Publications

2024
Working Paper

Chimeric Antigen Receptor T-Cell Therapy—Living Drugs: Case Histories of Transformational Advances

By: Amar Bhidé and Srikant M. Datar

In 2017, the US Food and Drug Administration (FDA) approved an immunotherapeutic treatment, called CAR-T therapy, for two kinds of blood cancers—acute leukemia (ALL) and a lymphoma. We describe 1) how CAR-T works, 2) the foundational advances and discoveries, 3) the... View Details

Keywords: Immunotherapy; Health Care and Treatment; Innovation and Invention; Research and Development; Governing Rules, Regulations, and Reforms

SSRN

28 Dec 2022
News

US Immigrants Generate 36 percent of Nation’s Innovation, Study Finds

November 2022
Case

Arcos Dorados’ Quest for the Digitalization of Last-Mile Delivery in Colombia

By: Jorge Tamayo, Jenyfeer Martinez Buitrago and Mariana Cal

In 2018, Francisco Staton, Managing Director of Arcos Dorados in Colombia had to decide on the company’s strategy to expand its food ordering and delivery business in the country. Arcos Dorados stood as McDonald’s largest independent franchisee, and Colombia was one of... View Details

November 2016 (Revised April 2018)
Case

reMarkable: e-Writing the Future

By: Elie Ofek and Curtis Hsu

Magnus Wanberg is the creator of reMarkable, a breakthrough e-writer device set apart from similar products on the market by having solved the frustrating “slow ink” problem typically experienced on pen-based electronic devices, thus providing a “pen and paper” like... View Details

Keywords: Entrepreneurial Marketing; Innovation Management; Go To Market Strategy; Marketing Plan; Target Market; Digital Devices; Consumer Electronics; Forecasting; Information Technology; Marketing Strategy; Innovation and Management; Marketing Channels; Entrepreneurship; Forecasting and Prediction; Product Marketing; Product Development; Electronics Industry

04 Aug 2023
Blog Post

Four Remarkable Stories of HBS MBA Students Tackling Climate Change

This article was originally published by MBAGRADSCHOOLS, a leading source of information for prospective MBA students. Climate change is not a problem for the future generation, it’s here and now. As the clock keeps ticking, HBS MBA... View Details

01 Dec 2000
News

Everything Old Is New Again: The History of Technological Frontiers

Amazon.com (zealously seeking government-issued patents for e-commerce innovations) and the trio of Netscape, Oracle, and Sun (bolstering the Justice Department's case against Microsoft). Historically, Spar observed, breakthrough View Details

Keywords: Laura Singleton; Microsoft; News, Library, Internet, and Other Services; Information; Broadcasting (except Internet); Information

Web

The Idea of Instant Photography - Edwin H. Land & Polaroid | Harvard Business School

developing. EXPLORE MORE OF THE EXHIBIT EXPLORE x HOME EMERGENCE OF A NEW TECHNOLOGY The Invention of the Polarizer A RESEARCH & MANUFACTURING COMPANY Commercialization View Details

Article

Creating Ecotourism in Costa Rica, 1970–2000

By: Geoffrey Jones and Andrew Spadafora

Between the 1970s and the 2000s, Costa Rica became established as the world’s leading ecotourism destination. This article argues that although Costa Rica benefited from biodiversity and a pleasant climate, the country’s preeminence in ecotourism requires more than a... View Details

Keywords: Ecotourism; Entrepreneurship In Emerging Markets; Sustainable Business And Innovation; Tourism; Green Business; Entrepreneurship; Growth and Development; History; Business History; Tourism Industry; Latin America; Costa Rica

Article

A Field Experiment on Search Costs and the Formation of Scientific Collaborations

By: Kevin Boudreau, Tom Brady, Ina Ganguli, Patrick Gaule, Eva C. Guinan, Anthony Hollenberg and Karim R. Lakhani

We present the results of a field experiment conducted at Harvard Medical School to understand the extent to which search costs affect matching among scientific collaborators. We generated exogenous variation in search costs for pairs of potential collaborators by... View Details

Keywords: Search Costs; Cost; Marketplace Matching; Groups and Teams; Science; Collaborative Innovation and Invention

2024
Working Paper

Moral Incoherence During Category Emergence: The Contentious Case of Connected Toys

By: Ryann Noe

Through a longitudinal study of the emergence of connected toys – physical toys that interact with digital devices – I build theory about moral incoherence: when competing views about the moral worth of a category persist over time. During the course of their... View Details

Keywords: Technological Innovation; Technology Adoption; Moral Sensibility; Market Entry and Exit; Consumer Behavior

June 2021
Case

Akira Fukabori and Kevin Kajitani at avatarin (A)

By: Linda A. Hill and Emily Tedards

In 2016, Akira Fukabori and Kevin Kajitani, aeronautical engineers at All Nippon Airways Co., Ltd., began to wonder why, in a world of accelerating globalization and digital connectivity, those who lived in far-remote villages or impoverished urban areas could not... View Details

Keywords: Agility; Ecosystem; Innovation Ecosystems; Crowdsourcing; Open Innovation; Partnership; Government; Collaboration; Co-creation; Purpose; Impact; Social Impact; Movement; Organizational Behavior; Organizational Ambidexterity; Ambidexterity; Culture; Culture Change; Global Teams; Experimentation; Space; Airline Industry; Start-up; Platform Business; Platform Strategy; Platform; Digital; Robotics; Robots; Mobility; Strategy; COVID-19; Intrapreneurship; Public-private Partnership; XPRIZE; Space Industry; Avatar; Telepresence; Innovation Lab; Innovation and Invention; Technological Innovation; Partners and Partnerships; Collaborative Innovation and Invention; Alignment; Leadership; Leading Change; Diversity; Organizational Culture; Change Management; Entrepreneurship; Digital Platforms; Transportation Industry; Aerospace Industry; Japan

20 Oct 2020
Blog Post

Changing the Face of Entrepreneurship and Venture Capital at Harlem Capital

Walking into Harvard Business School as friends, roommates, and colleagues in 2017, Henri Pierre-Jacques (MBA 2019) and Jarrid Tingle (MBA 2019) already knew each other well. What they didn’t know yet was how their angel syndicate, Harlem Capital, would grow, evolve,... View Details

Keywords: Entrepreneurship; Venture Capital / Private Equity

2018
Working Paper

Information Provision and Innovation: Natural Experiment of Herbal Patent Prior Art Adoption at the United States and European Patent Offices

By: Prithwiraj Choudhury and Tarun Khanna

We exploit a natural experiment to study how codifying information about prior innovation affects subsequent innovation. A codified database of traditional Indian herbal formulations was adopted by the European Patent Office (EPO) and the U.S. Patent and Trademark... View Details

Keywords: Patents; Plant-Based Agribusiness; Ethnicity; Health Care and Treatment; Pharmaceutical Industry; Agriculture and Agribusiness Industry; China; India

25 Mar 2019
News

New generation of startups threaten blue-chips like CVS and UnitedHealth

2004
Book

The Keystone Advantage: What the New Dynamics of Business Ecosystems Mean for Strategy, Innovation, and Sustainability

By: Marco Iansiti and Roy Levien

Keywords: Competitive Advantage; Strategy; Innovation and Invention

2011
Chapter

Reversing the Null: Regulation, Deregulation, and the Power of Ideas

By: David Moss

Keywords: Governing Rules, Regulations, and Reforms; Innovation and Invention; Government and Politics

1988
Chapter

Originality in Management Accounting Systems: Field Studies of the Processes

By: Robert S. Kaplan

Keywords: Accounting; Innovation and Management

January 2023 (Revised May 2023)
Case

Steve Jobs: Changing the World

By: Robert Simons and Shirley Sun

This case traces the life of Steve Jobs who throughout his career flaunted convention and chose an unusual path to success. The case describes how Jobs, as young man, acquired an appreciation for aesthetics and the liberal arts, but was also quick to recognize and... View Details

Keywords: Entrepreneurship; Technology; Business Startups; Personal Characteristics; Leadership Style; Innovation; Work-life Balance; Innovation Leadership; Power and Influence; Success; Information Technology Industry; United States