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  • 2024
  • Working Paper

Coronary Artery Bypass Grafting—Impossible to Routine: Case Histories of Transformational Advances

By: Amar Bhidé, Srikant M. Datar and Fabio Villa
We describe how Coronary Artery Bypass Grafting (CABG, or more popularly, “bypass”) operations revolutionized the treatment of coronary disease (that can produce fatal heart attacks and debilitating angina). Specifically, we chronicle the: 1) development of the... View Details
Keywords: Health Care and Treatment; Technological Innovation; Innovation Strategy; Technology Adoption; Collaborative Innovation and Invention; Innovation and Invention; Governing Rules, Regulations, and Reforms
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  • March 2015 (Revised February 2022)
  • Supplement

CV Ingenuity (B): Epilogue

By: Regina E. Herzlinger and Andrew Otazo
Duke Rohlen used a lea-nfunding, iconoclastic strategy for his start up for a drug eluding balloon for peripheral artery disease. His giant competitors were first movers. Did Duke obtain the funding he sought? How did his DEB fare versus that of his competitors? The... View Details
Keywords: CV Ingenuity; CVI; Drug Eluting Balloon; DEB; Drug Eluting Stent; Angioplasty Balloon; FoxHollow; Medical Device; Medical Device Startup; Premarket Approval; PMA; Lutonix; Stellarex; LEVANT; ILLUMENATE; Clinical Trials; Peripheral Arterial Disease; PAD; Healthcare Startups; Covidien; Health Care and Treatment; Health Testing and Trials; Business Startups; Commercialization; Strategy; Health Industry; Medical Devices and Supplies Industry; United States; Europe
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  • Article

Time-driven Activity-based Costing of Multivessel Coronary Artery Bypass Grafting across National Boundaries to Identify Improvement Opportunities: Study Protocol

By: F. Erhun, B. Mistry, T. Platcheck, A. Milstein, V.G. Narayanan and R. S. Kaplan
Coronary artery bypass graft (CABG) surgery is a common treatment for coronary artery disease—a disease that affects over 10% of US adults and is a major cause of morbidity and mortality. In 2005, the mean cost for a CABG procedure among Medicare beneficiaries in the... View Details
Keywords: Activity Based Costing and Management; Health Disorders; Health Care and Treatment; United States; India
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  • March 2015 (Revised January 2024)
  • Case

CV Ingenuity (A): How to Evaluate the Commercial Viability of New Health Care Technologies

By: Regina E. Herzlinger and Andrew Otazo
Duke Rohlen (HBS MBA ’01) hoped to win over a prominent venture capital investor for Series B financing of his firm CVI that was creating a drug-eluting balloon (DES) to treat peripheral arterial disease. As a second-mover, Duke felt he was more likely to acquire... View Details
Keywords: CV Ingenuity; CVI; Drug Eluting Balloon; DEB; Drug Eluting Stent; Angioplasty Balloon; FoxHollow; Medical Device; Medical Device Startup; Premarket Approval; PMA; Lutonix; Stellarex; LEVANT; ILLUMENATE; Clinical Trials; Peripheral Arterial Disease; PAD; Healthcare Startups; Covidien; Health Care and Treatment; Health Testing and Trials; Business Startups; Commercialization; Health Industry; Medical Devices and Supplies Industry; United States; Europe
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  • 19 Jun 2013
  • News

US accountable care organisations: factory-style focus calls for change in behaviour

  • 09 May 2017
  • First Look

New Research and Ideas, May 9

to dealers with whom they have the strongest ties, and more so during periods of market turmoil. Systemically important dealers exploit their connections at the expense of peripheral dealers as well as clients, charging higher markups... View Details
Keywords: Sean Silverthorne
  • Web

Organize Care Around Medical Conditions - Institute For Strategy And Competitiveness

represents either an acute or chronic disease process that may require management by multiple clinicians representing different specialties and types of providers and support personnel. Care for a medical condition involves management of... View Details
  • Web

ICHOM - Institute For Strategy And Competitiveness

Consortium for Health Outcomes Measurement (ICHOM) works with patients, leading providers, and registries to create a global standard for measuring results by medical condition, from prostate cancer to coronary artery disease. ICHOM... View Details
  • 20 Dec 2010
  • Research & Ideas

Panama Canal: Troubled History, Astounding Turnaround

relationship that many scholars have claimed could greatly improve governance in many third world nations: the United States ran the currency, provided aid, posted an official inside the Panamanian government, and operated one of the great commercial View Details
Keywords: by Sarah Jane Gilbert; Transportation
  • 01 Mar 2005
  • News

Better Care at Lower Cost

good example of disruptive innovation, Christensen noted. Before the development of balloon angioplasty, patients with coronary artery disease had to be seriously ill before getting open-heart bypass... View Details
Keywords: Colleges, Universities, and Professional Schools; Educational Services; Health, Social Assistance
  • 01 Dec 2013
  • News

To Market, to Market

Inhibitors of proteins that play an important role in cholesterol and fat metabolism, to be developed as potential therapeutics for the treatment of diseases such as metabolic syndrome, type 2 diabetes, coronary View Details
Keywords: Scientific Research and Development Services
  • 03 Dec 2001
  • Research & Ideas

Healthcare Conference Looks At Ailing Industry

he said, patients had to be "almost dead" before they could be treated for coronary artery disease with open-heart bypass surgery. The surgery was only available at select academic medical centers... View Details
Keywords: by Martha Lagace; Health
  • 09 Mar 2009
  • Research & Ideas

How to Revive Health-Care Innovation

effective solution. In the past, business model innovation was common in health care. When the technological enablers for the diagnosis and treatment of infectious diseases emerged, most patient care was transferred away from hospitals to... View Details
Keywords: by Clayton M. Christensen, Jerome H. Grossman, M.D. M.D. & Jason Hwang; Health
  • 13 Jun 2005
  • Research & Ideas

From Turf Wars to Learning Curves: How Hospitals Adopt New Technology

hospitals. In the March 3, 2005, story Turf Wars in Coronary Revascularization, Pisano and Huckman looked at competing treatment methods for coronary artery disease and discovered a tough battleground... View Details
Keywords: by Sara Grant; Health