Gene Editing - Publications - Faculty & Research - Harvard Business School

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September–October 2020
Article

The Past, Present, and (Near) Future of Gene Therapy and Gene Editing

By: Julia Pian, Amitabh Chandra and Ariel Dora Stern

Emerging gene therapy and gene-editing technologies will have a growing impact on patient lives and health-care delivery. We analyzed a decade of data on clinical trials and venture capital investments to understand the likely trajectory of genetically focused... View Details

Keywords: Gene Therapy; Gene Editing; Impact; Health Care and Treatment; Technological Innovation; Health Testing and Trials; Venture Capital; Change

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January 2024 (Revised April 2024)
Case

Target Malaria: Editing Mosquitoes through Gene Drives

By: Shikhar Ghosh and Shweta Bagai

Target Malaria, a non-profit research consortium, is exploring the application of CRISPR-Cas9 gene editing technology to combat malaria in Sub-Saharan Africa. Its approach uses gene drives, a revolutionary tool, to suppress the population of malaria-carrying... View Details

Keywords: Health Disorders; Technological Innovation; Nonprofit Organizations; Business Strategy; Genetics; Ethics; Governing Rules, Regulations, and Reforms; United States; United Kingdom; Burkina Faso; Africa

December 2021
Case

Pairwise

By: José B. Alvarez and Annelena Lobb

Pairwise discusses the strategic approach of a company aiming to “snackify” fruits and vegetables by using CRISPR-Cas9 gene editing to create nutritious, bite-sized foods that could compete with packaged snacks. The company is confronting a number of challenges,... View Details

Keywords: Gene Editing; GMO; Food; Nutrition; Competition; Market Entry and Exit; Public Opinion; Competitive Strategy; Consumer Behavior; Food and Beverage Industry

June 2023
Case

Verve Therapeutics: Taking DNA Editing to Heart

By: Shikhar Ghosh and Shweta Bagai

Verve Therapeutics, a public biotech company based in Boston, created a novel approach to addressing cardiovascular disease (CVD) - a leading cause of deaths globally. The company's approach was a single shot treatment to permanently lower cholesterol, thus reducing... View Details

Keywords: AI; Genetic Engineering; Medicine; Health Care and Treatment; Genetics; Innovation Strategy; Business and Stakeholder Relations; Medical Specialties; Innovation and Invention; Entrepreneurship; Biotechnology Industry

October 2016 (Revised September 2017)
Case

The CRISPR-Cas9 Quarrel

By: Richard G. Hamermesh and Matthew G. Preble

In mid-2016, the Broad Institute and the University of California, Berkeley were in the middle of a contentious patent dispute over which entity controlled a breakthrough gene editing technology called CRISPR-Cas9. With CRISPR-Cas9, scientists might soon be able to... View Details

Keywords: CRISPR; Broad Institute; University Of California Berkeley; Intellectual Property; Patents; Law; Lawsuits and Litigation; Science; Genetics; Entrepreneurship; Biotechnology Industry; United States

20 Oct 2003
Research & Ideas

Gaps in the Historical Record: Development of the Electronics Industry

In a recently published book on current international research in business history, edited by Harvard Business School professor Geoffrey Jones, HBS professor emeritus Alfred D. Chandler Jr. contributed an essay on the opportunities... View Details

Keywords: by Alfred D. Chandler Jr.; Consumer Products

10 May 2017
Research & Ideas

Amazon Web Services Changed the Way VCs Fund Startups

hopes to address this question in future research. On the bright side, he says, technological innovations have come so quickly in recent years that there are few industry sectors that have not seen their development costs dramatically decrease. For example, CRISPR... View Details

Keywords: by Michael Blanding; Banking; Financial Services; Information Technology

14 Jul 2009
First Look

First Look: July 14

Backlash Against Investment Arbitration, edited by Michael Waibel, Asha Kaushal, Kyo-Hwa Chung, and Claire Balchin. London: Wolters Kluwer Law & Business, forthcoming Abstract There are at least three reasons for the current backlash... View Details

Keywords: Martha Lagace

22 Nov 2016
First Look

November 22, 2016

and the University of California, Berkeley were in the middle of a contentious patent dispute over which entity controlled a breakthrough gene editing technology called CRISPR-Cas9. With CRISPR-Cas9,... View Details

Keywords: Sean Silverthorne

15 Jul 2008
First Look

First Look: July 15, 2008

and Rohini Somanathan Publication:In Handbook of Development Economics. Vol. 4, edited by T. Paul Schultz and John Strauss. Elsevier Science & Technology Books, 2008 Abstract This chapter focuses on the relationship between public... View Details

Keywords: Martha Lagace

13 Jan 2009
First Look

First Look: January 13, 2009

Should this gene detection firm enter the business of providing tests for the detection of genetic diseases? If so, how should it prioritize the tests it could develop? Purchase this case: http://harvardbusinessonline.hbsp.harvard.edu/... View Details

Keywords: Martha Lagace

30 Mar 2010
First Look

First Look: March 30

Read the preview: http://hbr.org/2010/04/fixing-health-care-on-the-front-lines/ar/1 Happiness Adaptation to Income beyond "Basic Needs" Authors:Rafael Di Tella and Robert MacCulloch Publication:Chap. 8 in International Differences in Well-Being, View Details

Keywords: Sean Silverthorne

01 Feb 2011
First Look

First Look: Feb. 1

including suggestions for future research. The Many Faces of Nonprofit Accountability Authors:Alnoor Ebrahim Publication:Chap. 4 in The Jossey-Bass Handbook of Nonprofit Leadership and Management. 3rd ed., edited by David O. Renz,... View Details

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