future paths, executives are faced with a wide variety of options--some of which are well established, while others are in early stages of development. The authors provide an insider's guide to prediction...
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Davenport, Thomas H., and Jeanne G. Harris. "The Prediction Lover's Handbook." 2009.
- 14 Nov 2017
- First Look
New Research and Ideas: November 14, 2017
victimized. We measure biological markers of stress and behavioral indices of cognitive control before and after treated participants watch a series of real, crime-related videos (while the control group watches non-crime-related videos)....
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Keywords:
Carmen Nobel
- 2020
- Working Paper
A General Theory of Identification
By: Iavor Bojinov and Guillaume Basse
What does it mean to say that a quantity is identifiable from the data? Statisticians seem to agree
on a definition in the context of parametric statistical models — roughly, a parameter θ in a model
P = {Pθ : θ ∈ Θ} is identifiable if the mapping θ 7→ Pθ is injective....
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Bojinov, Iavor, and Guillaume Basse. "A General Theory of Identification." Harvard Business School Working Paper, No. 20-086, February 2020.
- November 2016
- Case
QuintilesIMS: Biosimilar Marketing in England
By: John A. Quelch and Emily C. Boudreau
QuintilesIMS was a leading healthcare consulting firm best known for its data and information offerings as well as its market research and management consulting services for life science companies. By 2015, the company was expanding beyond the biopharmaceutical...
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Keywords:
Health;
Pharmaceutical Industry;
Biotech;
Marketing;
Health Care and Treatment;
Biotechnology Industry;
England
Quelch, John A., and Emily C. Boudreau. "QuintilesIMS: Biosimilar Marketing in England." Harvard Business School Case 517-054, November 2016.
- Article
The Power in Demography: Women's Social Constructions of Gender Identity at Work
By: R. J. Ely
This study examined how women's proportional representation in the upper echelons of organizations affects professional women's social constructions of gender difference and gender identity at work. Qualitative and quantitative data were used. Results suggest that sex...
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Ely, R. J. "The Power in Demography: Women's Social Constructions of Gender Identity at Work." Academy of Management Journal 38, no. 3 (June 1995): 589–634. (Winner, Academy of Management Journal Impact Award, 2021.)
- Article
The Information Technology Ecosystem: Structure, Health, and Performance
By: Marco Iansiti and Gregory L. Richards
A number of modern industries are organized as complex networks of firms whose integrated efforts are necessary to deliver value to end customers. The complexity of these networks, or business ecosystems, and the associated interdependencies among firms, make... View Details
Keywords:
Business Ventures;
Networks;
Value;
Customers;
Performance Productivity;
Product;
Applications and Software;
Innovation and Invention;
Competition;
Business Model;
Information Infrastructure;
Information Technology Industry
Iansiti, Marco, and Gregory L. Richards. "The Information Technology Ecosystem: Structure, Health, and Performance." Antitrust Bulletin 51, no. 1 (Spring 2006).
- June 2024
- Article
Economics of Enhanced Methane Oxidation Relative to Carbon Dioxide Removal
By: Conor Hickey and Myles Allen
Mitigating short-term global warming is imperative, and a key strategy involves reducing atmospheric methane (CH4) due to its high radiative forcing and short lifespan. This objective can be achieved through methods such as oxidising methane at its source or...
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Keywords:
Greenhouse Gas Mitigation;
Climate Change;
Environmental Regulation;
Pollutants;
Research;
Measurement and Metrics
Hickey, Conor, and Myles Allen. "Economics of Enhanced Methane Oxidation Relative to Carbon Dioxide Removal." Art. 4043. Environmental Research Letters 19, no. 6 (June 2024).
- Article
No Evidence For an Effect of Testosterone Administration on Delay Discounting in Male University Students
By: Georgia Rada Ortner, Matthias Wibral, Anke Becker, Thomas Dohmen, Dietrich Klingmüller, Armin Falk and Bernd Weber
Intertemporal choices between a smaller sooner and a larger delayed reward are one of the most important types of decisions humans face in their everyday life. The degree to which individuals discount delayed rewards correlates with impulsiveness. Steep delay...
View Details
Keywords:
Delay Discounting;
Impulsiveness;
Intertemporal Choice;
Testosterone;
Decision Making;
Behavior;
Personal Characteristics
Rada Ortner, Georgia, Matthias Wibral, Anke Becker, Thomas Dohmen, Dietrich Klingmüller, Armin Falk, and Bernd Weber. "No Evidence For an Effect of Testosterone Administration on Delay Discounting in Male University Students." Psychoneuroendocrinology 38, no. 9 (September 2013): 1814–1818.
- September 2019 (Revised August 2020)
- Case
Engineering an Inclusive Bioeconomy
By: Tarun Khanna, Raffaella Sadun and Susie L. Ma
In 2019, entrepreneur Juan Carlos Castilla-Rubio was developing a project he hoped could generate and share wealth from the natural resources of the Amazon without destroying those resources. His idea, called Earth Bank of Codes (EBC), would create a library of the...
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Keywords:
Decision Making;
Development Economics;
Entrepreneurship;
Innovation and Invention;
Intellectual Property;
Emerging Markets;
Market Design;
Marketplace Matching;
Science;
Genetics;
Natural Environment;
Environmental Sustainability;
Climate Change;
Social Enterprise;
Strategy;
Strategic Planning;
Information Technology;
Ownership;
Social Psychology;
Trust;
Society;
Biotechnology Industry;
South America;
Amazon Basin
Khanna, Tarun, Raffaella Sadun, and Susie L. Ma. "Engineering an Inclusive Bioeconomy." Harvard Business School Case 720-356, September 2019. (Revised August 2020.)
- July 2011 (Revised January 2013)
- Case
Digital Microscopy Is Making Me Crazy!
By: Willy Shih
For Carl Zeiss Microimaging, modular hardware and software enabled customers to tailor Zeiss's broad range of microscopy systems hardware and software to meet a wide range of needs from basic scientific research in the biological and medical sciences to clinical...
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Keywords:
Information Infrastructure;
Applications and Software;
Corporate Strategy;
Disruptive Innovation;
Science-Based Business;
Management Analysis, Tools, and Techniques;
Business Conglomerates;
Digital Platforms;
Opportunities;
Medical Devices and Supplies Industry;
Computer Industry
Shih, Willy. "Digital Microscopy Is Making Me Crazy!" Harvard Business School Case 612-002, July 2011. (Revised January 2013.)
- 2011
- Book
Capitalism: Its Origins and Evolution as a System of Governance
By: Bruce R. Scott
Capitalism, as defined in this book, is an indirect, three-level system of governance for economic relationships (i.e., economic, administrative, and political). Whereas economic markets can coordinate supply and demand within an existing system thanks to the invisible...
View Details
Keywords:
Economic Systems;
Price;
Governance;
Government and Politics;
Books;
Markets;
Relationships;
System
Scott, Bruce R. Capitalism: Its Origins and Evolution as a System of Governance. Springer, 2011.