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- December 2022
- Article
The Contribution of Price Growth to Pharmaceutical Revenue Growth in the United States: Evidence from Medicines Sold in Retail Pharmacies
By: Pragya Kakani, Michael Chernew and Amitabh Chandra
Context: To what extent does pharmaceutical revenue growth depend on new medicines versus increasing prices for existing medicines? Moreover, does using list prices, as is commonly done, instead of prices net of confidential rebates offered by manufacturers, which are...
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Kakani, Pragya, Michael Chernew, and Amitabh Chandra. "The Contribution of Price Growth to Pharmaceutical Revenue Growth in the United States: Evidence from Medicines Sold in Retail Pharmacies." Journal of Health Politics, Policy and Law 47, no. 6 (December 2022): 629–648.
- Winter 2022
- Article
Vaccines and the COVID-19 Pandemic: Lessons from Failure and Success
By: Scott Duke Kominers and Alex Tabarrok
The losses from the global COVID-19 pandemic have been staggering—trillions in economic costs, on top of significant losses of life, health, and well-being. The world made significant and successful investments in vaccines to mitigate the pandemic, yet there were...
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Keywords:
COVID-19;
Vaccination;
Market Design;
Health Pandemics;
Loss;
Outcome or Result;
Opportunities;
Crisis Management
Kominers, Scott Duke, and Alex Tabarrok. "Vaccines and the COVID-19 Pandemic: Lessons from Failure and Success." Oxford Review of Economic Policy 38, no. 4 (Winter 2022): 719–741.
- November 2022 (Revised March 2024)
- Case
Replika AI: Monetizing a Chatbot
By: Julian De Freitas and Nicole Tempest Keller
In early 2018, Eugenia Kuyda, co-founder and CEO of San Francisco-based chatbot Replika AI, was deciding how to monetize the app she had built. Launched in 2017, Replika was a consumer AI “companion app” developed by a team of AI software engineers originally based in...
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Keywords:
Mental Health;
Subscriber Models;
TAM;
Monetization Strategy;
Marketing Strategy;
Product Marketing;
AI and Machine Learning;
Applications and Software;
Product Positioning;
Health Disorders;
Technology Industry
De Freitas, Julian, and Nicole Tempest Keller. "Replika AI: Monetizing a Chatbot." Harvard Business School Case 523-016, November 2022. (Revised March 2024.)
- November 2022
- Case
Ajax Health: A New Model for Medical Technology Innovation
By: Regina E. Herzlinger and Ben Creo
This case teaches key success factors for both startup and established MedTech firms. It examines how to structure a firm to maximize innovation and financial returns with organizational structures that better align the incentives for the different skill sets...
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Keywords:
Business Startups;
Success;
Innovation Strategy;
Mergers and Acquisitions;
Market Entry and Exit;
Financial Strategy;
Business Model;
Partners and Partnerships;
Entrepreneurship;
Private Equity;
Technology Industry;
Medical Devices and Supplies Industry
Herzlinger, Regina E., and Ben Creo. "Ajax Health: A New Model for Medical Technology Innovation." Harvard Business School Case 323-043, November 2022.
- November 2022
- Case
The Battle Among Channels for Marketing Pharmaceuticals: UpScript, Pharmacy Benefit Managers, and Direct-to-Consumer Sales
By: Regina E. Herzlinger and Tiffany Farrell
Can an online, direct-to-consumer pharmacy both improve the quality and speed of care for patients who need branded drugs and stabilize profits for pharmaceutical manufacturers? UpScript, after years spent achieving legal and regulatory compliance and simultaneous...
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Keywords:
DTC;
Internet and the Web;
Marketing Channels;
Customer Value and Value Chain;
Governing Rules, Regulations, and Reforms;
Competitive Strategy;
Service Delivery;
Growth and Development Strategy;
Health Industry;
Health Industry;
Health Industry
Herzlinger, Regina E., and Tiffany Farrell. "The Battle Among Channels for Marketing Pharmaceuticals: UpScript, Pharmacy Benefit Managers, and Direct-to-Consumer Sales." Harvard Business School Case 323-031, November 2022.
- November 2022 (Revised December 2022)
- Exercise
Choose Your Own Adventure: Your Financial Health (A): Congratulations, HBS Grad! Now, What?
By: Sara Fleiss and Emily R. McComb
Fleiss, Sara, and Emily R. McComb. "Choose Your Own Adventure: Your Financial Health (A): Congratulations, HBS Grad! Now, What?" Harvard Business School Exercise 223-043, November 2022. (Revised December 2022.)
- November 2022 (Revised April 2024)
- Case
Martine Rothblatt and United Therapeutics: A Series of Implausible Dreams
By: Debora L. Spar and Julia M. Comeau
In 1990, satellite expert and Sirius XM founder Martine Rothblatt was determined to save the life of her seven-year-old daughter, Jenesis, who was diagnosed with a terminal illness called Pulmonary Arterial Hypertension (PAH). At the time, there was little medication...
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Keywords:
Pharmaceutical Companies;
Technological And Scientific Innovation;
Organ Donation;
Health Care and Treatment;
Health Disorders;
Innovation and Invention;
Pharmaceutical Industry;
Medical Devices and Supplies Industry;
United States;
District of Columbia
Spar, Debora L., and Julia M. Comeau. "Martine Rothblatt and United Therapeutics: A Series of Implausible Dreams." Harvard Business School Case 323-039, November 2022. (Revised April 2024.)
- 2022
- Article
How Does Working from Home during COVID-19 Affect What Managers Do? Evidence from Time-Use Studies
By: Thomaz Teodorovicz, Raffaella Sadun, Andrew L. Kun and Orit Shaer
We assess how the sudden and widespread shift to working from home during the pandemic impacted how managers allocate time throughout their working day. We analyze the results from an online time-use survey with data on 1,192 knowledge workers (out of which 973 are...
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Keywords:
Time-use;
Working-from-home;
COVID;
Managers;
Knowledge Workers;
Health Pandemics;
Time Management
Teodorovicz, Thomaz, Raffaella Sadun, Andrew L. Kun, and Orit Shaer. "How Does Working from Home during COVID-19 Affect What Managers Do? Evidence from Time-Use Studies." Human-Computer Interaction 37, no. 6 (2022): 532–557.
- November 2022
- Article
Measuring Inequality beyond the Gini Coefficient May Clarify Conflicting Findings
By: Kristin Blesch, Oliver P. Hauser and Jon M. Jachimowicz
Prior research has found mixed results on how economic inequality is related to various outcomes. These contradicting findings may in part stem from a predominant focus on the Gini coefficient, which only narrowly captures inequality. Here, we conceptualize the...
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Keywords:
Economic Inequalty;
Gini Coefficient;
Income Inequality;
Equality and Inequality;
Social Issues;
Health;
Status and Position
Blesch, Kristin, Oliver P. Hauser, and Jon M. Jachimowicz. "Measuring Inequality beyond the Gini Coefficient May Clarify Conflicting Findings." Nature Human Behaviour 6, no. 11 (November 2022): 1525–1536.
- November 1, 2022
- Article
To Prepare for Future Surges, U.S. Hospitals Must Start Planning—& Sharing Resources—Now!
Keywords:
COVID-19;
Crisis Management;
Health Pandemics;
Disruption;
Planning;
Health Industry;
United States
Herzlinger, Regina E. "To Prepare for Future Surges, U.S. Hospitals Must Start Planning—& Sharing Resources—Now!" Medical Device News Magazine (November 1, 2022).
- October 2022
- Supplement
The SAH Group: The Time is Right, Instructor Spreadsheet
By: Juan Alcacer and Alpana Thapar
In January 2021, Jalila Mezni, CEO of the SAH Group, was preparing to present the company’s future growth plans to its board of directors. The Tunisian company was a leading producer and distributor of personal care and packaged hygiene products. In 2019, it expanded...
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- October 2022
- Supplement
The SAH Group: The Time is Right, Spreadsheet Supplement
By: Juan Alcacer and Alpana Thapar
In January 2021, Jalila Mezni, CEO of the SAH Group, was preparing to present the company’s future growth plans to its board of directors. The Tunisian company was a leading producer and distributor of personal care and packaged hygiene products. In 2019, it expanded...
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- October 2022
- Case
Lyra Health: Transforming Mental Health
By: Rembrand Koning and Nicole Keller
In January 2022, Lyra Health was deciding between several different alternatives to grow the business. Founded in 2015, Lyra Health, was a digital mental health platform that combined technology with human therapists and coaches to deliver high quality mental health...
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- October 2022
- Case
Afrigen Biologics: Vaccines for the Global South
By: Debora L. Spar and Julia Comeau
The majority of vaccines used on the continent of Africa (99%) are produced offshore. This makes African nations reliant on the West for major health care needs, a problem which was exacerbated by the COVID-19 pandemic. Afrigen Biologics (in partnership with the WHO)...
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Keywords:
Vaccination;
Vaccine;
mRNA;
COVID;
COVID-19;
Inequity;
Hub-and-spoke;
Health Care and Treatment;
Health Pandemics;
Production;
Social Issues;
Business and Government Relations;
South Africa;
Africa
Spar, Debora L., and Julia Comeau. "Afrigen Biologics: Vaccines for the Global South." Harvard Business School Case 323-030, October 2022.
- October 17, 2022
- Article
Relational Diversity in Social Portfolios Predicts Well-Being
By: Hanne K. Collins, Serena F. Hagerty, Jordi Quoidbach, Michael I. Norton and Alison Wood Brooks
We document a link between the relational diversity of one’s social portfolio—the richness and evenness of relationship types across one’s social interactions—and well-being. Across four distinct samples, respondents from the United States who completed a preregistered...
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Keywords:
Social Interaction;
Social Engagement;
Well-being;
Happiness;
Social and Collaborative Networks;
Family and Family Relationships
Collins, Hanne K., Serena F. Hagerty, Jordi Quoidbach, Michael I. Norton, and Alison Wood Brooks. "Relational Diversity in Social Portfolios Predicts Well-Being." Proceedings of the National Academy of Sciences 119, no. 43 (October 17, 2022).
- October 2022
- Case
Weapons of Self Destruction: Zak Pym Williams and the Cultivation of Mental Wellness
By: Lauren Cohen, Ronnie Stangler and Grace Headinger
Zak Pym Williams, mental health advocate, grappled with the question of how to create a proactive mental health family environment for his children. Having witnessed how mental health challenges such as addiction and depression had impacted the past four generations of...
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Keywords:
Family;
U.S.;
Mental Health;
Family Business;
Entertainment;
Values and Beliefs;
Ethics;
Leading Change;
Family and Family Relationships;
Well-being;
Social Issues;
Entertainment and Recreation Industry;
United States;
California
Cohen, Lauren, Ronnie Stangler, and Grace Headinger. "Weapons of Self Destruction: Zak Pym Williams and the Cultivation of Mental Wellness." Harvard Business School Case 223-033, October 2022.
- October 2022
- Background Note
Note on Cyberattacks and Regulatory Regimes
Describes common types of cyberattacks on enterprises and their costs, as well as the fragmentary regulatory regimes through which U.S. states and regulatory agencies at the start of 2021 attempted to encourage disclosure of cyberattacks and to pursue enforcement...
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Keywords:
Regulations;
Regulatory Agencies;
Cyberattacks;
Governance;
Corporate Disclosure;
Cybersecurity;
Health Industry;
Health Industry;
Health Industry;
Health Industry;
United States
Nagle, Frank, George A. Riedel, William R. Kerr, and David Lane. "Note on Cyberattacks and Regulatory Regimes." Harvard Business School Background Note 723-392, October 2022.
- October 2022 (Revised September 2024)
- Case
mPharma: Scaling Access to Affordable Primary Care in Africa
By: Regina E. Herzlinger and Ben Creo
mPharma hopes to scale up to create the largest pan-African healthcare company ever to provide much-needed primary care in retail pharmacies; a reliable, fairly priced supply of drugs; and micro-insurance for drugs. They must prioritize launching a telemedicine...
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Keywords:
Africa;
Pharmaceutical Companies;
Pharmacy Benefit Manager;
Health Care;
Health Care And Treatment;
Health Care Costs;
Health Care Delivery;
Health Care Entrepreneurship;
Telehealth;
Health Equity;
Corporate Strategy;
Social Entrepreneurship;
Equity;
Growth and Development Strategy;
Expansion;
Product Launch;
Customer Value and Value Chain;
Social Enterprise;
Multinational Firms and Management;
Health Industry;
Health Industry;
Africa
Herzlinger, Regina E., and Ben Creo. "mPharma: Scaling Access to Affordable Primary Care in Africa." Harvard Business School Case 323-033, October 2022. (Revised September 2024.)
- June 2022
- Article
A New Initiative to Track HIV Resource Allocation and Costs
By: Ryan McBain, AK Nandakumar, Michael Ruffner, Carlyn Mann, Mai Hijazi, Susanna Baker, Linden Morrison, Kalipso Chalkidou, Shufang Zhang, Iris Semini, Fern Terris-Prestholt, Steven Forsythe, Sarah Byakika, Joshua Musinguzi and Robert S. Kaplan
In early 2020, several global health institutions – including the Global Fund to Fight AIDS, Tuberculosis and Malaria; Joint United Nations Program on HIV/AIDS (UNAIDS); United States Agency for International Development; and Office of the Global AIDS Coordinator at...
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Keywords:
Activity Based Costing;
HIV;
Cost;
Health Care;
Healthcare;
Health Care and Treatment;
Activity Based Costing and Management;
Resource Allocation;
Health Industry;
Africa
McBain, Ryan, AK Nandakumar, Michael Ruffner, Carlyn Mann, Mai Hijazi, Susanna Baker, Linden Morrison, Kalipso Chalkidou, Shufang Zhang, Iris Semini, Fern Terris-Prestholt, Steven Forsythe, Sarah Byakika, Joshua Musinguzi, and Robert S. Kaplan. "A New Initiative to Track HIV Resource Allocation and Costs." Bulletin of the World Health Organization 100, no. 6 (June 2022): 358–358A.
- September–October 2022
- Article
Case Study: What's the Right Career Move After a Public Failure?
By: Jon M. Jachimowicz and Francesca Gino
“Reunions are for happy people,” Mariani Kallis said to her friend Whitney on the phone. “I’m not going.” “Come on, it won’t be the same without you,” Whitney pleaded. “Besides, no one is happy right now. Everyone’s life is a mess.”
“I’m pretty sure none of our...
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Jachimowicz, Jon M., and Francesca Gino. "Case Study: What's the Right Career Move After a Public Failure?" Harvard Business Review 100, no. 5 (September–October 2022): 144–149.