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  • All HBS Web  (2,149)
    • News  (417)
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  • Faculty Publications  (446)
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  • February 2021
  • Case

Digital Manufacturing at Amgen

By: Shane Greenstein, Kyle R. Myers and Sarah Mehta
This case discusses efforts made by biotechnology (biotech) company Amgen to introduce digital technologies into its manufacturing processes. Doing so is complicated by the fact that the process for manufacturing biologics—or therapeutics made from living cells—is... View Details
Keywords: Digital Technologies; Change; Change Management; Decision Making; Cost vs Benefits; Decisions; Information; Analytics and Data Science; Innovation and Invention; Innovation and Management; Innovation Leadership; Innovation Strategy; Technological Innovation; Jobs and Positions; Knowledge; Leadership; Organizational Culture; Science; Strategy; Information Technology; Technology Adoption; Biotechnology Industry; Pharmaceutical Industry; United States; California; Puerto Rico; Rhode Island
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Greenstein, Shane, Kyle R. Myers, and Sarah Mehta. "Digital Manufacturing at Amgen." Harvard Business School Case 621-008, February 2021.
  • 2016
  • Article

Penalized Fast Subset Scanning

By: Skyler Speakman, Sriram Somanchi, Edward McFowland III and Daniel B. Neill
We present the penalized fast subset scan (PFSS), a new and general framework for scalable and accurate pattern detection. PFSS enables exact and efficient identification of the most anomalous subsets of the data, as measured by a likelihood ratio scan statistic.... View Details
Keywords: Disease Surveillance; Likelihood Ratio Statistic; Pattern Detection; Scan Statistic; Mathematical Methods
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Speakman, Skyler, Sriram Somanchi, Edward McFowland III, and Daniel B. Neill. "Penalized Fast Subset Scanning." Journal of Computational and Graphical Statistics 25, no. 2 (2016): 382–404. (Selected for “Best of JCGS” invited session by the journal’s editor in chief.)
  • January 2022
  • Article

Investing Outside the Box: Evidence from Alternative Vehicles in Private Equity

By: Josh Lerner, Jason Mao, Antoinette Schoar and Nan R. Zhang
This paper uses previously unexplored custodial data to examine the use of alternative investment vehicles in private equity (PE) over four decades. We document a steep increase in the capital directed to alternative vehicles, with these vehicles approaching a 40%... View Details
Keywords: Alternative Investment Vehicles; Investment Funds; Private Equity; Venture Capital; Performance
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Lerner, Josh, Jason Mao, Antoinette Schoar, and Nan R. Zhang. "Investing Outside the Box: Evidence from Alternative Vehicles in Private Equity." Journal of Financial Economics 143, no. 1 (January 2022): 359–380. (Won the 2022 Doriot Award for the Best Private Equity Research Paper.)
  • 2010
  • Book

Buy-In: Saving Your Good Idea from Getting Shot Down

By: John P. Kotter and Lorne A. Whitehead
You've got a good idea. You know it could make a crucial difference for you, your organization, your community. You present it to the group but get confounding questions, inane comments, and verbal bullets in return. Before you know what's happened, your idea is dead,... View Details
Keywords: Communication Intention and Meaning; Cost vs Benefits; Problems and Challenges; Interests; Value
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Kotter, John P., and Lorne A. Whitehead. Buy-In: Saving Your Good Idea from Getting Shot Down. Harvard Business Review Press, 2010.
  • February 2019 (Revised July 2019)
  • Case

Sales Force Management at Nobel Ilac

By: Doug J. Chung and Gamze Yucaoglu
Nobel Ilac was a Turkish generic pharmaceutical company marketing more than 100 drugs in 20 countries and, as of 2017, had over 2,500 employees worldwide. Nobel had implemented a transformation strategy—more specifically, a customer segmentation plan—whereby the sales... View Details
Keywords: Sales Strategy; Compensation; Employee Retention; Recruiting; Pharmaceuticals; Salesforce Management; Strategy; Organizational Design; Human Resources; Compensation and Benefits; Employees; Retention; Recruitment; Pharmaceutical Industry; Turkey
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Chung, Doug J., and Gamze Yucaoglu. "Sales Force Management at Nobel Ilac." Harvard Business School Case 519-067, February 2019. (Revised July 2019.)
  • June 2012
  • Case

Innovating at AT&T: Partnering to Lead the Broadband Revolution

By: Lynda M. Applegate, Phillip Andrews and Kerry Herman
In 2010, the U.S. retail market value for next-generation non-handset wirelessly-enabled devices was just over $1 billion. By 2011 it had grown 1,141% to $13.2 billion and was forecast to reach $24.7 billion in 2015. At the same time, user demand for data was surging... View Details
Keywords: Innovation & Entrepreneurship; Team Leadership; Emerging Technologies; Business Models; Business To Business; Corporate Vision; Growth Strategy; Corporate Culture; Innovation and Invention; Corporate Entrepreneurship; Partners and Partnerships; Leadership; Mobile and Wireless Technology; Growth and Development Strategy; Globalized Firms and Management; Business Model; Technology Industry; United States
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Applegate, Lynda M., Phillip Andrews, and Kerry Herman. "Innovating at AT&T: Partnering to Lead the Broadband Revolution." Harvard Business School Case 812-124, June 2012.
  • 2015
  • Chapter

Consumer Neuroscience: Revealing Meaningful Relationships Between Brain and Consumer Behavior

By: Hilke Plassmann and Uma R. Karmarkar
The goal of this chapter is to give an overview of the nascent field of consumer neuroscience and discuss when and how it is useful to integrate the "black box" of the consumer's brain into consumer psychology. To reach this goal, we first briefly outline several... View Details
Keywords: Consumer Behavior; Cognition and Thinking
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Plassmann, Hilke, and Uma R. Karmarkar. "Consumer Neuroscience: Revealing Meaningful Relationships Between Brain and Consumer Behavior." Chap. 6 in The Cambridge Handbook of Consumer Psychology, edited by Michael I. Norton, Derek D. Rucker, and Cait Lamberton, 152–179. New York: Cambridge University Press, 2015.
  • 13 Apr 2007
  • Working Paper Summaries

Incorporating Price and Inventory Endogeneity in Firm-Level Sales Forecasting

Keywords: by Saravanan Kesavan, Vishal Gaur & Ananth Raman; Retail
  • 2021
  • Article

Designing, Not Checking, for Policy Robustness: An Example with Optimal Taxation

By: Benjamin B. Lockwood, Afras Sial and Matthew C. Weinzierl
Economists typically check the robustness of their results by comparing them across plausible ranges of parameter values and model structures. A preferable approach to robustness—for the purposes of policymaking and evaluation—is to design policy that takes these... View Details
Keywords: Optimal Taxation; Income Tax; Social Welfare; Elasticity; Income; Taxation; Policy
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Lockwood, Benjamin B., Afras Sial, and Matthew C. Weinzierl. "Designing, Not Checking, for Policy Robustness: An Example with Optimal Taxation." Tax Policy and the Economy 35 (2021).
  • 30 Sep 2013
  • Research & Ideas

Do Mergers Hurt Product Quality?

according to a recent study by Harvard Business School Assistant Professor Albert W. Sheen. In The Real Product Impact of Mergers, Sheen finds that mergers generally have little effect on product quality over time, even while product... View Details
Keywords: by Carmen Nobel; Consumer Products
  • 2011
  • Other Unpublished Work

Military Ties, New Ventures, and Political Risk Management in Emerging Economies

By: Shon R. Hiatt and Wesley Sine
New ventures in emerging economies face a number of challenges such as political instability, corruption, and uncertain property rights that can severely hinder their ability to grow and survive, yet little is known about how startups can mitigate such risk. Using data... View Details
Keywords: Risk Management; Business Startups; Government and Politics; Developing Countries and Economies; Latin America
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Hiatt, Shon R., and Wesley Sine. "Military Ties, New Ventures, and Political Risk Management in Emerging Economies." 2011.
  • July – August 2011
  • Article

What Factors Drive Analyst Forecasts?

By: Boris Groysberg, Paul Healy, Nitin Nohria and George Serafeim
A firm's competitive environment, its strategic choices, and its internal capabilities are considered important determinants of its future performance. Yet there is little evidence on whether analysts' forecasts of firm performance actually reflect any of these factors... View Details
Keywords: Competition; Forecasting and Prediction; Industry Growth; Judgments; Performance; Valuation; Price; Quality; Innovation and Invention; Organizational Culture; Competency and Skills; Surveys
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Groysberg, Boris, Paul Healy, Nitin Nohria, and George Serafeim. "What Factors Drive Analyst Forecasts?" Financial Analysts Journal 67, no. 4 (July–August 2011).
  • June 2010
  • Article

Leadership Competencies for Implementing Planned Organizational Change

By: Julie Battilana, Mattia Gilmartin, Anne-Claire Pache, Metin Sengul and Jeffrey A. Alexander
This paper bridges the leadership and organizational change literatures by exploring the relationship between managers' leadership competencies (namely, their effectiveness at person-oriented and task-oriented behaviors) and the likelihood that they will emphasize the... View Details
Keywords: Leadership; Competency and Skills; Organizational Change and Adaptation; Planning; Relationships; Business Processes; Projects; Theory; Change; Behavior; Health Industry; United Kingdom
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Battilana, Julie, Mattia Gilmartin, Anne-Claire Pache, Metin Sengul, and Jeffrey A. Alexander. "Leadership Competencies for Implementing Planned Organizational Change." Leadership Quarterly 21, no. 3 (June 2010).
  • October 2024
  • Article

Challenges and Facilitators in Implementing Remote Patient Monitoring Programs in Primary Care

By: Ruth Hailu, Jessica Sousa, Mitchell Tang, Ateev Mehrotra and Lori Uscher-Pines
Background: The COVID-19 pandemic resulted in greater use of remote patient monitoring (RPM). However, the use of RPM has been modest compared to other forms of telehealth.
Objective: To identify and describe barriers to the implementation of RPM among primary... View Details
Keywords: Health Care and Treatment; Technology Adoption; Health Industry
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Hailu, Ruth, Jessica Sousa, Mitchell Tang, Ateev Mehrotra, and Lori Uscher-Pines. "Challenges and Facilitators in Implementing Remote Patient Monitoring Programs in Primary Care." Journal of General Internal Medicine 39, no. 13 (October 2024): 2471–2477.
  • April 2025 (Revised May 2025)
  • Case

Adobe: GenAI Opportunity or Threat?

By: Sunil Gupta, Rajiv Lal and Allison Ciechanover
In December 2022, Adobe CEO Shantanu Narayen faced a pivotal strategic decision due to the rapid rise of generative AI image models from OpenAI, Midjourney, and StabilityAI. Adobe, a leader in digital media and marketing software with a 40-year legacy of innovation and... View Details
Keywords: Customer Relationship Management; Ethics; AI and Machine Learning; Trust; Business Strategy; Technology Industry; San Jose
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Gupta, Sunil, Rajiv Lal, and Allison Ciechanover. "Adobe: GenAI Opportunity or Threat?" Harvard Business School Case 525-052, April 2025. (Revised May 2025.)
  • Other Article

Want to See the Future of Digital Health Tools? Look to Germany

By: Ariel Dora Stern, Henrik Matthies, Julia Hagen, Jan B. Brönneke and Jörg F. Debatin
A new law will make it easier to introduce and determine the benefits of new tools. Perhaps its most important provisions are its formalization of “prescribable applications,” which include standard software, SaaS, and mobile as well as browser-based apps, and the... View Details
Keywords: Health Care and Treatment; Transformation; Internet and the Web; Technological Innovation; Germany
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Stern, Ariel Dora, Henrik Matthies, Julia Hagen, Jan B. Brönneke, and Jörg F. Debatin. "Want to See the Future of Digital Health Tools? Look to Germany." Harvard Business Review (website) (December 2, 2020).
  • October 2016
  • Article

Looking Across and Looking Beyond the Knowledge Frontier: Intellectual Distance and Resource Allocation in Science

By: Kevin J. Boudreau, Eva Guinan, Karim R. Lakhani and Christoph Riedl
Selecting among alternative innovative projects is a core management task in all innovating organizations. In this paper, we focus on the evaluation of frontier scientific research projects. We argue that the "intellectual distance" between the knowledge embodied in... View Details
Keywords: Knowledge; Innovation; Novelty; Evaluation; Resource Allocation; Decision Choices and Conditions; Innovation and Management; Science-Based Business; Experience and Expertise
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Boudreau, Kevin J., Eva Guinan, Karim R. Lakhani, and Christoph Riedl. "Looking Across and Looking Beyond the Knowledge Frontier: Intellectual Distance and Resource Allocation in Science." Management Science 62, no. 10 (October 2016).
  • 18 Nov 2010
  • Working Paper Summaries

Payout Taxes and the Allocation of Investment

Keywords: by Bo Becker, Marcus Jacob & Martin Jacob
  • 27 Oct 2010
  • Working Paper Summaries

Prosocial Spending and Well-Being: Cross-Cultural Evidence for a Psychological Universal

Keywords: by Lara B. Aknin, Elizabeth W. Dunn, Christopher P. Barrington-Leigh, John Helliwell, Robert Biswas-Diener, Imelda Kemeza, Paul Nyende, Claire Ashton-James & Michael I. Norton
  • August 2023
  • Article

Status and Mortality: Is There a Whitehall Effect in the United States?

By: Tom Nicholas
The influential Whitehall studies found that top-ranking civil servants in Britain experienced lower mortality than civil servants below them in the organizational hierarchy due to differential exposure to workplace stress. I test for a Whitehall effect in the United... View Details
Keywords: Mortality; Status; Working Conditions; Rank and Position; Welfare; Well-being; Health
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Nicholas, Tom. "Status and Mortality: Is There a Whitehall Effect in the United States?" Economic History Review 76, no. 3 (August 2023): 1191–1230.
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