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- 04 Sep 2019
- News
Accelerating Scientific Discovery
Amitabh Chandra, Henry and Allison McCance Professor of Business Administration at HBS and Ethel Zimmerman Wiener Professor of Public Policy and Director of Health Policy Research at HKS (photo by Susan Young) A key challenge in the life...
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Keywords:
Jennifer Gillespie
- Article
Measuring the Scientific Effectiveness of Contact Tracing: Evidence from a Natural Experiment
By: Thiemo Fetzer and Thomas Graeber
Contact tracing has for decades been a cornerstone of the public health approach to epidemics, including Ebola, severe acute respiratory syndrome, and now COVID-19. It has not yet been possible, however, to causally assess the method’s effectiveness using a randomized...
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Fetzer, Thiemo, and Thomas Graeber. "Measuring the Scientific Effectiveness of Contact Tracing: Evidence from a Natural Experiment." Proceedings of the National Academy of Sciences 118, no. 33 (August 17, 2021): 1–4.
- November 9, 2019
- Article
Effect of Revealing Authors' Conflicts of Interests in Peer Review: Randomized Controlled Trial
By: Leslie K. John, George Loewenstein, Andrew Marder and Michael Callaham
Objective: To assess the impact of disclosing authors’ conflict of interest declarations to peer reviewers at a medical journal.
Design: Randomised controlled trial.
Setting: The study was conducted within the manuscript review process at the... View Details
Design: Randomised controlled trial.
Setting: The study was conducted within the manuscript review process at the... View Details
Keywords:
Conflicts Of Interest;
Peer Review;
Randomized Controlled Trial;
Scientific Publication;
Conflict of Interests;
Journals and Magazines;
Science
John, Leslie K., George Loewenstein, Andrew Marder, and Michael Callaham. "Effect of Revealing Authors' Conflicts of Interests in Peer Review: Randomized Controlled Trial." BMJ: British Medical Journal 367, no. 8221 (November 9, 2019).
- 15 Nov 2018
- Book
Can the Global Food Industry Overcome Public Distrust?
JamesBrey Food is the largest segment of the global economy. It is also widely recognized as more critical for human health than any pharmaceutical drug on the planet. But significant changes in the industry are making people lose trust in many institutions involved in...
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- March 1, 2022
- Article
Widespread Use of National Academies Consensus Reports by the American Public
By: Diana Hicks, Matteo Zullo, Ameet Doshi and Omar Isaac Asensio
In seeking to understand how to protect the public information sphere from corruption, researchers understandably focus on dysfunction. However, parts of the public information ecosystem function very well, and understanding this as well will help in protecting and...
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Keywords:
Reports;
Surveys;
AI and Machine Learning;
Knowledge Dissemination;
Knowledge Use and Leverage
Hicks, Diana, Matteo Zullo, Ameet Doshi, and Omar Isaac Asensio. "Widespread Use of National Academies Consensus Reports by the American Public." e2107760119. Proceedings of the National Academy of Sciences 119, no. 9 (March 1, 2022).
- April 5, 2023
- Article
We Need an Operation Warp Speed for Long COVID
By: Esther K. Choo and Scott Duke Kominers
With millions of people affected and at least $1 trillion of economic value at stake, long COVID is our next national health emergency.
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Keywords:
COVID;
COVID-19;
COVID-19 Pandemic;
Scientific Research;
Policy;
Health Policy;
Innovation;
Science;
Public Finance;
Public Health;
Health Disorders;
Health Care and Treatment;
Human Capital
Choo, Esther K., and Scott Duke Kominers. "We Need an Operation Warp Speed for Long COVID." Scientific American (website) (April 5, 2023).
- Forthcoming
- Article
How Important Is Editorial Gatekeeping? Evidence from Top Biomedical Journals
By: Joshua L. Krieger, Kyle R. Myers and Ariel D. Stern
We examine editors' influence on the scientific content of academic journals by unpacking the role of three major forces: journals' missions, aggregate supply of and demand for specific topics, and scientific homophily via editorial gatekeeping. In a sample of top...
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Keywords:
Editors;
Biomedical Research;
Editorial Gatekeeping;
Scientific Homophily;
Intellectual Capital;
Mission and Purpose;
Journals and Magazines;
Intellectual Property;
Innovation and Invention;
Human Capital;
Higher Education;
Publishing Industry
Krieger, Joshua L., Kyle R. Myers, and Ariel D. Stern. "How Important Is Editorial Gatekeeping? Evidence from Top Biomedical Journals." Review of Economics and Statistics (forthcoming). (Pre-published online May 29, 2023.)
- 2015
- Working Paper
Public R&D Investments and Private-sector Patenting: Evidence from NIH Funding Rules
By: Pierre Azoulay, Joshua S. Graff Zivin, Danielle Li and Bhaven N. Sampat
We quantify the impact of scientific grant funding at the National Institutes of Health (NIH) on patenting by pharmaceutical and biotechnology firms. Our paper makes two contributions. First, we use newly constructed bibliometric data to develop a method for flexibly...
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Keywords:
Economics Of Science;
Patenting;
Academic Reserach;
NIH;
Knowledge Spillovers;
Patents;
Research;
Government and Politics
Azoulay, Pierre, Joshua S. Graff Zivin, Danielle Li, and Bhaven N. Sampat. "Public R&D Investments and Private-sector Patenting: Evidence from NIH Funding Rules." Harvard Business School Working Paper, No. 16-056, October 2015.
- 02 Sep 2014
- Research & Ideas
Food Stamp Entrepreneurs: How Public Assistance Enables Business Bootstrapping
startup funds—and what allowed them to take the risk of launching a company." Curiosity eventually led to his doctoral dissertation: a series of studies showing a definitive link between the social safety net and entrepreneurship. In short, Olds finds that an...
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- 2016
- Article
Academia's Emerging Crisis of Relevance and the Consequent Role of the Engaged Scholar
By: Andrew J. Hoffman
Universities are facing a crisis of relevance. While there are multiple reasons for this to be happening, one that deserves particular attention is the extent to which academic scholars do not see it as their role to engage in public and political discourse. However,...
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Hoffman, Andrew J. "Academia's Emerging Crisis of Relevance and the Consequent Role of the Engaged Scholar." Journal of Change Management 16, no. 2 (2016): 77–96.
- August 2020
- Article
A History of Prescription Drug Monitoring Programs in the United States: Political Appeal and Public Health Efficacy
By: A Jay Holmgren, Alyssa Botelho and Allan M Brandt
Prescription drug monitoring programs (PDMPs) have become a widely embraced policy to address the US opioid crisis. Despite mixed scientific evidence on their effectiveness at improving health and reducing overdose deaths, 49 states and Washington, DC have adopted...
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Keywords:
Health Disorders;
Information Technology;
Programs;
Technology Adoption;
History;
Government and Politics;
Policy;
United States
Holmgren, A Jay, Alyssa Botelho, and Allan M Brandt. "A History of Prescription Drug Monitoring Programs in the United States: Political Appeal and Public Health Efficacy." American Journal of Public Health 110, no. 8 (August 2020).
- 01 Jun 2004
- News
Merck’s Gilmartin on Vaccines, Global Health
that policymakers concerned with global public health must pay “dramatically greater” attention to vaccine-related issues. He pointed out that 3 million children worldwide die each year from diseases for which vaccines already exist. Even...
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- 23 Aug 2020
- News
In the UK, She Leads the Search for a COVID Vaccine
Kate Bingham (MBA 1991) Kate Bingham (MBA 1991) When she was asked to chair the UK’s Vaccine Taskforce back in May, Kate Bingham (MBA 1991) paused. Despite nearly three decades of experience as a life sciences investor with SV Health Investors, the enormity of leading...
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- 2015
- Book
How Culture Shapes the Climate Change Debate
By: Andrew J. Hoffman
Though the scientific community largely agrees that climate change is underway, debates about this issue remain fiercely polarized. These conversations have become a rhetorical contest, one where opposing sides try to achieve victory through playing on fear, distrust,...
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Hoffman, Andrew J. How Culture Shapes the Climate Change Debate. Stanford University Press, 2015. (Winner of the 2019 Responsible Research in Business Management Award; Honorable Mention for the 2016 Best Book Award, Organizations and Natural Environment Division, Academy of Management. Czech Edition: Jak kultura utváří diskusi o klimatické změně, Muni Press, 2017.)
- May 2008 (Revised May 2008)
- Case
Symyx Technologies, Inc.
By: H. Kent Bowen, Courtney Purrington and Thomas D. Perry
Symyx is a science-based company spun out of Berkeley. Its unique materials technology has been exploited for 10 years, but the company needs a new business model. The company concept required the invention of hardware and software to do high throughput materials...
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Keywords:
Business Model;
Transition;
Engineering;
Technological Innovation;
Resource Allocation;
Product Development;
Partners and Partnerships;
Science-Based Business;
Information Infrastructure;
Applications and Software
Bowen, H. Kent, Courtney Purrington, and Thomas D. Perry. "Symyx Technologies, Inc." Harvard Business School Case 608-152, May 2008. (Revised May 2008.)
- Forthcoming
- Article
Standing on the Shoulders of Science
By: Joshua Lev Krieger, Monika Schnitzer and Martin Watzinger
Today’s innovations rely on scientific discoveries of the past, yet only some corporate
R&D builds directly on scientific output. In this paper, we analyze U.S. patents to
investigate how firms generate value by building on prior art “closer” to science. We
show...
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Krieger, Joshua Lev, Monika Schnitzer, and Martin Watzinger. "Standing on the Shoulders of Science." Strategic Management Journal (forthcoming). (Pre-published online March 25, 2024.)
- 23 Mar 2012
- HBS Seminar
Dan Kahan, Professor of Law and Professor of Psychology at Yale Law School
- 2010
- Working Paper
Boundary Spanning in a For-profit Research Lab: An Exploration of the Interface Between Commerce and Academe
By: Christopher C. Liu and Toby E. Stuart
In innovative industries, private-sector companies increasingly are participants in open communities of science and technology. To participate in the system of exchange in such communities, firms often publicly disclose what would otherwise remain private discoveries....
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Keywords:
For-Profit Firms;
Higher Education;
Information Publishing;
Innovation and Invention;
Science-Based Business;
Social and Collaborative Networks;
Boundaries;
Biotechnology Industry;
Pharmaceutical Industry
Liu, Christopher C., and Toby E. Stuart. "Boundary Spanning in a For-profit Research Lab: An Exploration of the Interface Between Commerce and Academe." Harvard Business School Working Paper, No. 11-012, August 2010.
- January–February 2021
- Article
Food and Drug Administration Guidance Documents and New Medical Devices: The Case of Breast Prostheses
By: Rachel E. Weitzman, Ariel Dora Stern and Daniel B. Kramer
As pressure mounts on the Food and Drug Administration (FDA) to speed its review process for novel devices, and budgetary pressures further strain its resources, the critical role of guidance documents in assuring consistent, rigorous, and scientifically grounded...
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Keywords:
Medical Devices;
FDA;
Health Care and Treatment;
Government Administration;
Information;
Standards
Weitzman, Rachel E., Ariel Dora Stern, and Daniel B. Kramer. "Food and Drug Administration Guidance Documents and New Medical Devices: The Case of Breast Prostheses." American Journal of Therapeutics 28, no. 1 (January–February 2021).
- November 2001 (Revised September 2004)
- Case
Evolution of Treatment, The: The Case of Diabetes
By: Richard M.J. Bohmer, Jeffrey D. Street and Laura Feldman
Scientific knowledge surrounding diabetes mellitus has grown over the last century to include its cause, treatment, and prevention strategies. However, the type and level of care that patients receive is suboptional. This case examines the forces in industry,...
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Keywords:
Policy;
Health Care and Treatment;
Innovation and Management;
Knowledge Use and Leverage;
Management;
Management Analysis, Tools, and Techniques;
Health Industry
Bohmer, Richard M.J., Jeffrey D. Street, and Laura Feldman. "Evolution of Treatment, The: The Case of Diabetes." Harvard Business School Case 302-023, November 2001. (Revised September 2004.)