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  • 05 Sep 2023
  • Book

Failing Well: How Your ‘Intelligent Failure’ Unlocks Your Full Potential

In the 1990s, after drugmaker Eli Lilly spent more than a decade and millions of dollars developing the new drug Alimta to treat lung cancer, the medication came up short in effectively treating cancer in... View Details
Keywords: by Michael Blanding
  • Article

DEA Model with Shared Resources and Efficiency Decomposition

By: Yao Chen, Juan Du, H. David Sherman and Joe Zhu
Data envelopment analysis (DEA) has proved to be an excellent approach for measuring performance of decision making units (DMUs) that use multiple inputs to generate multiple outputs. In many real world scenarios, DMUs have a two-stage network process with shared input... View Details
Keywords: Data Envelopment Analysis (DEA); Efficiency; Intermediate Measure; Performance Efficiency
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  • January 2007 (Revised August 2008)
  • Case

NatuRi Corporation

By: Robert F. Higgins and Virginia Fuller
NatuRi Corporation was a start up, founded in 2005, aiming to manufacture a cholesterol-lowering drug made from the byproducts of rice bran oil production. With operations split between Chennai, India and Boston, Massachusetts, NatuRi faced several challenges,... View Details
Keywords: Business Startups; Decision Choices and Conditions; Entrepreneurship; Venture Capital; Equity; Investment Funds; Growth and Development Strategy; Chennai; Boston
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  • Research Summary

Overview

ECONOMICS OF THE ADVERTISING AND MARKETING SERVICEC INDUSTRY

Professor Silk’s recent research has been focused on the economics of the advertising and marketing services industry. He has conducted econometric studies of the effects of scale and scope on the... View Details

  • 15 Jan 2018
  • Research & Ideas

A Better Business Model for Fighting Cancer

iPhoto With billions of dollars spent on the development of precision medicine and related cancer research over the last decade, a recent partnership seeks a new way to bring these treatments to patients more quickly: through a better... View Details
Keywords: by Julia Hanna; Health; Pharmaceutical
  • May 2012 (Revised August 2014)
  • Case

McKesson

By: Regina E. Herzlinger and Natalie Kindred
McKesson, a large, diversified drug distribution and health care IT company, is considering development of new business offerings to help private practice physicians remain independent. The company, with $122 billion in 2010 revenues, just made its first foray into... View Details
Keywords: Health Care Industry; Health Care Policy; Organizational Transformations; Health Services; Health Care and Treatment; Business Model; Service Operations; Change Management; Corporate Strategy; Information Technology; Policy; Pharmaceutical Industry; Health Industry; United States
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  • April 2009 (Revised May 2010)
  • Case

Partners In Health: HIV Care in Rwanda

By: Michael E. Porter, Scott S. Lee, Joseph Rhatigan and Jim Yong Kim
In 2005, Partners in Health (PIH) was invited by the Rwandan Ministry of Health to assume responsibility for the management of public health care in two rural districts in Eastern Rwanda and create an HIV treatment program at these sites. PIH successfully implemented a... View Details
Keywords: Developing Countries and Economies; Health Care and Treatment; Health Testing and Trials; Medical Specialties; Service Delivery; Nonprofit Organizations; Expansion; Health Industry; Rwanda
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  • Research Summary

Overview

By: Joshua Lev Krieger
In examining the competitive dynamics of R&D strategy, Josh has become particularly interested in how the introduction of new knowledge generated by rivals impacts the direction of R&D efforts. Understanding how new information alters project portfolio decisions is... View Details
  • 23 Mar 2020
  • Research & Ideas

Product Disasters Can Be Fertile Ground for Innovation

including a 20-article investigative series in the New York Times that discovered similar cases at other hospitals. The US Food and Drug Administration (FDA) started investigations of the CT devices, dozens of patients joined in a... View Details
Keywords: by Michael Blanding; Health; Medical Devices & Supplies
  • 23 Sep 2008
  • First Look

First Look: September 23, 2008

presided over the development of the empirical social sciences to address questions of labor regulation and control within manufacturing industries. Next, we look at the creation of the Carnegie Tech Graduate School of Industrial... View Details
Keywords: Martha Lagace
  • Research Summary

Clinical Trials as a setting for Health Policy and Management Research

The clinical trial marketplace is in flux. A decade ago, pharmaceutical firms almost exclusively conducted the study of their novel drug compounds within major academic medical centers. But today, industry-sponsored clinical trials are increasingly using community... View Details
  • 21 Feb 2018
  • Research & Ideas

When a Competitor Abandons the Market, Should You Advance or Retreat?

different markets but using the same technology. Among the findings: Companies were more than twice as likely to end development on a drug if a competitor in the same market using the same technology decided... View Details
Keywords: by Rachel Layne; Pharmaceutical; Health
  • 05 Dec 2017
  • First Look

First Look at New Research and Ideas, December 5, 2017

learning from parallel R&D projects in the setting of drug development. Leveraging the biopharmaceutical industry's unique characteristics to overcome barriers to measuring the project-level response to competitor news, I employ a... View Details
Keywords: Sean Silverthorne
  • 08 Aug 2011
  • Research & Ideas

The Death of the Global Manager

and its efforts to establish Humanitarian Assistance for Neglected Diseases (HAND), a corporate social responsibility program focused on treatments for diseases that typically affect too small a population to warrant the attention of drug... View Details
Keywords: by Julia Hanna
  • 25 Jul 2023
  • Research & Ideas

Could a Business Model Help Big Pharma Save Lives and Profit?

With Hepatitis C running rampant in Egypt in 2012, Clifford Samuel, then of California-based Gilead Sciences, convened a series of urgent meetings with Egyptian government officials, doctors, and patients. His goal? To make Gilead’s lifesaving Hepatitis C View Details
Keywords: by Esther Schrader; Pharmaceutical; Health
  • 16 Dec 2014
  • First Look

First Look: December 16

more or less effective. We develop these ideas in a multi-method study of a hospital emergency department (ED) redesign. Before the redesign, people coordinated in ad-hoc groupings, which provided flexibility because any nurse could work... View Details
Keywords: Sean Silverthorne
  • 27 Jan 2003
  • Research & Ideas

New Cluster Mapping Project Helps Companies Locate Facilities

economic development decisions to a new level of sophistication. In a cluster, a company can draw on a local supplier base of skilled people, specialized service providers, and local institutions that can provide training and perform... View Details
Keywords: by Sean Silverthorne
  • 23 Mar 2010
  • First Look

First Look: March 23

Publications "From Visible Harm to Relative Risk: Centralization and Fragmentation of Pharmacovigilance Author: Arthur A. Daemmrich Publication: Chap. 13 in The Fragmentation of U.S. Health Care, Oxford University Press, 2010 Abstract Adverse View Details
Keywords: Martha Lagace
  • 15 Nov 2022
  • Book

Stop Ignoring Bad Behavior: 6 Tips for Better Ethics at Work

In 1995, Purdue Pharma began selling a powerful and addictive opioid drug called OxyContin. The company was aware that the drug, which was marketed to doctors as a safe way to manage chronic pain, was a potent narcotic that could quickly... View Details
Keywords: by Pamela Reynolds
  • 09 Aug 2016
  • First Look

August 9, 2016

https://www.hbs.edu/faculty/Pages/item.aspx?num=51304 The Impact of the Entry of Biosimilars: Evidence from Europe By: Scott Morton, Fiona, Ariel Dora Stern, and Scott Stern Abstract—Biologic drugs (therapeutic proteins or... View Details
Keywords: Sean Silverthorne

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